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Seronegative End-Stage Type I Achalasia With Megaesophagus in a Middle-Aged Woman From Central America: A Case Report. [PDF]
Dominguez DC, Richard J, El-Talla A.
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Developing Botulinum Toxin Drugs: Unexpected Challenges. [PDF]
Dressler D, Frevert J.
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Whole-genome analysis and phenotypic antimicrobial resistance of <i>Staphylococcus aureus</i> isolated from foods in Northern Kazakhstan. [PDF]
Kozhakhmetova SS +6 more
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Botulinum Toxin Injection to Treat Bruxism in a Child: A Case Report and Technique Description. [PDF]
Mallaguti FI +2 more
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The Clinical, Genetic, Psychosocial, and Care Landscape of X-Linked Dystonia-Parkinsonism in Filipino Men: A Scoping Review. [PDF]
Ramos MD +5 more
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Bacterial AB toxins and host–microbe interactions
2022AB toxins are protein virulence factors secreted by many bacterial pathogens, contributing to the pathogenicity of the cognate bacteria. AB toxins consist of two functionally distinct components: the enzymatic "A" component for pathogenicity and the receptor-binding "B" component for toxin delivery.
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AB5 toxins: structures and inhibitor design
Current Opinion in Structural Biology, 2000High-resolution crystal structures of AB(5) toxins in their native form or in complex with a variety of ligands have led to the structure-based design and discovery of inhibitors targeting different areas of the toxins. The most significant progress is the development of highly potent multivalent ligands that block binding of the toxins to their ...
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