Results 101 to 110 of about 26,096 (220)

Severe Parkinson's Disease Linked to SNCA Locus Triplication Is Associated with Expression Changes in Platelets: A Case Report

Movement Disorders, EarlyView.
Susanna Jiménez‐Román, David Adamuz, Jorge Mena, Abril Tuset, Mar Mallo, Alex Menendez, Daniela Samaniego, Lourdes Ispierto, Dolores Vilas, Pau Pastor, Katrin Beyer   +10 more
wiley   +1 more source

Warburg redefined: Metabolites, mitochondria and macrophages in immune regulation

The Journal of Physiology, EarlyView.
Abstract figure legend Following pro‐inflammatory stimulation, macrophages undergo Warburg‐like metabolic rewiring that extends more than increased glycolysis. The non‐canonical functions of glycolytic enzymes and lactate accumulation control macrophage immune responses through multiple signalling pathways (a).
Yukun Min, Órlaith C. Henry, Luke A. J. O'Neill   +2 more
wiley   +1 more source

The ABCG2 Transporter Affects Plasma Levels, Tissue Distribution and Milk Secretion of Lumichrome, a Natural Derivative of Riboflavin [PDF]

[EN]The ABCG2 membrane transporter affects bioavailability and milk secretion of xenobiotics and natural compounds, including vitamins such as riboflavin.
Alicia Millán-García, Laura Álvarez-Fernández, Ana I. Álvarez, Blanco Paniagua, Esther, Merino Peláez, Gracia, Millán García, Alicia, Álvarez de Felipe, Ana Isabel, Esther Blanco-Paniagua, Álvarez Fernández, Laura, Gracia Merino   +9 more
core   +1 more source

SLCO1B1 and ABCG2 Gene Polymorphisms in a Thai Population

Pharmacogenomics and Personalized Medicine, 2020
Punyabhorn Rattanacheeworn,1,2 Monpat Chamnanphon,1 Siriwan Thongthip,3 Wonngarm Kittanamongkolchai,3 Natavudh Townamchai,1,4 Yingyos Avihingsanon,1,4 Udomsak Udomnilobol,5 Thomayant Prueksaritanont,5 Suree Jianmongkol,5,6 Pajaree Chariyavilaskul1,2 ...
Rattanacheeworn P, Chamnanphon M, Thongthip S, Kittanamongkolchai W, Townamchai N, Avihingsanon Y, Udomnilobol U, Prueksaritanont T, Jianmongkol S, Chariyavilaskul P   +9 more
doaj  

Estrogen induces cell proliferation by promoting ABCG2-mediated efflux in endometrial cancer cells

Biochemistry and Biophysics Reports, 2018
Recently, it has reported that overeating of lipid-food has led to increase the amount of estrogen in vivo and the incidence of endometrial carcinomas.
Takahiro Yaguchi, Takafumi Onishi
doaj   +1 more source

ABCG2 impairs the activity of the aurora kinase inhibitor tozasertib but not of alisertib. [PDF]

, 2015
BACKGROUND Recently, we have shown that the ATP-binding cassette (ABC) transporter ABCB1 interferes with the anti-cancer activity of the pan-aurora kinase inhibitor tozasertib (VX680, MK-0457) but not of the aurora kinase A and B inhibitor alisertib ...
Michaelis, Martin, Cinatl, Jindrich, Martin Michaelis, Michael Wiese, Martin Michaelis (23843), Michael Wiese (2236483), Jindrich Cinatl (23848), Rothweiler, Florian, Wiese, Michael, Selt, Florian, Jindrich Cinatl, Florian Rothweiler (637020), Florian Selt, Florian Rothweiler, Florian Selt (637019)   +14 more
core   +1 more source

Revisiting strategies to target ABC transporter-mediated drug resistance in CNS cancer

Cancer Biology & Medicine
A significant number of anticancer drugs fail to treat primary and metastatic brain tumors primarily because of the complex blood-brain barrier (BBB) and overexpression of ATP-binding cassette (ABC) transporters, which decrease drug penetration into the ...
Haneen Amawi, Alaa M. Hammad, F. Scott Hall, Noor Hussein, Aseel O. Rataan, Abeer Mrayyan, Taqwa Al-kofahi, Ali Hmedat, Charles R. Ashby, Amit K. Tiwari   +9 more
doaj   +1 more source

Protein expression of cancer stem cell markers ABCG2, podoplanin, and CD44 predicts early recurrence of oral squamous cell carcinoma: A study from Western India

Indian Journal of Pathology and Microbiology
Objectives: For oral squamous cell carcinoma (OSCC), we are likely at a juncture in clinical management, where the benefits of therapies are beginning to plateau.
Trupti I. Trivedi, Toral H. Mandaliya, Priti P. Trivedi   +2 more
doaj   +1 more source

PCI29732, a Bruton’s Tyrosine Kinase Inhibitor, Enhanced the Efficacy of Conventional Chemotherapeutic Agents in ABCG2-Overexpressing Cancer Cells

Cellular Physiology and Biochemistry, 2018
Background/Aims: Multidrug resistance (MDR) induced by the ABC transporter subfamily B member 1 (ABCB1) and subfamilyG member 2 (ABCG2) limits successful cancer chemotherapy and no commercially available MDR modulator is used in the clinic.
Chunlei Ge, Fang Wang, Chaochu Cui, Xiaodong Su, Kenneth Kin Wah To, Xiaokun Wang, Hui Zhang, Xin Song, Liwu Fu   +8 more
doaj   +1 more source

Alpinia oxyphylla Miq.: Chemical Constituents, Neuroprotective and Metabolic Effects, and Translational Challenges—A Review of Preclinical Evidence

Food Science &Nutrition, Volume 14, Issue 11, November 2026.
Alpinia oxyphylla Miq. (AOM), a medicinal and edible resource, contains diphenylheptanoids, polysaccharides, flavonoids, terpenoids, and phenolic acids. These constituents exert multi‐target synergistic effects by modulating neuroinflammation, oxidative stress, and the PI3K/Akt pathway, thereby improving Alzheimer's disease, Parkinson's disease, and ...
Ziyan Yang, Hemei Yuan, Dengyou Nie, Jun Sheng, Titi Liu, Huanhuan Xu   +5 more
wiley   +1 more source