Results 61 to 70 of about 1,508,590 (281)

The Integrative Studies on the Functional A-to-I RNA Editing Events in Human Cancers

Genomics, Proteomics & Bioinformatics, 2023
Adenosine-to-inosine (A-to-I) RNA editing, constituting nearly 90% of all RNA editing events in humans, has been reported to contribute to the tumorigenesis in diverse cancers.
Sijia Wu, Zhiwei Fan, Pora Kim, Liyu Huang, Xiaobo Zhou   +4 more
doaj   +1 more source

Changes in Body Composition in Children and Young People Undergoing Treatment for Acute Lymphoblastic Leukemia: A Systematic Review and Meta‐Analysis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Ongoing evidence indicates increased risk of sarcopenic obesity among children and young people (CYP) with acute lymphoblastic leukemia (ALL), often beginning early in treatment, persisting into survivorship. This review evaluates current literature on body composition in CYP with ALL during and after treatment.
Lina A. Zahed, Raquel Revuelta Iniesta, Mary Fewtrell, Julie Lanigan, Breeana Gardiner, Graeme O'Connor   +5 more
wiley   +1 more source

Genomic Positional Dissection of RNA Editomes in Tumor and Normal Samples

Frontiers in Genetics, 2019
RNA editing is phenomenon that occurs in both protein coding and non-coding RNAs. Increasing evidence have shown that adenosine-to-inosine RNA editing can potentially rendering substantial functional effects throughout the genome.
Michael Chigaev, Hui Yu, David C. Samuels, Quanhu Sheng, Olufunmilola Oyebamiji, Scott Ness, Wei Yue, Ying-yong Zhao, Yan Guo   +8 more
doaj   +1 more source

A nomogram based on A-to-I RNA editing predicting overall survival of patients with lung squamous carcinoma

BMC Cancer, 2022
Background Adenosine-to-inosine RNA editing (ATIRE) is characterized as non-mutational epigenetic reprogramming hallmark of cancer, while little is known about its predictive role in cancer survival.
Li Liu, Jun Liu, Xiaoliang Deng, Li Tu, Zhuxiang Zhao, Chenli Xie, Lei Yang   +6 more
doaj   +1 more source

Patient‐Level Barriers and Facilitators to Inpatient Physical Therapy in Adolescents and Young Adults With a Hematological Malignancy: A Qualitative Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Despite their increased risk for functional impairment resulting from cancer and its treatments, few adolescents and young adults (AYAs) with a hematological malignancy receive the recommended or therapeutic dose of exercise per week during inpatient hospitalizations.
Jennifer A. Kelleher, Jennifer L. Bernstein, Katia M. Crisler, Julia K. Herriott, Kimberly L. Klages, Robin E. Norris, Mariann L. Strenk, Sarah E. Bills, Meghan E. McGrady   +8 more
wiley   +1 more source

Clinical Characteristics and Prognostic Risk Factors for Pediatric B‐Cell Lymphoblastic Lymphoma: A Multicenter Retrospective Cohort Study for China Net Childhood Lymphoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background B‐cell lymphoblastic lymphoma (B‐LBL) represents a rare variety of non‐Hodgkin lymphoma, with limited research on its biology, progression, and management. Methods A retrospective analysis was performed on the clinical characteristics of 256 patients aged ≤18 years who received treatment under the China Net Childhood Lymphoma (CNCL)‐
Zhijuan Liu, Jian Wang, Ling Jin, Yanlong Duan, Fu Li, Yueping Jia, Leping Zhang, Xiaojun Yuan, Wei Liu, Ying Liu, Ansheng Liu, Mincui Zheng, Yunpeng Dai, Lian Jiang, Lirong Sun, Xiaowen Zhai, Rong Liu, Chunju Zhou, Zifen Gao, Yonghong Zhang, Xiaomei Yang   +20 more
wiley   +1 more source

Evolutionarily significant A-to-I RNA editing events originated through G-to-A mutations in primates

Genome Biology, 2019
BackgroundRecent studies have revealed thousands of A-to-I RNA editing events in primates, but the origination and general functions of these events are not well addressed.ResultsHere, we perform a comparative editome study in human and rhesus macaque ...
Ni A. An, Wanqiu Ding, Xinzhuang Yang, Jiguang Peng, B. He, Qing Sunny Shen, Fujian Lu, Aibin He, Yong E. Zhang, B. Tan, Jia-Yu Chen, Chuan-Yun Li   +11 more
semanticscholar   +2 more sources

The growth, development and infection process of the plant pathogen Fusarium

Plant Signaling & Behavior
The genus Fusarium includes some of the most detrimental pathogenic fungi to crops, significantly impacting cereal growth and food production. It causes devastating diseases such as banana wilt caused by Fusarium oxysporum and Fusarium head blight caused
Zhuo Li, Fengying He, Xiaotong Gai, Hongyao Zhu, Shidao He, Yuan Hu Xuan, Luchao Bai   +6 more
doaj   +1 more source

Intraoperative Collection of Ascitic Fluid With Intra‐ or Postoperative Reinfusion in Ovarian Cancer: Safety and Feasibility of a Roller Pumping Method

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Patients with ovarian cancer often present with massive ascites, leading to significant protein loss during surgical procedures. Although cell‐free concentrated ascites reinfusion therapy (CART) is used in palliative settings to mitigate protein loss, its application in intraoperative settings remains unexplored.
Yutaka Yoneoka, Tsukuru Amano, Akimasa Takahashi, Mari Deguchi, Hiroyuki Yamanaka, Yuji Tanaka, Shunichiro Tsuji, Takashi Murakami   +7 more
wiley   +1 more source

Conserved A-to-I RNA editing with non-conserved recoding expands the candidates of functional editing sites

Fly
Adenosine-to-inosine (A-to-I) RNA editing recodes the genome and confers flexibility for the organisms to adapt to the environment. It is believed that RNA recoding sites are well suited for facilitating adaptive evolution by increasing the proteomic ...
Yuange Duan, Ling Ma, Tianyou Zhao, Jiyao Liu, Caiqing Zheng, Fan Song, Li Tian, Wanzhi Cai, Hu Li   +8 more
doaj   +1 more source