Results 81 to 90 of about 12,849,117 (223)

Orientational properties of 1,3,4-oxadiazoles in liquid-crystalline materials determined by electronic absorption and fluorescence measurements

open access: yes, 2022
S.753-760The electronic absorption and fluorescence spectra of two 4-donor/4 '-acceptor substituted 2,5-diphenyl-1,3,4-oxadiazole derivatives in isotropic solvents (methanol, toluene), in a commercial mixture of low molecular mass liquid crystals - ZLI ...
Wolarz, E.   +3 more
core   +1 more source

Heterocyclic‐Based Fungicides: Emerging Strategies for Viable Plant Disease Control

open access: yesChemistry &Biodiversity, Volume 23, Issue 9, September 2026.
Heterocyclic compounds have attracted considerable attention because of their structural diversity, potent antifungal activity, and ability to interact with multiple fungal targets, offering broad‐spectrum protection against phytopathogens. Synthetic and semisynthetic/part‐natural scaffolds, particularly azole, quinoline, indole, cyclotryptamine, and ...
Sumit Tahlan   +4 more
wiley   +1 more source

Anion-Driven C–F Bond Activation of Trifluoromethyl N‑Aryl Hydrazones: Application to the Synthesis of 1,3,4-Oxadiazoles

open access: yes
The CF3 group attached to N-aryl hydrazone could be activated upon treatment with a suitable base, thus serving as an excellent C1 unit for the assembly of a series of 1,3,4-oxadiazoles by reaction with hydrazides.
Fangyi Li (1566442)   +5 more
core   +1 more source

Editorial for Special Issue “Bioactive Oxadiazoles”

open access: yes, 2021
Oxadiazoles are electron-poor, five-membered aromatic heterocycles containing one oxygen and two nitrogen atoms [...
Antonio Palumbo Piccionello
core   +1 more source

Synthesis, toxicity towards brine shrimp (Artemia salina Leach) and antimicrobial activity evaluation of 3,5-diphenylchlorinated-1,2,4- oxadiazoles = Síntese, toxicidade frente a Artemia salina Leach e avaliação da atividade antimicrobiana de 1,2,4-oxadiazóis-3,5-difenilclorados

open access: yesActa Scientiarum: Technology, 2005
The known oxadiazoles 3,5-bis-(phenyl)-1,2,4-oxadiazole (3a); the 3-(4-chlorophenyl)-5-phenyl-1,2,4-oxadiazole (3b); and the new 3,5-diphenylchlorinated-1,2,4-oxadiazoles 3c-e were synthesized from the reaction of benzamidoximes with an appropriated acid
Silvio Luiz Machado   +4 more
doaj  

SYNTHESIS AND BIOLOGICAL EVALUATION OF 1H-(INDOLE-5-YL)-3-SUBSTITUTED-1,2,4-OXADIAZOLES AS NOVEL 5-LOX INHIBITORS

open access: yesJournal of the Turkish Chemical Society, Section A: Chemistry
: A series of indolyloxadiazoles were synthesized from amidoxime and indole 3-carboxaldehyde using CAN as a catalyst and PEG as a solvent. In vitro, a 5-LOX inhibitory assay has been performed for all the synthesized compounds. Among the tested compounds,
Siddaiah Vidavalur   +2 more
doaj   +1 more source

Deciphering the Medicinal Chemistry Aspects of Akt Inhibitors for the Management of Cancer: Structure–Activity Relationship Frameworks, Landscapes, and Optimization Approaches

open access: yesChemistry &Biodiversity, Volume 23, Issue 9, September 2026.
This review majorly describes the systematic development of Akt inhibitors involving numerous heterocyclic scaffolds along with their structure activity relationships to explore anticancer therapeutic strategies. ABSTRACT The Akt pathway is dysregulated in cancer, leading to proliferation, decreased apoptosis, and metastasis, and hence is a major ...
Mayur S. Dhangar, Mahesh B. Palkar
wiley   +1 more source

Recent Advances in the Chemistry of 1,2,4-Oxadiazoles

open access: yes, 2015
1,2,4-Oxadiazoles experienced an almost 80-year long period of scientific lethargy before they tickled the curiosity of chemists. The study of chemical and photochemical reactivity of 1,2,4-oxadiazoles opened the way to a series of applications in ...
Ivana Pibiri   +7 more
core   +1 more source

Intramolecular Diels−Alder/1,3-Dipolar Cycloaddition Cascade of 1,3,4-Oxadiazoles

open access: yes, 2016
Full details of a systematic exploration of the intramolecular [4 + 2]/[3 + 2] cycloaddition cascade of 1,3,4-oxadiazoles are disclosed in which the scope and utility of the reaction are ...
James R. Fuchs (143921)   +6 more
core   +2 more sources

DESIGN, SYNTHESIS AND ANTIFUNGAL EVALUATION OF NOVEL SUBSTITUTED 1, 3, 4-OXADIAZOLES, AND 1, 3, 4-THIADIAZOLES [PDF]

open access: yes, 2015
Objective: The purpose of this research is to evaluate the antifungal activity of synthesized conjugates of thiophene with 1, 3, 4-oxadiazoles and 1, 3, 4-thiadiazoles using in vitro methods.Methods: The series of (IVa-e) and (Va-e) compounds were ...
Mishra, Pradeep, Upadhyay, Prabhat K
core   +1 more source

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