Development of a set of bacterial engineered glycoconjugates as novel serogroup-specific antigens for the serodiagnosis of Escherichia coli O26, O111, O103 and O45 infections associated to hemolytic uremic syndrome [PDF]
Microbial Cell FactoriesHemolytic uremic syndrome associated to Shiga toxin-producing Escherichia coli infection (STEC-HUS) is a life-threatening condition characterized by microangiopathic hemolytic anemia, thrombocytopenia, and acute kidney failure. Among STEC, E.
Ana J. Caillava +9 more
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Expression of the Fluoroquinolones Efflux Pump Genes acrA and mdfA in Urinary Escherichia coli Isolates [PDF]
Polish Journal of Microbiology, 2017 Escherichia coli is one of the most frequent causes of urinary tract infections. Efflux system overexpression is reported to contribute to E. coli resistance to several antibiotics. Our aim in this study was to investigate the relation between antibiotic
Sarah M. Abdelhamid, Rania R. Abozahra
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Microbiology SpectrumWhole-genome sequencing of a clinical tigecycline non-susceptible Klebsiella pneumoniae strain reveals a novel T188A mutation in AcrA, raising awareness on its role in tigecycline resistance.
Hai Xu, Mingyu Wang, Ling Li
exaly +3 more sources
Detection of AcrA and AcrB Efflux Pumps in Multidrug-Resistant Klebsiella pneumonia that Isolated from Wounds Infection Patients in Al-Diwaniyah Province [PDF]
Archives of Razi Institute, 2023 Many infections produced by multidrug-resistant (MDR) Klebsiella pneumoniae are the main cause of death and treatment restrictions worldwide. In K. pneumoniae, the efflux pump system is dangerous in drug resistance.
S Abid Fazaa ALmiyah
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Efflux Pump-Binding 4(3-Aminocyclobutyl)Pyrimidin-2-Amines Are Colloidal Aggregators
Biomolecules, 2023 Efflux pumps are a relevant factor in antimicrobial resistance. In E. coli, the tripartite efflux pump AcrAB-TolC removes a chemically diverse set of antibiotics from the bacterium.
Tania Szal +8 more
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Conformational restriction shapes the inhibition of a multidrug efflux adaptor protein
Nature Communications, 2023 Membrane efflux pumps play a major role in bacterial multidrug resistance. The tripartite multidrug efflux pump system from Escherichia coli, AcrAB-TolC, is a target for inhibition to lessen resistance development and restore antibiotic efficacy, with ...
Benjamin Russell Lewis +11 more
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Корпоративные финансы, 2017 This research addresses the problem of pension savings and pension reserves management efficiency analysis of the whole Russian pension system and non-state pension funds.
Yury Nogin
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Energies, 2013 A novel artificial cobweb routing algorithm (ACRA) for routing the tree-type physical topology of a low-voltage distribution network in a smart grid is proposed and analyzed in this paper.
Dianguo Xu +3 more
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Membrane fusion proteins of type I secretion system and tripartite efflux pumps share a binding motif for TolC in gram-negative bacteria. [PDF]
PLoS ONE, 2012 The Hly translocator complex of Escherichia coli catalyzes type I secretion of the toxin hemolysin A (HlyA). In this complex, HlyB is an inner membrane ABC (ATP Binding Cassette)-type transporter, TolC is an outer membrane channel protein, and HlyD is a ...
Minho Lee +5 more
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Children, 2013 I am very excited about the upcoming launch of Children, a journal dedicated to the streamlined yet scientifically rigorous electronic dissemination of peer-reviewed science related to childhood health and disease in developed and developing countries ...
Sari Acra
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