Results 101 to 110 of about 66,837 (297)

Hijacking Multivesicular Bodies Enables Long-Term and Exosome-Mediated Long-Distance Action of Anthrax Toxin

Cell Reports, 2013
Anthrax lethal toxin is a classical AB toxin comprised of two components: protective antigen (PA) and lethal factor (LF). Here, we show that following assembly and endocytosis, PA forms a channel that translocates LF, not only into the cytosol, but also ...
Laurence Abrami, Lucia Brandi, Mahtab Moayeri, Michael J. Brown, Bryan A. Krantz, Stephen H. Leppla, F. Gisou van der Goot   +6 more
doaj   +1 more source

Biodegradable Chitosan Films as Green Resists for Gold Nanowires Fabrication Through AFM‐Based Nanolithography

Advanced Materials Interfaces, EarlyView.
Schematic illustration of a sustainable nanofabrication process: chitosan derived from natural sources is used as a biodegradable thin film resist, patterned via Constant Pulse‐Assisted Force Lithography (CP‐AFL) to create tunable nanogrooves. These grooves template gold nanowire formation, enabling high‐resolution nanopatterning under ambient ...
Paolo Pellegrino, Lorenzo Vincenti, Isabella Farella, Valeria De Matteis, Mariafrancesca Cascione, Annalisa Bianco, Fabio Quaranta, Rosaria Rinaldi   +7 more
wiley   +1 more source

Interface‐Engineered Binary Framework Composites: Advancing Porous Materials for Precision Medicine

Advanced Materials Interfaces, EarlyView.
Binary framework composites integrate two complementary porous architectures into a unified platform, enabling multifunctional design, enhanced structural tunability, and improved physicochemical performance. By combining high surface area, ordered porosity, interfacial synergy, and versatile functionalization, these hybrid materials offer new ...
Navid Rabiee, Mohammad Rabiee, Mohammad Akrami‐Hasan‐Kohal, Sidi A. Bencherif   +3 more
wiley   +1 more source

Bacterial mutants devoid of AB type exotoxin by causing deficiency of toxin B-subunit and use THEREOF

, 2011
본 발명은 AB 타입 세균 독소(AB5 toxin)의 톡신 B-서브유닛(toxin B-subunit)이 결손된 것을 특징으로 하는 AB 타입 세균 독소가 결여된 균주 및 이의 용도에 관한 것으로, 더욱 상세하게는, 독성을 보유하는 하나의 A-서브유닛과 세포수용체와 결합하는 한 개 또는 다수의 B-서브유닛 단백질들이 결합하여 하나의 톡신 집합체(holotoxin)를 구성하는 AB-타입의 세균 독소(bacterial exotoxin)를 산생하는 병원성 ...
김상현, 장규태, 이용훈, 허재원, 김선욱, 김익균, 유수향, 이상래   +7 more
core  

Immunization of Mice with Anthrax Protective Antigen Limits Cardiotoxicity but Not Hepatotoxicity Following Lethal Toxin Challenge

Toxins, 2015
Protective immunity against anthrax is inferred from measurement of vaccine antigen-specific neutralizing antibody titers in serum samples. In animal models, in vivo challenges with toxin and/or spores can also be performed.
T. Scott Devera, Dawn K. Prusator, Sunil K. Joshi, Jimmy D. Ballard, Mark L. Lang   +4 more
doaj   +1 more source

Cornus Mas L. Seed‐Derived Biosorbent for Methylene Blue Removal: Surface Characterization and Biosorption Performance

Advanced Materials Interfaces, EarlyView.
Cornus mas L. seeds are transformed into a high‐performance biosorbent through chemical modification, effectively removing methylene blue from aqueous solutions. Comprehensive characterization and optimization reveal a maximum biosorption capacity of 71.71 mg g−1, establishing this sustainable, cost‐effective material as a promising solution for ...
Hakan Yıldız, Adem Necip, Arslan Yusuf Yüksel   +2 more
wiley   +1 more source

THE IMMUNOLOGY OF STAPHYLOCOCCAL ALPHA TOXIN.

, 1984
There are two types of antibodies to the alpha toxin of Staphylococcus aureus: the antibinding antibodies (AB-Ab) and the indirect hemagglutinating antibodies (IHA-Ab).
LO, CHING YEE.
core  

Impact of the nature and size of the polymeric backbone on the ability of heterobifunctional ligands to mediate Shiga toxin and serum amyloid P component ternary complex formation.

, 2011
Inhibition of AB(5)-type bacterial toxins can be achieved by heterobifunctional ligands (BAITs) that mediate assembly of supramolecular complexes involving the toxin's pentameric cell membrane-binding subunit and an endogenous protein, serum amyloid
Sadowska, J .M., Kitov, P. I., Narain, R., Deng, Z., Mulvey, G. L., Ahmed, M., Griener, T., Bundle, D. R., Armstrong, G. D., Paszkiewicz, E.   +9 more
core   +1 more source

Xenes for Sustainable Energy: A Roadmap From First‐Principles Design to Practical Deployment

Advanced Materials Interfaces, EarlyView.
Emerging 2D Xenes are advancing from theoretical predictions toward practical energy‐storage and conversion technologies through the integration of first‐principles modelling, experimental synthesis, electrochemical validation, and AI‐assisted materials design, enabling accelerated discovery of high‐performance and sustainable electrochemical systems ...
Onur Karaman, Ceren Karaman
wiley   +1 more source

A therapeutic chemical chaperone inhibits cholera intoxication and unfolding/translocation of the cholera toxin A1 subunit.

PLoS ONE, 2011
Cholera toxin (CT) travels as an intact AB(5) protein toxin from the cell surface to the endoplasmic reticulum (ER) of an intoxicated cell. In the ER, the catalytic A1 subunit dissociates from the rest of the toxin.
Michael Taylor, Tuhina Banerjee, Fernando Navarro-Garcia, Jazmin Huerta, Shane Massey, Mansfield Burlingame, Abhay H Pande, Suren A Tatulian, Ken Teter   +8 more
doaj   +1 more source