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Actin cytoskeleton in angiogenesis
ABSTRACTActin, one of the most abundant intracellular proteins in mammalian cells, is a critical regulator of cell shape and polarity, migration, cell division, and transcriptional response. Angiogenesis, or the formation of new blood vessels in the body is a well-coordinated multi-step process.
Nidhi Yadunandanan Nair +5 more
doaj +3 more sources
Actin Cytoskeleton: A Team Effort during Actin Assembly [PDF]
Two recent studies highlight how tandems of previously described actin nucleators collaborate to produce new actin filaments. One key player in these collaborations is formin, which appears to function as a modulator of filament elongation.
Laurent Blanchoin, Alphée Michelot
openalex +5 more sources
The role of actin cytoskeleton component Arp2/3 in inflammatory response [PDF]
Actin regulatory protein plays an important role in immune-related diseases and affects cellular behavior by regulating the dynamic changes of the cytoskeleton.
Jianxiao Xing +6 more
doaj +2 more sources
Actin cytoskeleton regulates Hippo signaling. [PDF]
Hippo pathway controls the organ size by modulating cell proliferation and apoptosis. However, the upstream regulation of hippo signaling by actin cytoskeleton is not clear.
Pradeep Reddy +3 more
doaj +4 more sources
The role of actin cytoskeleton CFL1 and ADF/cofilin superfamily in inflammatory response [PDF]
Actin remodeling proteins are important in immune diseases and regulate cell cytoskeletal responses. These responses play a pivotal role in maintaining the delicate balance of biological events, protecting against acute or chronic inflammation in a range
Jianxiao Xing +5 more
doaj +2 more sources
Actin Cytoskeleton and Integrin Components Are Interdependent for Slit Diaphragm Maintenance in Drosophila Nephrocytes [PDF]
In nephrotic syndrome, the podocyte filtration structures are damaged in a process called foot process effacement. This is mediated by the actin cytoskeleton; however, which actins are involved and how they interact with other filtration components, like
Megan Delaney +4 more
doaj +2 more sources
Theory of active self-organization of dense nematic structures in the actin cytoskeleton. [PDF]
Mirza W +5 more
europepmc +2 more sources
Regulation of actin cytoskeleton via photolithographic micropatterning
Actin cytoskeleton plays crucial roles in various cellular functions. Extracellular matrix (ECM) can modulate cell morphology by remodeling the internal cytoskeleton.
Fulin Xing +9 more
doaj +1 more source
Influence of ROCK Pathway Manipulation on the Actin Cytoskeleton Height
The actin cytoskeleton with its dynamic properties serves as the driving force for the movement and division of cells and gives the cell shape and structure. Disorders in the actin cytoskeleton occur in many diseases.
Carolin Grandy +3 more
doaj +1 more source
Previous work from us and others has suggested that cholesterol is an important lipid in the context of the organization of the actin cytoskeleton.
Parijat Sarkar +3 more
doaj +1 more source

