BackgroundATP-binding cassette (ABC) proteins are transmembrane efflux pumps that play a role in Multi Drug Resistance. ABCG2 and ABCB1 have been suggested as important mediators of resistance to chemotherapy (CTx) in pancreatic cancer (PC).
Susy Shim +11 more
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人原发性肝癌细胞ABCG2+表型的检测、分离及其生物学特性的初步研究
目的检测人原发性肝癌ABCG2+亚群细胞并加以分离,对其生物学特性进行初步研究。方法通过PE-ABCG2单克隆抗体标记,流式细胞仪检测、分选ABCG2+细胞,体外培养后进行细胞周期、增殖活性和凋亡的检测。结果原发性肝癌细胞中存在ABCG2+表型,占细胞总数的1.3%;体外培养24 hours,ABCG2+表型有81.48%处于细胞周期的G0/G1期,non-ABCG2-表型为46.05%;ABCG2+表型凋亡率为11.5%,non-ABCG2-为27.9%;体外连续培养7天,ABCG2 ...
doaj
The JR blood group system: from discovery to the clinic. [PDF]
Ma X +7 more
europepmc +1 more source
Effects of ABCG2 dysfunction on hyperuricemia progression in premenopausal and postmenopausal women. [PDF]
Miyoshi Y +22 more
europepmc +1 more source
<i>ABCG2</i> Contributes to Multidrug Resistance and Aggressive Phenotypes Associated with ERK Signaling in Gastric Cancer. [PDF]
Türksoy Terzioğlu Ö, Terzioğlu G.
europepmc +1 more source
PrimaDORAC: An improved Web Interface for Rapid GAFF2 Parameter Assignment with ABCG2 Charge Models for Drug Design Applications. [PDF]
Procacci P.
europepmc +1 more source
ABCG2-autophagy regulatory axis in cancer stem cells: implication in cancer metastasis, recurrence and chemotherapy resistance. [PDF]
Zalpoor H +5 more
europepmc +1 more source
Antihyperuricemic Effect of Hawthorn Flavonoid Vitexin: LC-MS Analysis, Network Pharmacology, and In Vivo Verification of Molecular Mechanisms. [PDF]
Wu SY +11 more
europepmc +1 more source
ABCG2 Genetic Variability in Drug Exposure and Toxicity: Implications for Clinical Practice. [PDF]
Božina T +6 more
europepmc +1 more source
Obesity Triggers Dysregulation of Essential ABC Transporters in Rat Testis and Sperm. [PDF]
Szatmári P +3 more
europepmc +1 more source

