Results 81 to 90 of about 3,269 (232)
Molecules, 2005 5-Furan-2-yl[1,3,4]oxadiazole-2-thiol (Ia) and 5-furan-2-yl-4H-[1,2,4]-triazole-3-thiol (Ib) were synthesized from furan-2-carboxylic acid hydrazide. Mannich basesand methyl derivatives were then prepared.
A. Cansız +2 more
doaj +1 more source
The synthesis of potential analgesics derived from thebaine [PDF]
, 1979 The thesis describes the synthesis of novel bridged thebaine derivatives with heterocyclic rings attached to C-7 and a study of the associated chemistry. Use has been made of the α-hydrazide (3) formed from the α-ester (2), itself prepared by Diels-Alder
Michael Burton (4178776)
core
Drug Development Research, Volume 87, Issue 2, April 2026.ABSTRACT SIRT2, the cytoplasmic member of the sirtuin family, is generally acknowledged to promote cancer and contribute to the progression of various pathologies, including neurodegeneration, inflammation, obesity, and bacterial infection through the deacetylation of target substrates.
Ahmet Bugra Aksel +9 more
wiley +1 more source
Advanced supersonic technology fuel tank sealants [PDF]
Status of the fuel tank simulation and YF-12A flight tests utilizing a fluorosilicone sealant is described. New elastomer sealant development is detailed, and comparisons of high and low temperature characteristics are made to baseline fluorosilicone ...
Parker, J. A., Rosser, R. W.
core +1 more source
Synthesis and antiviral activity of 2-3,5 dinitropheny1-5-substituted phenyl 1,3,4-oxadiazoles [PDF]
, 2020 3, 5 dinitro benzoic acid hydrazide was prepared by the hydrazinolysis of the corresponding ethyl ester. Condensation of this hydrazide with different aromatic acids in presence of POCl3 gave 2-3, 5 dinitropheny1-5-substituted pheny1 1, 3, 4-oxadiazoles.
Jyoti, Archana
core
Drug Development Research, Volume 87, Issue 2, April 2026.ABSTRACT A new series of aliphatic‐substituted benzimidazole derivatives was synthesized and structurally characterized to evaluate their potential anticancer activity. Among the synthesized compounds, compound 4 exhibited the most potent cytotoxic effects against MCF‐7 and MDA‐MB‐231 breast cancer cell lines, with IC₅₀ values comparable to those of ...
Murat Keser +7 more
wiley +1 more source
Research in Pharmaceutical Sciences, 2019 1, 3, 4- Oxadiazoles and quinazolinones are privileged structures with extensive biological activities. On account of reported anticancer activity of them, in this study, a multi-step reaction procedure has been developed for the synthesis of some ...
Farshid Hassanzadeh +4 more
doaj +1 more source
EcoMat, Volume 8, Issue 4, April 2026.A sustainable rewritable paper platform is developed using biopolymer‐based aqueous colored inks and organic acid–treated substrates. Localized protonation induces in situ fibrous hydrogel network formation that anchors dyes for stable handwriting, painting, and inkjet printing.
Damini Jagankar +2 more
wiley +1 more source
Cross Linking and Degradation Mechanisms in Model Sealant Candidates [PDF]
Model compounds were investigated as to which type of heterocyclic ring is the most advantageous for curing sealants based on perfluoroalkylether chains. The relative thermal, thermal oxidative, hydrolytic, and fuel stability of potential crosslinks were
Ito, T. I. +4 more
core +1 more source
In Silico, In Vitro, and In Vivo Antinociceptive Potential of S‐Naproxen Derivatives
ChemistryOpen, Volume 15, Issue 4, April 2026.Selected naproxen derivatives were investigated for their antinociceptive effects, using in vitro (COX‐I/COX‐II antagonistic effect), in vivo (acetic acid and hot plate assay), and in silico (molecular simulation studies) approaches. The COX inhibition studies revealed that the maximum percent effect exhibited by GMO‐I‐111a 96.01 and 92% against COX‐2 ...
Ubaidullah +13 more
wiley +1 more source