Results 91 to 100 of about 9,297,922 (227)

Heterocycles from saccharide hydrazones. Part I. Saccharide 1,3,4-oxadiazoles [PDF]

, 1972
Oxidation, with iodine-mercuric oxide, of acetylated saccharide aroylhydrazones and of aromatic aldehyde hydrazones yields 5-aryl-2-(polyacetoxyalkyl)-1,3,4-oxadiazoles and 2,5-diaryl-1,3,4-oxadiazoles, respectively.
H. El Khadem, El Khadem, H., Shaban, M., Nassr, M., M. Nassr, M. Shaban   +5 more
core   +1 more source

5-Furan-2yl[1,3,4]oxadiazole-2-thiol, 5-Furan-2yl-4H [1,2,4] triazole-3-thiol and Their Thiol-Thione Tautomerism

Molecules, 2005
5-Furan-2-yl[1,3,4]oxadiazole-2-thiol (Ia) and 5-furan-2-yl-4H-[1,2,4]-triazole-3-thiol (Ib) were synthesized from furan-2-carboxylic acid hydrazide. Mannich basesand methyl derivatives were then prepared.
A. Cansız, A. Çetin, M. Koparır   +2 more
doaj   +1 more source

SYNTHESIS AND EVALUATION OF ANTITUBERCULAR ACTIVITY OF 1, 3, 4-OXADIAZOLE DERIVATIVES

Asian Journal of Pharmaceutical and Clinical Research
Objective: The present study aimed to design, synthesize, and evaluate two novel series of 1,3,4-oxadiazole derivatives for their antitubercular activity against Mycobacterium tuberculosis H37Rv, supported by molecular docking and absorption, bio-distribution, metabolism, and excretion (ADME) predictions to identify potential lead molecules.
null NAMITHA KN, null VELMURUGAN V
openaire   +1 more source

Synthesis, toxicity towards brine shrimp (Artemia salina Leach) and antimicrobial activity evaluation of 3,5-diphenylchlorinated-1,2,4- oxadiazoles = Síntese, toxicidade frente a Artemia salina Leach e avaliação da atividade antimicrobiana de 1,2,4-oxadiazóis-3,5-difenilclorados

Acta Scientiarum: Technology, 2005
The known oxadiazoles 3,5-bis-(phenyl)-1,2,4-oxadiazole (3a); the 3-(4-chlorophenyl)-5-phenyl-1,2,4-oxadiazole (3b); and the new 3,5-diphenylchlorinated-1,2,4-oxadiazoles 3c-e were synthesized from the reaction of benzamidoximes with an appropriated acid
Silvio Luiz Machado, Luciane Vieira dos Santos, Willian Ferreira da Costa, Benedito Prado Dias Filho, Maria Helena Sarragiotto   +4 more
doaj  

SYNTHESIS AND BIOLOGICAL EVALUATION OF 1H-(INDOLE-5-YL)-3-SUBSTITUTED-1,2,4-OXADIAZOLES AS NOVEL 5-LOX INHIBITORS

Journal of the Turkish Chemical Society, Section A: Chemistry
: A series of indolyloxadiazoles were synthesized from amidoxime and indole 3-carboxaldehyde using CAN as a catalyst and PEG as a solvent. In vitro, a 5-LOX inhibitory assay has been performed for all the synthesized compounds. Among the tested compounds,
Siddaiah Vidavalur, Sunanda Kumari Kadiri, Berihu Tekluu   +2 more
doaj   +1 more source

Push–Pull Ynamines and Push–Pull Ynamides: Synthesis, Structure, Reactivity, and Application

European Journal of Organic Chemistry, Volume 29, Issue 19, 22 May 2026.
Push–pull ynamines and push–pull ynamides, which carry an EWG and an amino or amido group as EDG, are highly interesting classes of EDG‐EWG alkynes that have been intensively studied due to their exceptional reactivity. In this review, the synthesis, structure, reactivity, and application of push–pull ynamines, push–pull ynecarbamates, push–pull ...
Hans‐Joachim Gais
wiley   +1 more source

Synthesis and cytotoxic evaluation of some quinazolinone- 5-(4-chlorophenyl) 1, 3, 4-oxadiazole conjugates

Research in Pharmaceutical Sciences, 2019
1, 3, 4- Oxadiazoles and quinazolinones are privileged structures with extensive biological activities. On account of reported anticancer activity of them, in this study, a multi-step reaction procedure has been developed for the synthesis of some ...
Farshid Hassanzadeh, Hojjat Sadeghi-Aliabadi, Elham Jafari, Azadeh Sharifzadeh, Nasim Dana   +4 more
doaj   +1 more source

Mechanistic Paths for the Gold(I)‐Catalyzed Heteroannulation of Salicylic Amides With Apolar Alkynes Explored With Density Functional Theory Calculations

European Journal of Organic Chemistry, Volume 29, Issue 18, 14 May 2026.
A manifold of catalytic reaction paths can operate in the Au(I)‐catalyzed heteroannulation of salicylic amides and alkynes. However, a subtle initial nucleophilic advantage of N versus O and a kinetic bottleneck at an advanced stage of the mechanistic machinery seems to suffice for the reaction to run on a single path and with exquisite selectivity. We
Ioannis Stylianakis, Evaggelia Vlachou, Carlos Silva López, Antonios Kolocouris   +3 more
wiley   +1 more source

Synthesis of Amino-1,2,4-triazoles by Reductive ANRORC Rearrangements of 1,2,4-Oxadiazoles. [PDF]

, 2010
The reaction of various 1,2,4-oxadiazoles with an excess of hydrazine in DMF has been investigated. 3-Amino- 1,2,4-triazoles are produced through a reductive ANRORC pathway consisting of the addition of hydrazine to the 1,2,4-oxadiazole followed by ...
PALUMBO PICCIONELLO, Antonio, Antonio Palumbo Piccionello, GUARCELLO, Annalisa, Silvestre Buscemi, Nicolò Vivona, Andrea Pace, BUSCEMI, Silvestre, VIVONA, Nicolo', PACE, Andrea, Annalisa Guarcello   +9 more
core   +1 more source

Síntese de ligantes fotoluminescentes derivados do heterociclo 1,3,4-oxadiazol [PDF]

, 2005
TCC (graduação) - Universidade Federal de Santa Catarina. Centro de Ciências Físicas e Matemáticas. Curso de Química.A síntese, de novos compostos fotoluminescentes contendo o heterociclo 1,3,4-oxadiazol são descritas.
FRIZON, Tiago Elias Allievi
core