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Actin cytoskeleton in angiogenesis

open access: yesBiology Open, 2022
ABSTRACTActin, one of the most abundant intracellular proteins in mammalian cells, is a critical regulator of cell shape and polarity, migration, cell division, and transcriptional response. Angiogenesis, or the formation of new blood vessels in the body is a well-coordinated multi-step process.
Nidhi Yadunandanan Nair   +5 more
doaj   +3 more sources

Regulation of the Actin Cytoskeleton in Podocytes [PDF]

open access: yesCells, 2020
Podocytes are an integral part of the glomerular filtration barrier, a structure that prevents filtration of large proteins and macromolecules into the urine.
Judith Blaine, James Dylewski
doaj   +3 more sources

NPFs-mediated actin cytoskeleton: a new viewpoint on autophagy regulation [PDF]

open access: yesCell Communication and Signaling
Macroautophagy/autophagy is a lysosome-dependent catabolic process induced by various cellular stress conditions, maintaining the homeostasis of cells, tissues and organs.
Yuan Dong, Chengshi Quan
doaj   +2 more sources

Intracellular tension sensor reveals mechanical anisotropy of the actin cytoskeleton [PDF]

open access: yesNature Communications, 2023
The filamentous actin (F-actin) cytoskeleton is a composite material consisting of cortical actin and bundled F-actin stress fibers, which together mediate the mechanical behaviors of the cell, from cell division to cell migration. However, as mechanical
Sorosh Amiri   +6 more
doaj   +2 more sources

Actin Cytoskeleton and Integrin Components Are Interdependent for Slit Diaphragm Maintenance in Drosophila Nephrocytes [PDF]

open access: yesCells
In nephrotic syndrome, the podocyte filtration structures are damaged in a process called foot process effacement. This is mediated by the actin cytoskeleton; however, which actins are involved and how they interact with other filtration components, like
Megan Delaney   +4 more
doaj   +2 more sources

The role of actin cytoskeleton CFL1 and ADF/cofilin superfamily in inflammatory response [PDF]

open access: yesFrontiers in Molecular Biosciences
Actin remodeling proteins are important in immune diseases and regulate cell cytoskeletal responses. These responses play a pivotal role in maintaining the delicate balance of biological events, protecting against acute or chronic inflammation in a range
Jianxiao Xing   +5 more
doaj   +2 more sources

Regulation of actin cytoskeleton via photolithographic micropatterning

open access: yesJournal of Innovative Optical Health Sciences, 2023
Actin cytoskeleton plays crucial roles in various cellular functions. Extracellular matrix (ECM) can modulate cell morphology by remodeling the internal cytoskeleton.
Fulin Xing   +9 more
doaj   +1 more source

Influence of ROCK Pathway Manipulation on the Actin Cytoskeleton Height

open access: yesCells, 2022
The actin cytoskeleton with its dynamic properties serves as the driving force for the movement and division of cells and gives the cell shape and structure. Disorders in the actin cytoskeleton occur in many diseases.
Carolin Grandy   +3 more
doaj   +1 more source

The yeast actin cytoskeleton [PDF]

open access: yesFEMS Microbiology Reviews, 2014
The actin cytoskeleton is a complex network of dynamic polymers, which plays an important role in various fundamental cellular processes, including maintenance of cell shape, polarity, cell division, cell migration, endocytosis, vesicular trafficking, and mechanosensation. Precise spatiotemporal assembly and disassembly of actin structures is regulated
Mithilesh Mishra   +2 more
openaire   +3 more sources

Actin Cytoskeleton Role in the Maintenance of Neuronal Morphology and Long-Term Memory

open access: yesCells, 2021
Evidence indicates that long-term memory formation creates long-lasting changes in neuronal morphology within a specific neuronal network that forms the memory trace.
Raphael Lamprecht
doaj   +1 more source

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