Results 51 to 60 of about 1,311 (155)

A Convenient route for the synthesis of antimicrobial 1, 3, 4- thiadiazole derivatives

Bibechana, 2012
  Thiosemicarbazide of 6-chloro-2- aminobenzothiazole on cyclization with different aromatic carboxylic acids in Phosphorus oxychloride provided the corresponding 2-aryl-5-(6’-chloro-1’,3’-benzothiazole-2-yl-amino)-1,3,4-thiadiazoles 4a-j. The compounds
AD Mishra
doaj   +3 more sources

Newly synthesized Bis-Hydrazono[1,3,4] thiadiazoles as Anti-Alzheimer’s Agents: Greener past and In-Vitro acetylcholinesterase inhibition assay investigations

Journal of Saudi Chemical Society
The designed and synthesized multifunctional properties of bis-hydrazono[1,3,4]thiadiazoles became important for developing an efficient medication for Alzheimer’s disease.
Reem A.K. Alharbi, Sayed M. Riyadh, Nadia S. Al-Kaff, Musa A. Said   +3 more
doaj   +1 more source

Recent developments in the chemistry and enzyme inhibitory activity of fused thiazoles and thiadiazoles

Vietnam Journal of Chemistry, Volume 63, Issue 6, Page 872-882, December 2025.
Abstract The combination of cyclization reactions of thiadiazoles and benzothiazoles with Pd‐catalyzed cross‐coupling reactions provided a convenient synthesis of annulated, fluorinated and non‐fluorinated heterocycles, such as 1,3,4‐thiadiazolo[3,2‐a]pyrimidin‐5‐ones, benzothiazolo[3,2‐a]pyridimidin‐4‐ones, benzothiazolo[2,3‐b]quinazolin‐12‐ones and ...
Peter Langer
wiley   +1 more source

Synthesis, Anticancer Evaluation, and Molecular Docking of Novel Thiazolobenzimidazole–Thiazole Hybrids as Potent Colon Cancer Inhibitors

ChemistryOpen, Volume 14, Issue 11, November 2025.
Novel benzimidazothiazole–thiazole hybrids are synthesized and evaluated for anticancer activity against HCT‐116 colon cancer cells. Compound 16b shows superior cytotoxicity over doxorubicin. Molecular docking confirms strong binding to 6MTU protein, and ADMET profiling indicates favorable pharmacokinetics and low toxicity.
Bader Huwaimel, Amr S. Abouzied, Magdi E. A. Zaki, Abdulwahab Alamri, Basant Farag, Saad Alqarni, Sobhi M. Gomha   +6 more
wiley   +1 more source

NEW DERIVATIVES OF 2-R1-N-(5-R)-1,3,4-THIADIAZOL-2-YL-BENZOLSULFONAMIDES: SYNTHESIS, PHYSICOCHEMICAL PROPERTIES AND BIOLOGICAL ACTIVITY PREDICTION [PDF]

Annals of Mechnikov's Institute, 2015
Introduction: The analysis of modern literature, including overseas one, showed that a lot of the scientific researches is devoted to finding and creating biologically active compounds on base 1,3,4-thiadiazole.
Sych I.V., Perekhoda L.О., Іеremina Z.G.   +2 more
doaj  

Interfering Transposable Elements: ISXoo15 Transposase as a First‐in‐Class Antibacterial Target Against Xanthomonas oryzae pv. oryzae

Molecular Plant Pathology, Volume 26, Issue 11, November 2025.
The study identifies the previously unknown transposase ISXoo15 as an antiphytobacterial target. By constructing mutant strains, this enzyme's essential role in regulating bacterial pathogenicity and virulence is revealed. ABSTRACT Current challenges in controlling phytopathogenic bacteria lie in widespread chemical resistance, biosafety concerns, and ...
Funeng Lu, Ting Liu, Tangbing Yang, Ziming Wang, Jianzhuan Li, Chunni Zhao, Huan Wu, Deyu Hu, Baoan Song   +8 more
wiley   +1 more source

Ultrasound assisted synthesis of some new 1,3,4-thiadiazole and bi(1,3,4-thiadiazole) derivatives incorporating pyrazolone moiety

Ultrasonics Sonochemistry, 2009
Novel substituted 1,3,4-thiadiazole and bi(1,3,4-thiadiazole) were synthesized from reaction of 1-methyl-5-oxo-3-phenyl-2-pyrazolin-4-thiocarbox-anilide with a series of different hydrazonyl halides or N,N'-diphenyl-oxalodihydrazonoyl dichloride. The reactions were carried out under both conventional and ultrasonic irradiation conditions.
Naglaa M, Abd El-Rahman, Tamer S, Saleh, Mohamed F, Mady   +2 more
openaire   +2 more sources

Anti‐Corrosive Covalent Iodo‐Thiadiazole Catalyst Enables Aqueous Zn─S Batteries with High Coulombic Efficiency

Advanced Materials, Volume 37, Issue 43, October 29, 2025.
In aqueous Zn–S batteries, a covalently bonded iodo–thiadiazole redox mediator suppresses parasitic I3−‐mediated Zn corrosion and enhances Zn–S redox kinetics, enabling pouch cell with a high capacity of 1398 mAh g−1 after 120 cycles. This innovative catalyst design is a leap toward practical and grid‐scale aqueous Zn–S batteries. Abstract Aqueous zinc‐
Jiahao Liu, Yujie Chen, Han Wu, Chao Ye, Shi‐Zhang Qiao   +4 more
wiley   +1 more source

1,3,4-Thiadiazole-Containing Azo Dyes: Synthesis, Spectroscopic Properties and Molecular Structure

Molecules, 2020
Three series of azo dyes derived from 2-amino-5-aryl-1,3,4-thiadiazoles and aniline, N,N-dimethylaniline and phenol were synthesized in high yields by a conventional diazotization-coupling sequence.
Agnieszka Kudelko, Monika Olesiejuk, Marcin Luczynski, Marcin Swiatkowski, Tomasz Sieranski, Rafal Kruszynski   +5 more
doaj   +1 more source

Synthesis of Mesoionic 1,3,4-thiadiazoles

, 1968
Synthesis of Mesoionic 1,3,4 ...
P. B. Talukdar, S. K. Sengupta
openaire   +1 more source