Results 191 to 200 of about 584,058 (291)

Development of the Site-directed RNA Editing Utilizing Intracellular A-to-I RNA Editing

Development of the Site-directed RNA Editing Utilizing Intracellular A-to-I RNA Editing
2020
openaire  

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

ATTIC is an integrated approach for predicting A-to-I RNA editing sites in three species. [PDF]

Brief Bioinform, 2023
Chen R, Li F, Guo X, Bi Y, Li C, Pan S, Coin LJM, Song J.   +7 more
europepmc   +1 more source

Nomogram Based on A-To-I RNA Editing for Predicting Overall Survival in Patients With Breast Cancer. [PDF]

J Cell Mol Med
Zhang Y, Zhou J, Li H, Chai D, Lian B, Liu Y, Guo L, Li J.   +7 more
europepmc   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

The Landscape and Regulatory Determinants of A-to-I RNA Editing in Escherichia coli and Pseudomonas aeruginosa Isolated From Patients With Urinary Tract and Ear Infections. [PDF]

J Infect Dis
Elias E, Keidar-Friedman D, Sorek N, Raz O, Tamir SO, Aspit L, Bar Yaacov D.   +6 more
europepmc   +1 more source

A-to-I RNA Editing in Klebsiella pneumoniae Regulates Quorum Sensing and Affects Cell Growth and Virulence. [PDF]

Adv Sci (Weinh), 2023
Yang XZ, Sun TS, Jia PY, Li SJ, Li XG, Shi Y, Li X, Gao H, Yin H, Jia XM, Yang Q.   +10 more
europepmc   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

A-to-I RNA editing impairs miR-376b-3p repression of RYBP in skeletal muscle satellite cells. [PDF]

J Biol Chem
Xu X, Wei C, Zeng P, Zhan S, Dai D, Li L, Zhang H.   +6 more
europepmc   +1 more source