Results 101 to 110 of about 3,165 (181)
Translational Oncology, 2015 Inflammatory breast cancer (IBC) is an aggressive and invasive tumor, accounting for 2.5% of all breast cancer cases, and characterized by rapid progression, regional and distant metastases, younger age of onset, and lower overall survival.
Roberto Wurth +6 more
doaj +1 more source
HPV6‐Induced Gene Expression Signature in Recurrent Respiratory Papillomatosis
The Laryngoscope, Volume 135, Issue 10, Page 3732-3739, October 2025.Using the conditional reprogramming method, we established a cell culture model of recurrent respiratory papillomatosis and analyzed gene expression. Genes related to human papillomavirus 6 expression were identified, including inflammatory genes (e.g., CTSS, CFB), oncogenic genes (e.g., CEACAM5, CEACAM6), and glycosylation‐associated genes (e.g ...
Naoyuki Matsumoto +10 more
wiley +1 more source
Small Science, Volume 5, Issue 10, October 2025.Nanotopography improves the piezoelectric properties of BaTiO3 due to decreased Young's modulus. Nanotopography‐mediated mechanical stress dominantly boosts osteogenesis and angiogenesis via Piezo2/Piezo1/Ca2+ signaling. Augmented electric stimulation improves mechanical stress‐mediated osteogenic/angiogenic enhancement via PI3K/AKT/mTOR/GSK3β‐1 ...
Jingyan Huang +7 more
wiley +1 more source
MedComm, Volume 6, Issue 9, September 2025.Single‐cell RNA sequencing of EGFR‐TKI‐resistant NSCLC reveals distinct roles of VEGFA and VEGFC in ABCP therapy response. VEGFA drives tumor proliferation in responders, while VEGFC promotes resistance through TME interaction, FGF signaling, and YAP‐TAZ regulation.
Sehwa Hong +12 more
wiley +1 more source
Electroacupuncture Promotes Remyelination after Cuprizone Treatment by Enhancing Myelin Debris Clearance [PDF]
, 2017 Promoting remyelination is crucial for patients with demyelinating diseases including multiple sclerosis. However, it is still a circuitous conundrum finding a practical remyelinating therapy. Electroacupuncture (EA), originating from traditional Chinese
Gencheng Wu +5 more
core +1 more source
Decreased ACKR3 (CXCR7) function causes oculomotor synkinesis in mice and humans
Human Molecular Genetics, 2019 Abstract Oculomotor synkinesis is the involuntary movement of the eyes or eyelids with a voluntary attempt at a different movement. The chemokine receptor CXCR4 and its ligand CXCL12 regulate oculomotor nerve development; mice with loss of either molecule have oculomotor synkinesis.
Mary C, Whitman +11 more
openaire +3 more sources
Frontiers in Immunology, 2015 CXCR4 and its ligand CXCL12 mediate the homing of progenitor cells in the bone marrow and their recruitment to sites of injury, as well as affect processes such as cell arrest, survival and angiogenesis.
Lukas ePawig +4 more
doaj +1 more source
Genetic Risk Factors for Atypical Femoral Fractures (AFFs): A Systematic Review [PDF]
, 2018 Atypical femoral fractures (AFFs) are uncommon and have been associated particularly with long-term antiresorptive therapy, including bisphosphonates. Although the pathogenesis of AFFs is unknown, their identification in bisphosphonate-naïve individuals ...
Ebeling, P. (Peter) +5 more
core +3 more sources
MIF-ACKR3 causes irreversible fat loss by impairing adipogenesis in cancer cachexia
Cell MetabolismBoth exercise and cancer can cause adipose tissue shrinkage. However, only cancer-associated weight loss, namely cachexia, is characterized by profound adipose inflammation and fibrosis. Here, we identified tumor-secreted macrophage migration inhibitory factor (MIF) as a major driver that skews the differentiation of adipose stem and progenitor cells ...
Qionghua, Cui +11 more
openaire +2 more sources
Frontiers in Immunology, 2018 CXCL12 is a chemotactic cytokine that attracts many different cell types for homeostasis and during inflammation. Under stress conditions, macrophages and granulocytes produce factors such as peroxynitrite as a consequence of their oxidative response ...
Rik Janssens +19 more
doaj +1 more source