Synthesis and Characterization of Some New Morpholine Derivatives [PDF]
, 2016 In this paper a new series of morpholine derivatives was prepared by reacting the morpholine with ethyl chloro acetate in the presence triethylamine as a catalyst in benzene gave morpholin-N-ethyl acetate(1) which reacted with hydrazine hydrate in ...
AlKaissi, Sura S. +2 more
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Synthesis, Characterization & Biological Evaluation of Some Novel 1, 3, 4-Oxadiazole Derivatives [PDF]
, 2019 Substituted oxadiazole, 5-(2-hydroxyphenyl)-1, 3, 4-oxadiazole-2(3H)-thione was synthesized from salicylic acid. The titled oxadiazole derivatives were synthesized by making substitution at free N-(3H) position of 5-(2-hydroxyphenyl)-1, 3, 4 ...
Abirami, A V
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Antibacterial and Enzyme Inhibition Study of Hydrazone Derivatives Bearing 1, 3, 4-Oxadiazole
Pakistan Journal of Chemistry, 2015 The antibacterial and lipoxygenase enzyme inhibition activities of two series of compounds have been investigated in the presented work. The 4-methyl/hydroxy benzoic acids (1a & 1b) were used as starting materials to prepare corresponding esters (2a & 2b), hydrazides (3a & 3b), 5-(4-methylphenyl/4-hydroxyphenyl)-1,3,4-oxadiazol-2-thiols (4a & 4b), S ...
S. Rasool +7 more
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Synthesis, Characterization And Antimicrobial Activity Of Novel Substituted Aryl- 1,3,4-Oxadiazolo-[3,2-A]-1,3,5-Triazine Derivatives [PDF]
, 2014 Bioactive heterocyclic rings 1,3,4-oxadiazole and 1,3,5-triazine are fused with expectation of enhanced biological activity of the newly synthesized compounds. Hence Synthesized fused heterocyclic compounds as a substituted aryl- 1,3,4-oxadiazolo-[3,2-a]-
Basedia, Deepak Kumar +3 more
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Efficacy of 5-(2-aroyl)aryloxy methyl-2-phenyl-1,3,4-oxadiazoles as antibacterial and antifungal agents [PDF]
, 2013 Research and development of potent and effective antimicrobial agents represent one of the most important advances in therapeutics; the main aim of these efforts is not only control the serious infections, but also prevention and treatment of some ...
Asha, M. S. +5 more
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Design, synthesis, and apoptotic antiproliferative action of new benzimidazole/1,2,3-triazole hybrids as EGFR inhibitors [PDF]
Introduction This work outlines the design, synthesis, and biological evaluation of a new series of benzimidazole/1,2,3-triazole hybrids as apoptotic antiproliferative agents that inhibit the EGFR pathway.Methods The research assesses the ...
Ahmed, Alshimaa A. Y. +4 more
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Biological Evaluation of Novel Synthesized 2, 5-disubstituted-1, 3, 4-oxadiazole derivatives
Journal of Drug Delivery and Therapeutics, 2019 Synthesis of a series of various 2, 5-disubstituted-1, 3, 4-oxadiazole derivatives (7a-7v) have been done previously. These novel synthesized derivatives (7a-7v) have been tested for their antibacterial activity against Gram +ve S. aureus and Gram -ve E. Coli bacterias by broth dilution method.
Raghvendra Singh Bhadauria +2 more
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Graph theoretical analysis, pharmacoinformatics and molecular docking investigation of Chalcone-Schiff base hybrids as Cyclin-Dependent kinase inhibitors [PDF]
One of the promising classes of compounds in medicinal chemistry and drug design is those with azomethine linkages. The Chalcone-Schiff base hybrids contain this linkage and some heteroatoms, which are versatile molecules, play a vital role in drug ...
Arivanantham, Sathishkumar +5 more
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Synthesis and Characterization of Co (Ii) And Ni (Ii) Complexes of 2, 5- Substituted 1, 3, 4-Oxadiazole Derivatives [PDF]
, 2020 Eight new Co ...
Selvaraj A, Subha C
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EX VIVO ANTICOAGULANT ACTIVITY OF 1, 3, 4-OXADIAZOLE DERIVATIVES [PDF]
, 2015 Objective: The present medication for the management of arterial thromboembolism (ATE) disorders by anticoagulant therapy highlights its lacunae due to recurrent ATE episodes and indicates the need for better anticoagulant agents with clinical advantage ...
Gurupadayya, B. M., Vishwanathan, B.
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