Synthesis and molecular modeling studies of novel pyrrole analogs as antimycobacterial agents
In the present investigation, a series of 4-(4-pyrrol-1-yl/2,5-dimethyl-4-pyrrol-1-yl) benzoic acid hydrazide analogs, some derived oxadiazoles and azines have been synthesized in good yields and structures of these compounds were established by IR, 1H ...
Shrinivas D. Joshi +4 more
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New 5-(2-thienyl)-1,2,4-triazoles and 5-(2-thienyl)-1,3,4-oxadiazoles namely, N-[3-mercapto-5-(2-thienyl)-1,2,4-triazol-4-yl]-N'-arylthioureas 4a–e, 2-arylamino-5-(2-thienyl)-1,2,4-triazolo[3,4-b][1,3,4]thiadiazoles 5a–e, 3-arylaminomethyl-5-(2-thienyl ...
Mohamed A. Al-Omar
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Polymers Containing 1, 3, 4-Oxadiazole Rings for Advanced Materials
This paper presents the synthesis, properties and potential applications of new polymers containing 1, 3, 4-oxadiazole rings, tacking into account the requirements of the modern technologies. Two classes of polymers containing oxadiazole rings were approached: polyamides and polyimides.
Mariana-Dana Damaceanu +2 more
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1, 3, 4-Oxadiazole: A Versatile Compound With Potent Analgesic Activity
Oxadiazole is a heterocyclic ring with 5 members that has 1 oxygen atom, 2 nitrogen atoms, 2 double bonds, and 2 carbons. In furan, they are created by placing two methylene groups (=CH) for two nitrogen (-N=) atoms. The aromaticity was reduced by the substitution of these groups. There were four different isomer of oxadiazole that were identified: 1,3,
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Syntheses of Poly(1, 2, 4-oxadiazole)-Polyimides
Toshiyuki SHONO +3 more
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A straightforward protocol for the synthesis of a previously unknown [1,2,5]oxadiazolo[3,4-d][1,2,3]triazin-7(6H)-one heterocyclic system was developed. The described approach is based on tandem diazotization/azo coupling reactions of (1,2,5-oxadiazolyl ...
Yuri A. Sidunets +2 more
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A Review On: Antifungal And Antibacterial Activity Of 1, 3, 4-Oxadiazole Derivatives
1,3,4-Oxadiazoles are five-membered heterocyclic compounds containing two nitrogen atoms and one oxygen atom. These versatile molecules exhibit a range of biological effects, including antibacterial, antifungal, and antiviral properties. Recent research has demonstrated that many 1,3,4-oxadiazole derivatives surpass the activity of existing antibiotics
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Design, synthesis, and enzyme kinetic evaluation of oxadiazole derivatives as nucleoside triphosphate diphosphohydrolase (NTPDase) inhibitors: an integrated <i>in vitro</i> and <i>in silico</i> approach. [PDF]
Abbas SZ +6 more
europepmc +1 more source
Mechanism-based inhibition of zinc-dependent histone deacetylases. [PDF]
Christianson DW.
europepmc +1 more source
Activity Profiling of Nitro-Substituted Di(Hetero)Aryl 1,3,4- and 1,2,4-Oxadiazoles: Antimicrobial, Cholinesterase Inhibition and Antioxidant Potential. [PDF]
Šikorová E +9 more
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