Results 61 to 70 of about 2,779,849 (194)

Genomic Positional Dissection of RNA Editomes in Tumor and Normal Samples

Frontiers in Genetics, 2019
RNA editing is phenomenon that occurs in both protein coding and non-coding RNAs. Increasing evidence have shown that adenosine-to-inosine RNA editing can potentially rendering substantial functional effects throughout the genome.
Michael Chigaev, Hui Yu, David C. Samuels, Quanhu Sheng, Olufunmilola Oyebamiji, Scott Ness, Wei Yue, Ying-yong Zhao, Yan Guo   +8 more
doaj   +1 more source

A nomogram based on A-to-I RNA editing predicting overall survival of patients with lung squamous carcinoma

BMC Cancer, 2022
Background Adenosine-to-inosine RNA editing (ATIRE) is characterized as non-mutational epigenetic reprogramming hallmark of cancer, while little is known about its predictive role in cancer survival.
Li Liu, Jun Liu, Xiaoliang Deng, Li Tu, Zhuxiang Zhao, Chenli Xie, Lei Yang   +6 more
doaj   +1 more source

Emerging roles of the RNA modifications N6-methyladenosine and adenosine-to-inosine in cardiovascular diseases

Molecular Therapy: Nucleic Acids, 2022
Cardiovascular diseases lead the mortality and morbidity disease metrics worldwide. A multitude of chemical base modifications in ribonucleic acids (RNAs) have been linked with key events of cardiovascular diseases and metabolic disorders.
Vilbert Sikorski, Antti Vento, Esko Kankuri   +2 more
doaj   +1 more source

Cinema programs as a source for research on historical film audiences. Berlin 1945–1949 [PDF]

, 2015
In my paper, I analyse programs from cinemas in all four sectors of occupied Berlin from 1945 to 1949. I focus primarily on ads. Looking at cinema programs allows me to conduct research on local audiences by taking into consideration the social ...
Saryusz-Wolska, Magdalena
core   +1 more source

The growth, development and infection process of the plant pathogen Fusarium

Plant Signaling & Behavior
The genus Fusarium includes some of the most detrimental pathogenic fungi to crops, significantly impacting cereal growth and food production. It causes devastating diseases such as banana wilt caused by Fusarium oxysporum and Fusarium head blight caused
Zhuo Li, Fengying He, Xiaotong Gai, Hongyao Zhu, Shidao He, Yuan Hu Xuan, Luchao Bai   +6 more
doaj   +1 more source

The Integrative Studies on the Functional A-to-I RNA Editing Events in Human Cancers

Genomics, Proteomics & Bioinformatics, 2023
Adenosine-to-inosine (A-to-I) RNA editing, constituting nearly 90% of all RNA editing events in humans, has been reported to contribute to the tumorigenesis in diverse cancers.
Sijia Wu, Zhiwei Fan, Pora Kim, Liyu Huang, Xiaobo Zhou   +4 more
doaj   +1 more source

Peptide exchange on MHC-I by TAPBPR is driven by a negative allostery release cycle. [PDF]

, 2018
Chaperones TAPBPR and tapasin associate with class I major histocompatibility complexes (MHC-I) to promote optimization (editing) of peptide cargo. Here, we use solution NMR to investigate the mechanism of peptide exchange.
A Bailey, A Blees, A Hateren van, A Hateren van, A Neerincx, A Neerincx, Andrew C. McShan, Avan Hateren, B Park, B Rodenko, C Hermann, C Hermann, C Thomas, C Thomas, CA Waudby, Clive R. Bagshaw, CM Ayres, CS Hee, David Flores-Solis, David H. Margulies, DM Korzhnev, E Kurimoto, EL Kovrigin, ET Abualrous, Evgenii L. Kovrigin, F Delaglio, F Sieker, GI Morozov, H Li, IR Kleckner, J Jiang, J Neefjes, JH Lee, Jiansheng Jiang, Jugmohit S. Toor, K Natarajan, Kannan Natarajan, KL Rock, LH Boyle, LO Pedersen, M Beerbaum, M Chen, M Wieczorek, Mareike Badstübner, MJ Barnden, MP Latham, NA Lakomek, Nikolaos G. Sgourakis, O Fisette, P Rossi, PA Wearsch, PA Wearsch, QR Chen, S Paul, S Yanaka, SO Ryan, V Montserrat, V Tugarinov, Vlad K. Kumirov, W Lee, W Pos, Y Shionoya, Z Hein   +62 more
core   +1 more source

Temporal landscape and translational regulation of A-to-I RNA editing in mouse retina development

BMC Biology
Background The significance of A-to-I RNA editing in nervous system development is widely recognized; however, its influence on retina development remains to be thoroughly understood.
Ludong Yang, Liang Yi, Jiaqi Yang, Rui Zhang, Zhi Xie, Hongwei Wang   +5 more
doaj   +1 more source

Ways of Forgetting and Remembering the Eloquence of the 19th Century: Editors of Romanian Political Speeches [PDF]

, 2016
The paper presents a critical evaluation of the existing anthologies of Romanian oratory and analyzes the pertinence of a new research line: how to trace back the foundations of Romanian versatile political memory, both from a lexical and from an ...
Patraș, Roxana
core  

The contribution of Alu exons to the human proteome. [PDF]

, 2016
BackgroundAlu elements are major contributors to lineage-specific new exons in primate and human genomes. Recent studies indicate that some Alu exons have high transcript inclusion levels or tissue-specific splicing profiles, and may play important ...
Jiang, Peng, Lam, Maggie PY, Lin, Lan, Lu, Zhi-Xiang, Park, Juw Won, Ping, Peipei, Wang, Jinkai, Xing, Yi   +7 more
core   +1 more source