Results 51 to 60 of about 42,977 (261)

A Suitable Functionalization of Nitroindazoles with Triazolyl and Pyrazolyl Moieties via Cycloaddition Reactions

open access: yesMolecules, 2019
The alkylation of a series of nitroindazole derivatives with 1,2-dibromoethane afforded the corresponding N-(2-bromoethyl)- and N-vinyl-nitro-1H-indazoles.
Mohammed Eddahmi   +9 more
doaj   +1 more source

Synthesis of Spirobidihydropyrazole through Double 1,3-Dipolar Cycloaddition of Nitrilimines with Allenoates.

open access: yesOrganic Letters, 2017
The double 1,3-dipolar cycloaddition of allenoates with nitrilimines has been achieved under mild reaction conditions, affording a variety of spirobidihydropyrazoles in moderate to excellent yields with excellent diastereoselectivities.
Honglei Liu   +4 more
semanticscholar   +1 more source

Synthesis and Application of Bioactive N‐Functionalized Aziridines

open access: yesAngewandte Chemie, EarlyView.
This review discusses modern synthetic methods for the preparation of aziridine‐containing small molecules, including biocatalytic, electrocatalytic, and photocatalytic strategies. We highlight the compatibility of various synthetic methods with control of the exocyclic N‐substituent.
Hao Tan   +4 more
wiley   +2 more sources

1,3-Dipolar Cycloadditions to Bicyclic Olefins. I. 1,3-Dipolar Cycloadditions to Norbornadienes [PDF]

open access: yesBulletin of the Chemical Society of Japan, 1977
Abstract The 1,3-dipolar cycloadditions of phenylglyoxylonitrile oxide, benzonitrile-N-phenylimine, or N-phenyl-C-p-nitrophenylnitrone to norbornadiene, 2,3-dicyanonorbornadiene, and 2,3-bis(methoxycarbonyl)norbornadiene give the endo-adducts, together with the exo-adducts.
Eiji Imoto   +3 more
openaire   +3 more sources

1,3 dipolar cycloaddition of münchnones: Factors behind the regio-selectivity

open access: yesThe Journal of Physical Chemistry A, 2022
The 1,3 dipolar cycloaddition reactions of münchnones and alkenes provide an expedite synthetic way to substituted pyrroles, an exceedingly important structural motif in the pharmaceutical and material science fields of research. The factors governing their regio-selectivity rationalization are not well understood.
Meylin Bocalandro   +3 more
openaire   +2 more sources

Synthesis of bis-spirocyclic derivatives of 3-azabicyclo[3.1.0]hexane via cyclopropene cycloadditions to the stable azomethine ylide derived from Ruhemann's purple

open access: yesBeilstein Journal of Organic Chemistry, 2022
A reliable method for the synthesis of bis-spirocyclic derivatives of 3-azabicyclo[3.1.0]hexanes through the 1,3-dipolar cycloaddition (1,3-DC) reactions of cyclopropenes to the stable azomethine ylide – protonated form of Ruhemann's purple (PRP) has ...
Alexander S. Filatov   +4 more
doaj   +1 more source

Enzymatic control of cycloadduct conformation ensures reversible 1,3 dipolar cycloaddition in a prFMN dependent decarboxylase

open access: yesNature Chemistry, 2019
The UbiD enzyme plays an important role in bacterial ubiquinone (coenzyme Q) biosynthesis. It belongs to a family of reversible decarboxylases that interconvert propenoic or aromatic acids with the corresponding alkenes or aromatic compounds using a ...
S. Bailey   +8 more
semanticscholar   +1 more source

Synthesis of Heterocylic Compounds of Biological Interest from Carbohydrate Derivatives

open access: yesMolecules, 2000
The synthesis of some isoxazolic compounds from carbohydrate derivatives is described. These products are obtained by 1,3-dipolar cycloaddition reaction and their functionalization leads to derivatives with potential biological activities.
M. F. Martinez Esperón   +2 more
doaj   +1 more source

PHOSPHONATED ISOXAZOLIDINYL NUCLEOSIDES, A NEW CLASS OF MODIFIED NUCLEOSIDES [PDF]

open access: yesEuromediterranean Biomedical Journal, 2014
This review offers an overview of the synthesis of phosphonated isoxazolidinyl nucleosides, a new class of interesting and potentially antiviral/antitumor agents.
Salvatore Giofrè
doaj   +1 more source

Büchwald-Hartwig reaction applied to synthesis of new luminescent liquid crystal triarylamines derived from isoxazoles [PDF]

open access: yes, 2015
© 2015 Taylor & Francis Group, LLC. The present work describes the synthesis and characterization of novel series of triarylamines isoxazoles (TAA) addressed to the organic photovoltaic materials. Diarylisoxazoles were synthesized by sequential [3+2] 1,
Fernandes, T. H. M.   +3 more
core   +2 more sources

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