Results 41 to 50 of about 3,168 (197)

Синтез похідних 3-метил-6-R-[1,2,4]триазоло[3,4-b][1,3,4]тіадіазолу [PDF]

, 2020
Aim. To conduct the synthesis and confirm the structure of 3-methyl-6-R-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole derivatives as potential biologically active compounds.Results and discussion.
Hlazunova, Tetiana V., Knysh, Yevhen G., Panasenko, Olexandr I.   +2 more
core   +2 more sources

Synthesis and Evaluation of Antimicrobial Activity of 1, 3, 4-Thiadiazole Analogues for Potential Scaffold

Journal of Pharmacopuncture, 2021
Objectives: Pathogenic microbes are causal agents for various types of severe and even lethal infectious diseases. Despite of development in medication, bacterial and fungal infections still persist to be a vital problem in health care.
Sagar Sahu, Tanesh Sahu, Gunjan Kalyani, Bina Gidwani   +3 more
doaj   +1 more source

Synthesis, Spectral Studies and Antimicrobial Activity of imidazo[2,1-b][1,3,4]thiadiazole derivatives [PDF]

, 2017
Thiadiazole is a heterocyclic compound containg both two nitrogen atom and one sulfur atom as a part of the aromatic five-membered ring. The imidazo [2,1-b]-1,3,4-thiadiazole ring system is the core skeleton of well known immunomodulator levamisole.
Gupta, Monika, Gupta, Vivek Kumar, Kaur, Baljeet, Singh, Shailender Pratap   +3 more
core   +2 more sources

New Route Synthesis of Thiadiazoles, Bisthiadiazoles, Thiadiazolotriazines, and Pyrazolothiadiazoles Based on Hydrazonoyl Halides and Dihydrazinylthiadiazole

Molecules, 2017
Synthesis and characterization of new thiadiazoles, bisthiadiazoles from the reaction of mono- and di-hydrazonoyl halides with various hydrazinecarbodithioate derivatives were studied.
Abdelwahed R. Sayed, Shar Saad Al-Shihry
doaj   +1 more source

Synthesis and characterization of some novel 1,2,4-triazoles, 1,3,4-thiadiazoles and Schiff\u27s bases incorporating imidazole moiety as potential antimicrobial agents [PDF]

, 2015
(1,4,5-Triphenylimidazol-2-yl-thio)butyric acid hydrazide (3) was obtained via alkylation of 1,4,5-triphenylimidazol-2-thiol (1) with ethylbromobutyrate, followed by addition of hydrazine hydrate. Treatment of acid hydrazide 3 with carbon disulfide in an
ADEEB AL-SHEIKH ALI, ALAIN LESIMPLE, MOHAMED REDA AOUAD, MOUSLIM MESSALI, NADJET REZKI   +4 more
core   +3 more sources

Recent Developments In Chemistry Of 1,3,4-Thiadiazoles [PDF]

, 2014
The methods of preparation, structure and biological activities of 1,3,4-thiadiazoles are ...
Ismail, Mahmoud Fawzy, Mahmoud, Mahmoud Refaee   +1 more
core   +1 more source

Novel thiadiazole-thiazole hybrids: synthesis, molecular docking, and cytotoxicity evaluation against liver cancer cell lines

Journal of Taibah University for Science, 2022
One of the worst diseases, cancer claims millions of lives each year throughout the world, necessitating the creation of novel treatments. In this study, we designed a novel series of 1,3,4-thiadiazoles through the reaction of 2-(4-methyl-2-(2-(1 ...
Ghadah F. Aljohani, Tariq Z. Abolibda, Mohammad Alhilal, Jehan Y. Al-Humaidi, Suzan Alhilal, Hoda A. Ahmed, Sobhi M. Gomha   +6 more
doaj   +1 more source

Synthesis, Molecular Docking, and Preliminary Cytotoxicity Study of Some Novel 2-(Naphthalen-1-Yl)-Methylimidazo[2,1-B][1,3,4]Thiadiazoles [PDF]

, 2021
A series of 2-(naphthalen-1-yl)-methyl-6-arylimidazo[2,1-b][1,3,4]thiadiazole derivatives was prepared and studied for cytotoxicity against murine leukemia L1210, human cervix carcinoma HeLa, and human T-lymphocyte CEM cell lines.
..., B, Choodamani, B, Swapna, Karakurt, Tuncay, Karki, Subhas S., Setty, Ramachandra, Tahtaci, Hakan   +6 more
core   +1 more source

Synthesis and Antimicrobial Activity of New 5-(2-Thienyl)-1,2,4-triazoles and 5-(2-Thienyl)-1,3,4-oxadiazoles and Related Derivatives

Molecules, 2010
New 5-(2-thienyl)-1,2,4-triazoles and 5-(2-thienyl)-1,3,4-oxadiazoles namely, N-[3-mercapto-5-(2-thienyl)-1,2,4-triazol-4-yl]-N'-arylthioureas 4a–e, 2-arylamino-5-(2-thienyl)-1,2,4-triazolo[3,4-b][1,3,4]thiadiazoles 5a–e, 3-arylaminomethyl-5-(2-thienyl ...
Mohamed A. Al-Omar
doaj   +1 more source

SYNTHESIS AND ANTIMICROBIAL EVALUATION OF 2-[(SUBSTITUEDPHENYL)-5-(1-PHENYL-3-(PIPERAZINYL)PYRIDO[3,2-f]QUINAZOLIN-4(1H)-YL]-1,3,4-THIADIAZOLES [PDF]

, 2016
Several novel 2-[(substitutedphenyl)-5-(1-phenyl-3-(piperazinyl)pyrido[3,2-f] quinazolin-4(1H)-yl]-1,3,4 thiadiazole derivatives have been designed and synthesised by incorporating  four  known moieties  such  as  2-methylquinolin-5-ol, acetophenone ...
Chaudhary, Nidhi, Dubey, Ranjana, Ram, Tilak   +2 more
core   +2 more sources