Results 31 to 40 of about 1,247 (117)

Database-aided UHPLC-Q-orbitrap MS/MS strategy putatively identifies 52 compounds from Wushicha Granule to propose anti-counterfeiting quality-markers for pharmacopoeia

Chinese Medicine, 2023
Wushicha Granule, an over-the-counter-drug (OTC) prescription, consists of 19 traditional Chinese herbals medicines (CHMs), such as Chaihu, Hongcha, Chuanxiong, Houpo, and Gancao.
Xican Li, Shaoman Chen, Jingyuan Zeng, Rongxin Cai, Yilan Liang, Chuanbin Chen, Ban Chen, Chunhou Li   +7 more
doaj   +1 more source

Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy

Phytotherapy Research, Volume 40, Issue 8, Page 4759-4791, August 2026.
Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee, Yu Jin So, Il‐Joo Jo, Ji Yong Jang, Tae Han Yook, Jun Ho Lee, Sung Wook Kim, Kangwook Lee, Soo Jung Park, Gabsik Yang   +9 more
wiley   +1 more source

In silico and in vivo anti-malarial studies of 18β glycyrrhetinic acid from Glycyrrhiza glabra. [PDF]

PLoS ONE, 2013
Malaria is one of the most prevailing fatal diseases causing between 1.2 and 2.7 million deaths all over the world each year. Further, development of resistance against the frontline anti-malarial drugs has created an alarming situation, which requires ...
Komal Kalani, Jyoti Agarwal, Sarfaraz Alam, Feroz Khan, Anirban Pal, Santosh Kumar Srivastava   +5 more
doaj   +1 more source

Encounters With Traditional Medicine and Further Multidisciplinary and International Cooperation

Traditional &Kampo Medicine, Volume 13, Issue 2, August 2026.
ABSTRACT Background The integration of traditional medicine (TM) into modern healthcare has gained global momentum. Following the inclusion of TM in the 11th revision of the International Classification of Diseases, multidisciplinary and international cooperation has become increasingly essential.
Kokoro Ichihara, Ryota Sakoda, Yuto Matsuura, Hong‐Wook Choi, Toshiaki Makino, Tomoko Suzuki, Shin Takayama   +6 more
wiley   +1 more source

A Computational Strategy for Identifying Self‐Assembling Food‐Derived Molecules for Antiparasitic Nanotherapy

Advanced Science, Volume 13, Issue 39, 13 July 2026.
An integrated computational screening strategy identified ursolic acid (UA) and 18β‐glycyrrhetinic acid (18βGA) as a self‐assembling food‐derived molecular pair. The resulting carrier‐free nanoparticles (UA‐18βGA) showed synergistic antiparasitic activity, reduced combined toxicity, and host‐protective anti‐inflammatory effects in zebrafish and murine ...
Shenye Qu, Ting Wang, Jietao Liu, Jiacheng Qin, Bin Yang, Yihang Liu, Pengfei Li, Gaoxue Wang, Fei Ling   +8 more
wiley   +1 more source

Autophagy Inhibition by Fangji Huangqi Decoction Enhances Tumor Immunogenicity and Potentiates PD‐1 Blockade

Cancer Science, Volume 117, Issue 7, Page 1778-1794, July 2026.
In tumor cells, MHC‐I is typically degraded through autophagy, leading to reduced antigen presentation. However, Fangji Huangqi Decoction (FJHQ), acting as an autophagy inhibitor, suppresses lysosomal acidification, which in turn inhibits the degradation of MHC‐I. This results in increased surface expression of MHC‐I on tumor cells.
Yuxiao Jiang, Shiji Zeng, Dingye Wang, Junbo Jiang, Zhenzhen Li, Jingbi Li, Dan Chen, Xu Zhao, Zheng Ying, Yuehua Deng, Qianwei Cai, Silin Mai, Jiayi Zheng, Qiaohong Yang, Fang Liu, Biaoyan Du, Jianyong Xiao, Xiaoyi Liu, Kun Wang   +18 more
wiley   +1 more source

Glycyrrhetinic acid and its derivatives in infectious diseases

Current Issues in Pharmacy and Medical Sciences, 2016
Introduction. Licorice or liquorice (Glycyrrhiza glabra, Leguminosae) is a perennial plant naturally occurring or cultivated in Europe and Asia. It was appreciated by many ancient cultures, and was employed within Arabic medicine and (beginning in the ...
Langer Dominik, Czarczynska-Goslinska Beata, Goslinski Tomasz   +2 more
doaj   +1 more source

Traditional Respiratory Remedies From Anatolia: Ethnobotanical Insights and Bioactive Properties

Chemistry &Biodiversity, Volume 23, Issue 6, June 2026.
ABSTRACT Respiratory disorders, ranging from acute viral infections such as influenza and bronchitis to chronic inflammatory conditions including chronic obstructive pulmonary disease, asthma, emphysema, and pneumonia, represent a major global health burden, affecting millions annually. Traditional Anatolian folk medicine has long relied on plant‐based
Golshan Zare, Yağmur Diker, Irem Tatlı Çankaya, Emran Habibi, Satyajit D. Sarker, Lutfun Nahar   +5 more
wiley   +1 more source

18β-glycyrrhetinic acid accelerates liver regeneration after partial hepatectomy in mice

Medicine in Drug Discovery
Objective: 18β-Glycyrrhetinic acid (18β-GA), a key bioactive triterpenoid in Glycyrrhiza uralensis Fisch, is recognized for its hepatoprotective effects in liver injury.
Yuan Li, Yanxin Zhang, Guanqun Wan, Shaofei Song, Tingting Zhao, Renjie Cao, Weiwei Zeng, Min Huang, Yiming Jiang   +8 more
doaj   +1 more source

18β-Glycyrrhetinic Acid Inhibits Osteoclastogenesis In Vivo and In Vitro by Blocking RANKL-Mediated RANK–TRAF6 Interactions and NF-κB and MAPK Signaling Pathways

Frontiers in Pharmacology, 2018
Bone metabolism is determined by a delicate balance between bone resorption by osteoclasts and bone formation by osteoblasts. The imbalance due to over-activated osteoclasts plays an important role in various diseases.
Xiao Chen, Xiao Chen, Xin Zhi, Xin Zhi, Zhifeng Yin, Xiaoqun Li, Longjuan Qin, Zili Qiu, Jiacan Su, Jiacan Su   +9 more
doaj   +1 more source