Results 31 to 40 of about 18,771 (284)

Synthesis of some substituted 1,3,4-oxadiazoles, thiadiazoles and 1,2,4-triazoles [PDF]

open access: yesمجلة التربية والعلم, 2009
In this paper the synthesis of some substituted 1,3,4-oxadiazoles, 1,3,4-thiadiazoles and 1,2,4-triazoles is reported. Ethyl methacrylate was treated with hydrazine hydrate in ethanol to give the corresponding hydrazide (1).
Shereen R. Mohamed
doaj   +1 more source

Synthesis, characterization and self-assembly of novel fluorescent alkoxy-substituted 1, 4-diarylated 1, 2, 3-triazoles organogelators

open access: yesArabian Journal of Chemistry, 2022
Novel organogelators based on fluorescent alkoxy-substituted 1,4-diarylated 1, 2, 3-triazoles are reported. The findings monitored in the current study promoted the development of inventive compacted supramolecular architectures generated by self ...
Salhah D. Al-Qahtani   +6 more
doaj  

Imaging of the calcium activated potassium channel 3.1 (KCa3.1) in vivo using a senicapoc‐derived positron emission tomography tracer

open access: yesArchiv der Pharmazie, Volume 355, Issue 12, December 2022., 2022
The 18F‐labeled derivative [18F]3 of senicapoc was synthesized using the prosthetic group approach with 1‐azido‐2‐[18F]fluoroethane ([18F]6) in a “click” reaction. The biological activity of the new positron emission tomography tracer was evaluated in vitro and in vivo.
Christian P. Konken   +11 more
wiley   +1 more source

Synthesis of New Bis-1,2,4-Triazole Derivatives

open access: yesMolecules, 2006
A series of new 1,2/1,3-bis[o-(N-methylidenamino-3-aryl-5-phenyl-4H-1,2,4-triazole-4-yl)phenoxy]ethane/propane derivatives 4 were prepared in good yields bytreatment of 4-amino-3-aryl-5-phenyl-4H-1,2,4-triazoles 2 with certain bis-aldehydes 1.Compounds 4
Hakan Bektas, Olcay Bekircan
doaj   +1 more source

SAR exploration of the non‐imidazole histamine H3 receptor ligand ZEL‐H16 reveals potent inverse agonism

open access: yesArchiv der Pharmazie, Volume 356, Issue 1, January 2023., 2023
ZEL‐H16 (1) has been disclosed to be a high‐affinity non‐imidazole H3R (partial) agonist. However, it was found that 1 acts as an inverse agonist for Gαi in various assays. Concise structure–activity relationship studies, molecular pharmacology, and docking were used to shed more light on the properties of 1.
Gábor Wágner   +12 more
wiley   +1 more source

Analysis of natural and anthropogenic factors aff ecting the ability of Lepidium sativum L. to adapt to the toxicity of triazole xenobiotics [PDF]

open access: yesИзвестия Саратовского университета. Новая серия: Серия Химия. Биология. Экология
The eff ects of natural factors (temperatures +34°C and +20°C) and anthropogenic xenobiotics (1,2,4-TriH; 1-(CH3 SO2 )-1H-1,2,4-Tri; 4-(PhSO2 )-4H-1,2,4-Tri; 4-(TolSO2 )-4H-1,2,4-Tri) on watercress Lepidium sativum L. was studied.
Isaichkin, Vadim A.   +2 more
doaj   +1 more source

H2O2‐Generating Advanced Nanomaterials for Cancer Treatment

open access: yesAdvanced Functional Materials, EarlyView.
H2O2‐generating nanoplatforms can exploit tumor redox imbalance for O2 and toxic reactive oxygen species generation, leading to hypoxia reversal, and apoptosis of cancer cells, respectively. This review highlights the mechanisms of these nanoplatforms, including exogenous H₂O₂ delivery, endogenous amplification, and metal peroxides, which leads to ...
Kiyan Musaie   +8 more
wiley   +1 more source

Combate del rocío azucarado (Sphacelia sorghi McRae) del sorgo (Sorghum bicolor (L.) Moench) con funguicidas.

open access: yesAgronomía Mesoamericana, 2006
Con el objetivo de determinar la efectividad de cinco fungicidas en el combate del rocío azucarado del sorgo causado por Sphacelia sorghi McRae, se llevó a cabo un experimento en el campo experimental del Centro Nacional de Investigaciones Agropecuarias ...
Héctor Mena   +4 more
doaj   +1 more source

Synthesis and Spectral Study of a New Family of 2,5-Diaryltriazoles Having Restricted Rotation of the 5-Aryl Substituent

open access: yesMolecules, 2020
Efficient synthesis of 2,5-diaryl substituted 4-azido-1,2,3-triazoles by the reaction of sodium azide with dichlorosubstituted diazadienes was demonstrated.
Biligma Tsyrenova, Valentine Nenajdenko
doaj   +1 more source

Some transformations and physicochemical properties of new S-substituted 5-thiophene-(3-ylmethyl)-4R-1,2,4-triazole-3-thiols

open access: yesФармацевтичний журнал, 2021
Nitrogen-containing heterocyclic compounds are widely represented in modern organic chemistry. A special place among the huge number of substances presented is occupied by derivatives of 1,2,4-triazole due to their uniqueness and prospects.
A. V. Khilkovets
doaj   +1 more source

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