Results 81 to 90 of about 34,622 (239)
Chemistry &Biodiversity, Volume 22, Issue 12, December 2025.Compound A3bn exhibited strong binding affinities for HDAC2, HDAC6, and HDAC8. A3bn’s anticancer IC50 values were similar to those of SAHA. Cell death resulted from the extrinsic apoptotic pathway. Compound A3bn, a hydrophilic linker, which promotes zinc coordination, may be the cause of its increased activity across HDAC isoforms. ABSTRACT Unregulated
Nedaa A. Abd Al Rahim +8 more
wiley +1 more source
Recovery of Liquid Organic Radioactive Waste Absorbed Into Soil by Extraction
CleanMat, Volume 2, Issue 4, Page 285-296, December 2025.Radioactive organic liquid waste adsorbed in soil containing pure beta‐emitting radionuclides such as H‐3 must be radiologically characterized for subsequent management. For this purpose, a method for the recovery of radioactive scintillation liquids adsorbed in soil has been developed that simulates this type of waste.
Fabiola Monroy‐Guzman +5 more
wiley +1 more source
2-Phenyl-5-(p-tolyl)-1,3,4-oxadiazole [PDF]
Acta Crystallographica Section E Structure Reports Online, 2011 The title compound, C(15)H(12)N(2)O, adopts the expected near-planar geometry, the phenyl and tolyl rings being inclined relative to the oxadiazole ring by 3.8 (3) and 8.3 (2)°, respectively. This allows adjacent mol-ecules to pack in a parallel fashion and form stacking along [010] via π-π inter-actions [centroid-centroid distances = 3.629 (2) and 3 ...
Cordes, David B. +3 more
openaire +5 more sources
FlexMat, Volume 2, Issue 4, Page 533-581, December 2025.The enhanced utilization of triplet excitons is a central theme in the evolution of organic luminescent materials. This review sums up recent research on multi‐channel charge transfer delayed fluorescence molecules, which exhibit a unique distribution of excited‐state energy levels, thereby enhancing the utilization rate of triplet excitons and ...
Guo‐Wei Chen +6 more
wiley +1 more source
Design, Synthesis and Evaluation of New Bioactive Oxadiazole Derivatives as Anticancer Agents Targeting Bcl-2 [PDF]
, 2020 A series of 2-(1H-indol-3-yl)-5-substituted-1,3,4-oxadiazoles, 4a–m, were designed, synthesized and tested in vitro as potential pro-apoptotic Bcl-2 inhibitory anticancer agents based on our previously reported hit compounds.
El-Sadek, Mohamed +6 more
core +4 more sources
Advanced Science, Volume 12, Issue 42, November 13, 2025.CRB‐2131, as a novel Nox inhibitor, suppresses brain oxidation, tauopathy, and neuro‐inflammation, thereby preventing death of mature neurons and promoting regeneration of immature neurons. Ultimately, this fosters a resilient brain and protects cognition.
Jihyeon Lee +13 more
wiley +1 more source
Molecular Docking Studies of 2-Mercapto-5-(3-Methoxyphenyl) 1, 3, 4 Oxadiazole Thiones with Focal Adhesion Kinase [PDF]
, 2014 The main objective of the present work is to perform molecular docking studies of the ligand 2- Mercapto-5-(3-Methoxy phenyl) 1,3,4 oxadiazole with protein focal adhesion kinase. A good correlation was observed in binding affinity of this complex.
Guruprasad, R. +2 more
core
Identification of New CD36 Antagonists by Structure‐Based Virtual Screening
Chemical Biology &Drug Design, Volume 106, Issue 5, November 2025.Virtual screening identified drug‐like molecules as potential CD36 antagonists; some of them inhibited CD36 function in relevant cellular models. These antagonists could drive the development of CD36‐targeted therapies. ABSTRACT CD36 is a transmembrane glycoprotein that facilitates the uptake of fatty acids and oxidized low‐density lipoproteins.
Sandra L. Guerrero‐Rodríguez +8 more
wiley +1 more source
مجلة بغداد للعلوم, 2019 Allopurinol derivative were prepared by reacting the (1-chloroacetyl)-2-Hydropyrazolo{3,4-d}pyrimidine-4-oneiwith 5- methoxy- 2-aminoibenzothiazoleiunder certain conditions to obtain new compound ( N- (2-aminoacetyl (5-methoxy) benzothiazole -2yl) (A4),
Khammas et al.
doaj +1 more source
Electrochemical Dehydration Reaction
ChemSusChem, Volume 18, Issue 20, October 23, 2025.Electrochemical dehydration reactions are a fascinating and underexplored field of research in the domain of electrosynthesis. They offer a sustainable alternative to hazardous and harsh dehydration reagents. In this review, the recent progress that has been made in this emerging research topic is surveyed.
Johannes Schneider +2 more
wiley +1 more source