Results 21 to 30 of about 6,910 (195)
Statin use decreases coagulation in users of vitamin K antagonists [PDF]
Purpose: The purpose of the study is to determine the immediate and long-term effect of statins on coagulation in patients treated with vitamin K antagonists (VKAs). Methods: We selected patients on VKAs of two Dutch anticoagulation clinics who initiated
Biedermann, J.S. (Joseph) +5 more
core +4 more sources
Background and objectives: Patients with heart failure (HF) often present with non-valvular atrial fibrillation and require oral anticoagulation with coumarin anticoagulants such as acenocoumarol.
Rubén Ángel Martín-Sánchez +12 more
doaj +1 more source
Development of a clinical prediction model for an international normalised ratio ≥ 4·5 in hospitalised patients using vitamin K antagonists [PDF]
Vitamin K antagonists (VKAs) used for the prevention and treatment of thromboembolic disease, increase the risk of bleeding complications. We developed and validated a model to predict the risk of an international normalised ratio (INR) ≥ 4·5 during a ...
Bemt, P.M.L.A. (Patricia) van den +6 more
core +1 more source
Visualisation of thrombus in the main pulmonary artery through two-dimensional transthoracic echocardiography (TTE) without cardiovascular instability is rare. We report a unique case of echocardiographically diagnosed acute pulmonary embolism (PE) in an
Karanam Gowrinath, K Padmanabha Kamath
doaj +1 more source
Aim: Healthcare resources usage and costs associated to nonvalvular atrial fibrillation (NVAF) were analyzed in Spain. Methods: This is an observational and retrospective study on patients with NVAF who started their treatment with apixaban or ...
Josep Comin Colet +6 more
doaj +1 more source
The risk of overanticoagulation in patients with heart failure on coumarin anticoagulants [PDF]
Heart failure has been identified as a risk factor for increased coumarin anticoagulant responsiveness in several small-scale experiments. Epidemiological studies quantifying the risk of overanticoagulation by heart failure in a non-selected population ...
Bleumink, G.S. (Gysèle) +5 more
core +1 more source
BackgroundVitamin K antagonists (VKA) are used as prophylaxis for thromboembolic events in patients with cardiovascular diseases. The most common VKA are warfarin and acenocoumarol.
Angela Roco +19 more
doaj +1 more source
Do antithrombotic drugs have a role in migraine prevention? A systematic review. [PDF]
Abstract Objectives To explore the available evidence on the role of antithrombotics as migraine preventive medication. Background In clinical practice, the use of antithrombotic drugs in individuals with migraine is sometimes considered, especially in the case of frequent auras, association with patent foramen ovale, or prothrombotic states.
De Santis F +7 more
europepmc +2 more sources
The c.-1639G > A polymorphism of the VKORC1 gene is a major determinant of the response to acenocoumarol in anticoagulated patients [PDF]
Much of the variability in the sensitivity to warfarin in anticoagulated patients is associated with the c.-1639G > A polymorphism of the vitamin K-epoxide reductase (VKORC1) gene.
Alberca, I. (Ignacio) +4 more
core +1 more source
Identification and weighting of the most critical "real-life” drug-drug interactions with acenocoumarol in a tertiary care hospital [PDF]
Purpose: The objective of this study was to identify the most clinically relevant drug-drug interactions (DDIs) at risk of affecting acenocoumarol safety in our tertiary care university hospital, a 2,000 bed institution.
Boehlen, F. +6 more
core +4 more sources

