Results 11 to 20 of about 2,516,936 (145)
18β-glycyrrhetinic acid inhibits lung adenocarcinoma progression by targeting the MET/AKT signaling axis [PDF]
Frontiers in Cell and Developmental BiologyBackground18β-Glycyrrhetinic acid (18β-GA), a major bioactive triterpenoid from licorice, has demonstrated anti-cancer potential; however, its mechanisms against lung adenocarcinoma (LUAD) remain unclear.MethodsThis study employed an integrated approach ...
Gongyu Wu +6 more
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Molecules, 2021 Chitosan is the only cationic polysaccharide found in nature. It has broad application prospects in biomaterials, but its application is limited due to its poor solubility in water.
Wei-Yan Quan +6 more
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Journal of Integrative Agriculture, 2023 Natural products have long been a crucial source of, or provided inspiration for new agrochemical discovery. Naturally occurring 18β-glycyrrhetinic acid shows broad-spectrum bioactivities and is a potential skeleton for novel drug discovery.
Ying-lian SONG +9 more
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Brazilian Journal of Pharmaceutical Sciences, 2023 The aim of the present study is to investigate the cardioprotective effects of 18β-glycyrrhetinic acid (18β -GA) against oxidative and histological damage caused by global cerebral ischemia/ reperfusion (I/R) in C57BL/J6 mice.
Neşe Başak Türkmen +6 more
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PLoS ONE, 2014 18β-Glycyrrhetinic acid (18β-GA) is a bioactive component of licorice. The anti-cancer activity of 18β-GA has been studied in many cancer types, whereas its effects in lung cancer remain largely unknown. We first showed that 18β-GA effectively suppressed
Run-Yue Huang +6 more
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Anti-Photoaging Effects of Nanocomposites of Amphiphilic Chitosan/18β-Glycyrrhetinic Acid [PDF]
Molecules, 2023 Improving the transdermal absorption of weakly soluble drugs for topical use can help to prevent and treat skin photoaging. Nanocrystals of 18β-glycyrrhetinic acid (i.e., NGAs) prepared by high-pressure homogenization and amphiphilic chitosan (ACS) were ...
Weiyan Quan +8 more
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Study on the mechanism of 18β-glycyrrhetinic acid inhibiting the proliferation of renal cancer cells by inducing autophagy through the miR-27a-5p/LC3 axis [PDF]
Frontiers in OncologyBackgroundRenal carcinoma is a common, aggressive urinary tract malignancy with notable clinical challenges such as severe treatment toxicity and poor patient outcomes; 18β-glycyrrhetinic acid (18β-GA), an active component of Chinese herb Glycyrrhiza ...
Shumin Jia +9 more
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Antibacterial activity of 18β-glycyrrhetinic acid against Neisseria gonorrhoeae in vitro [PDF]
Biochemistry and Biophysics Reports, 2023 Gonorrhea is the second most common sexually transmitted diseases worldwide. Chronic infection of Neisseria gonorrhoeae (N. gonorrhoeae) can lead to severe complications. Presently, N.
Yuanyuan Zhao, Xiaohong Su
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Pharmaceutical Biology, 2021 Context 18β-Glycyrrhetinic acid (18β-GA), a pentacyclic triterpenoid saponin metabolite of glycyrrhizin, exhibits several biological activities. Objective We investigated the effects of 18β-GA on MA104 cells infected with rotavirus (RV) and its potential
Xiaoyan Wang +5 more
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The Scientific World Journal, 2013 The triblock 18β-glycyrrhetinic acid-poly(ethylene glycol)-18β-glycyrrhetinic acid conjugates (GA-PEG-GA) based self-assembled micelles were synthesized and characterized by FTIR, NMR, transmission electron microscopy, and particle size analysis.
Fengbo Wu +6 more
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