Results 71 to 80 of about 4,897,037 (304)

In Situ Genetic Engineering Facilitates MMP‐9‐Responsive TIMP1 Release Through Proteolytic Cleavage to Boost Diabetic Wound Healing

open access: yesAdvanced Science, EarlyView.
This study develops an MMP‐9‐responsive protein release system that transforms resident cells into drug depots through in situ genetic engineering. Anchored to the membrane, the therapeutic protein TIMP1 is selectively released upon MMP‐9 cleavage.
Yuan Zhang   +11 more
wiley   +1 more source

Titanium implants modified by laser microtexturing enhance the bioactivity of gastric epithelial cells and fibroblast cells

open access: yesJournal of Applied Biomaterials & Functional Materials, 2021
The clinical application of anastomotic instruments improves the efficiency of the digestive tract surgery. However, the stapler with titanium nails implanted is still controversial in terms of anastomotic complications, and further improvement and ...
Zhaoxiong Zhang   +8 more
doaj   +1 more source

The 3T3-L1 cell under optical microscope.

open access: yes, 2022
The figure of 3T3-L1 cells in pre-staining. (A) Normal group. (B) 3T3-L1 cells were treated with differentiation medium. (C) 3T3-L1 cells were treated with cistanche of Boiled. (D) 3T3-L1 cells were treated with cistanche of Enzymed.
Le Su (276777)   +9 more
core   +1 more source

Heat‐Suppressing Projection Two‐Photon Lithography Enables High‐Throughput Sub‐Micrometer Manufacturing of Biopolymer Hydrogels for Tissue Engineering

open access: yesAdvanced Science, EarlyView.
The iLEAP technique integrates high‐throughput two‐photon lithography with extrusion printing, bridging sub‐micrometer precision and macroscopic scaffold fabrication. By employing a low‐exothermic photoinitiator, it mitigates thermal damage to biopolymers and preserves bioactivity.
Qifeng Guan   +11 more
wiley   +1 more source

Antidiabetic effect of combination of fractionated-extracts of Andrographis paniculata and Centella asiatica: In vitro study

open access: yesAsian Pacific Journal of Tropical Biomedicine, 2018
Objective: To examine the effect of combination of Andrographis paniculata herb fraction (AHF) and Centella asiatica herb fraction (CHF) on PPARγ and GLUT4 mRNA expressions in 3T3-L1 adipocyte, and its effect on insulin-stimulated glucose uptake. Methods:
LOM. Fitrawan   +4 more
doaj   +1 more source

Insulin-stimulated lipid accumulation is inhibited by ROS-scavenging chemicals, but not by the Drp1 inhibitor Mdivi-1. [PDF]

open access: yesPLoS ONE, 2017
Adipocyte differentiation is regulated by intracellular reactive oxygen species (ROS) generation and mitochondrial fission and fusion processes. However, the correlation between intracellular ROS generation and mitochondrial remodeling during adipocyte ...
Jung-Hak Kim   +5 more
doaj   +1 more source

Isorhamnetin Represses Adipogenesis in 3T3‐L1 Cells [PDF]

open access: yesObesity, 2009
Adipocyte dysfunction is strongly associated with the development of obesity, which is a major risk factor for many disorders including diabetes, hypertension, and heart disease. It is generally accepted that the regulation of adipogenesis or adipokines expression prevents obesity.
Jongsung, Lee   +9 more
openaire   +2 more sources

Localization of GFP-TBP in 3T3 cells and NT oocytes.

open access: yes, 2013
GFP-TBP localized at the nucleus of interphase 3T3 cells and chromosomes of M phase 3T3 cells. However, no GFP-TBP signal was found at the chromosomes of NT oocytes.
Shao-Chen Sun (257797)   +5 more
core   +1 more source

Stimulation of glucose utilization in 3T3 adipocytes and rat diaphragm in vitro by the sulphonylureas, glimepiride and glibenclamide, is correlated with modulations of the cAMP regulatory cascade [PDF]

open access: yes, 1994
The long-term hypoglycemic activity of sulphonylurea drugs has been attributed, in part at least, to the stimulation of glucose utilization in extra-pancreatic tissues. The novel sulphonylurea, glimepiride, gives rise to a longer lasting reduction in the
Wetekam, Eva-Marlen   +5 more
core   +1 more source

Rapid Photogelation of Low‐Concentration Polymer Solutions via Photodimerization of o‐Ethylnitrobenzene

open access: yesAdvanced Science, EarlyView.
Upon UV irradiation, flexible and tough hydrogels are formed rapidly (>0.5 s) from dilute (>0.5 wt%) solutions of o‐ethylnitrobenzene–modified PVA. At ∼1.5 wt%, the hydrogels withstand up to 10 MPa compression, remain handleable even after 200‐fold swelling.
Masaaki Okihara   +4 more
wiley   +1 more source

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