Results 81 to 90 of about 4,897,037 (304)

PPARγ expression is down-regulated in 3T3-A212P cells.

, 2013
(A) Western blot using an anti-PPARγ antibody showing PPARγ protein level in 3T3-CON, 3T3-WT and 3T3-A212P cells at the indicated time points during adipocyte differentiation. β-actin was used as a loading control. (B) Expression levels of PPARγ, C/EBPα,
Kenneth Wee (387154), Wenjie Qiu (387153), Xuemei Lim (387156), George K. Radda (198986), Weiping Han (198991), Kosuke Takeda (387155), Shigeki Sugii (387157)   +6 more
core   +1 more source

Defect‐Engineered BiO2‐X Nanosheets Mediate Sono‐Thermomechanical ECM Remodeling for Hepatocellular Carcinoma Immunotherapy

Advanced Science, EarlyView.
Herein, an ultrasound‐responsive BiO2‐X/siFn1 nanoplatform is developed to overcome anti‐PD‐1 resistance in hepatocellular carcinoma. Upon ultrasound irradiation, the platform downregulates fibronectin expression, while its sonothermal effect softens the dense extracellular matrix and activates antitumor immunity in the tumor microenvironment, thereby ...
Huimin Tian, Shen Zhang, Bolin Wu, Yichi Chen, Haitao Shang, Haoyan Tan, Chunyue Wang, Weichen Xu, Huixiong Xu, Haohao Yin, Wen Cheng   +10 more
wiley   +1 more source

Effect of differentiation on the adenylate cyclase system of 3T3-C2 and 3T3-L1 cells. Determination of choleragen substrates in differentiating 3T3-L1 and nondifferentiating 3T3-C2 cells.

Journal of Biological Chemistry, 1982
3T3-L1 preadipocytes, when treated with 3-isobutyl-1-methylxanthine, dexamethasone, and insulin, differentiate into cells with the morphological and biochemical properties of adipocytes; the closely related 3T3-C2 cells, under identical conditions, exhibit a low frequency of adipocyte conversion.
P A, Watkins, J, Moss, P H, Pekala, M D, Lane   +3 more
openaire   +2 more sources

Characteristics of 3T3-L1 cells with Brd2 knockdown.

, 2013
3T3-L1 cells were transfected with Brd2 shRNA (SiBrd2) or scramble shRNA (SiC) plasmids respectively. (A) Adipogenic differentiation of 3T3-L1 adipocytes from pre-adipocytes and Oil Red O staining on day 4 of treatment reveals lipids in cells that have ...
Jingyu Wang (292122), Min Yu (120607), Miaofang Dong (475610), Fangnian Wang (475613), Xiaoxia Liu (294088), Kun Zang (475609), Yuxiong Wang (152709), Yimin Li (475612), Ruixin Sun (475611), Yinong Huang (312166)   +9 more
core   +1 more source

Macrophage PARP7 Alleviates Septic Cardiomyopathy by Interacting With TBK1 and Suppressing TBK1‐Driven Inflammatory Response

Advanced Science, EarlyView.
In septic cardiomyopathy, PARP7 directly binds TBK1 and mediates its ADP‐ribosylation, thereby repressing TBK1‐driven proinflammatory signaling in macrophages. ABSTRACT Septic cardiomyopathy is a life‐threatening complication of sepsis, and an uncontrolled inflammatory response represents a key pathogenic mechanism. PARP7 negatively regulates the IFN‐I
Jibo Han, Lintao Wang, Xin Zhong, Shenggang Zhao, Huihui Xie, Xue Han, Liming Lin, Yiting Lyu, Ke Xu, Jiajun Xu, Xiaowen Shi   +10 more
wiley   +1 more source

In vitro antitumour activity, safety testing and subcellular distribution of two poly[oxyethylene(aminophosphonate-co-H-phosphonate)]s in Ehrlich ascites carcinoma and BALB/c 3T3 cell culture systems

Biotechnology & Biotechnological Equipment, 2016
Two polyphosphoesters containing anthracene-derived aminophosphonate and hydrophilic H-phosphonate repeating units, poly[oxyethylene(aminophosphonate-co-H-phosphonate)]s (1 and 2), were tested for the in vitro antitumour activity on cell cultures derived
Ani Georgieva, Ivan Iliev, Margarita Topashka-Ancheva, Ivanka Kraicheva, Ivelina Tsacheva, Emil Tashev, Tania Tosheva, Anton Kril   +7 more
doaj   +1 more source

TRB3 suppresses adipocyte differentiation by negatively regulating PPARγ transcriptional activitys⃞

Journal of Lipid Research, 2008
In the course of an effort to identify the regulators for peroxisome proliferator-activated receptor γ (PPARγ)-dependent perilipin gene expression, we found that tribbles homolog 3 (TRB3), containing a single kinase domain without enzymatic activity ...
Yu Takahashi, Nobumichi Ohoka, Hidetoshi Hayashi, Ryuichiro Sato   +3 more
doaj   +1 more source

Growth inhibitory effect associated with a series of cyanoquinoline molecules in 3T3, 3T3-MDR1, MCF7, and MCF7MX cells.

, 2016
A. Ratios of GI50 values in 3T3-MDR1 over GI50 values in 3T3 cells with and without pre-treatment with zosuquidar (zos). B. Ratios of GI50 values in MCF7MX over GI50 values in MCF7 cells with and without pre-treatment with fumitremorgin C (FTC).
Federica Pisaneschi (2694046), Graham Smith (279803), Rozanna L. Slade (3072048), Alice Beckley (3072039), Quang-De Nguyen (2401156), Eric O. Aboagye (309960), Laurence Carroll (3072045), Maciej A. Kaliszczak (3072042)   +7 more
core   +1 more source

Freestanding Hierarchical‐Porous BCZT Thin Films Enable Efficient Ultrasonic Energy Harvesting in Soft Tissue

Advanced Science, EarlyView.
Freestanding hierarchical‐porous BCZT thin films integrate a compliant porous surface with a dense piezoceramic backbone to balance mechanical reliability, voltage sensitivity, and acoustic coupling. The films enable stable wearable pulse‐wave monitoring and enhanced tissue‐coupled ultrasonic energy harvesting, offering a promising route toward soft ...
Zifan Li, Shengwei Gao, Wang Hong, Yuxin Chen, Yiyang Gu, Xu Wang, Chen Tang, Ying Hong, Xuemu Li, Xiaodong Yan, Yi Zheng, Yiming Liu, Junchen Liao, Biao Wang, Shiyuan Liu   +14 more
wiley   +1 more source

Expression of VPAC/PAC receptors in 3T3-L1 cells during differentiation of 3T3-L1 cells.

, 2013
A. qPCR analysis of the mRNA expression of VPAC/PAC receptors in 3T3-L1 two days post-confluent cells (day 0) and during differentiation till day 9.
Elodie Courtequisse (455776), Jason Perret (322187), Françoise Gregoire (3238308), Nargis Bolaky (455777), Tatjana Arsenijevic (322183), Jeanne Chiadak (455775), Christine Delporte (322186)   +6 more
core   +1 more source