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Developing Botulinum Toxin Drugs: Unexpected Challenges. [PDF]

open access: yesJ Neural Transm (Vienna)
Dressler D, Frevert J.
europepmc   +1 more source

Whole-genome analysis and phenotypic antimicrobial resistance of <i>Staphylococcus aureus</i> isolated from foods in Northern Kazakhstan. [PDF]

open access: yesFront Microbiol
Kozhakhmetova SS   +6 more
europepmc   +1 more source
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Bacterial AB toxins and host–microbe interactions

2022
AB toxins are protein virulence factors secreted by many bacterial pathogens, contributing to the pathogenicity of the cognate bacteria. AB toxins consist of two functionally distinct components: the enzymatic "A" component for pathogenicity and the receptor-binding "B" component for toxin delivery.
openaire   +2 more sources

AB5 toxins: structures and inhibitor design

Current Opinion in Structural Biology, 2000
High-resolution crystal structures of AB(5) toxins in their native form or in complex with a variety of ligands have led to the structure-based design and discovery of inhibitors targeting different areas of the toxins. The most significant progress is the development of highly potent multivalent ligands that block binding of the toxins to their ...
E, Fan   +3 more
openaire   +2 more sources

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