Results 91 to 100 of about 12,849,117 (223)
Research in Pharmaceutical Sciences, 2019 1, 3, 4- Oxadiazoles and quinazolinones are privileged structures with extensive biological activities. On account of reported anticancer activity of them, in this study, a multi-step reaction procedure has been developed for the synthesis of some ...
Farshid Hassanzadeh +4 more
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SYNTHESIS AND EVALUATION OF ANTITUBERCULAR ACTIVITY OF 1, 3, 4-OXADIAZOLE DERIVATIVES
Asian Journal of Pharmaceutical and Clinical ResearchObjective: The present study aimed to design, synthesize, and evaluate two novel series of 1,3,4-oxadiazole derivatives for their antitubercular activity against Mycobacterium tuberculosis H37Rv, supported by molecular docking and absorption, bio-distribution, metabolism, and excretion (ADME) predictions to identify potential lead molecules.
null NAMITHA KN, null VELMURUGAN V
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, 2008 The uses of 1,2,4-oxadiazoles include those as agonists at muscarinic receptors, 5-hydroxytryptamine (5-HT) receptor antagonists, benzodiazepine receptor agonists, potent antagonists of the (serotonin) 5-HT1B/D receptors, muscarinic receptor ...
K. Hemming, Hemming, Karl, Hemming, K.
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, 1988 Department of Chemistry, Saurashtra. University, Rajkot-360 005 Manuscript received 4 February 1988, accepted 21 March 1988 Some new 2,6-disubstituted-1,3,4-oxadiazoles have been prepared having 2-arylsulphonamido and 2-α-carbamylarylmethylamino ...
V. L. PACHHAMIA, A. R. PARIKH
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, 2023 1. NMR spectra of synthetized compounds (Figures S1 to S112)2. Numbered structures of N-acylhydrazones and 1,3,4-oxadiazoles (Figures S113 and S114)
Flavio Augusto Vicente Seixas (8885993) +8 more
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Synthesis and photochemistry of di-substituted-1,2,4-oxadiazoles
, 2000 Four di-substituted-1,2,4-oxadiazoles were synthesized. They were tested by NMR, UV spectroscopy, and GC trace. The oxadiazoles were irradiated with 254nm and 300nm light to test their photoreactivity and attempt to prove benzonitrile was a ...
Adams, Alisha Marie
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مجلة بغداد للعلوم, 2019 Allopurinol derivative were prepared by reacting the (1-chloroacetyl)-2-Hydropyrazolo{3,4-d}pyrimidine-4-oneiwith 5- methoxy- 2-aminoibenzothiazoleiunder certain conditions to obtain new compound ( N- (2-aminoacetyl (5-methoxy) benzothiazole -2yl) (A4),
Khammas et al.
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Preparation of 2,5-Diaryl-1,3,4-Oxadiazoles [PDF]
, 1983 This report regards the research conducted in the synthesis of 2,5-disubstituted-1,3,4-oxadiazoles as potential insecticides which are closely related to the known insecticide DOWCO 416R, 2,5-bis(2,4-dichlorophenyl)-1,3,4-oxadiazole.
Dobe, Joachim D.
core
Synthesis and molecular modeling studies of novel pyrrole analogs as antimycobacterial agents
Journal of Saudi Chemical Society, 2013 In the present investigation, a series of 4-(4-pyrrol-1-yl/2,5-dimethyl-4-pyrrol-1-yl) benzoic acid hydrazide analogs, some derived oxadiazoles and azines have been synthesized in good yields and structures of these compounds were established by IR, 1H ...
Shrinivas D. Joshi +4 more
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Molecules, 2010 New 5-(2-thienyl)-1,2,4-triazoles and 5-(2-thienyl)-1,3,4-oxadiazoles namely, N-[3-mercapto-5-(2-thienyl)-1,2,4-triazol-4-yl]-N'-arylthioureas 4a–e, 2-arylamino-5-(2-thienyl)-1,2,4-triazolo[3,4-b][1,3,4]thiadiazoles 5a–e, 3-arylaminomethyl-5-(2-thienyl ...
Mohamed A. Al-Omar
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