Activin A is Not a Reliable Prognostic Biomarker For Bilirubin Induced Neurotoxicity in Neonates [PDF]
Pediatric Sciences Journal, 2022 Background: Bilirubin induced neurological dysfunction (BIND) remains an important cause of disability in developing countries. Although high total serum bilirubin (TSB) is the main instigator for BIND, different babies may have different neurological ...
Esraa A. El Mazzahy +4 more
doaj +1 more source
Constitutively active FOXO1 diminishes activin induction of Fshb transcription in immortalized gonadotropes. [PDF]
, 2014 In the present study, we investigate whether the FOXO1 transcription factor modulates activin signaling in pituitary gonadotropes. Our studies show that overexpression of constitutively active FOXO1 decreases activin induction of murine Fshb gene ...
Arriola, David J +4 more
core +14 more sources
Improved Production of Recombinant Human Activin A in Escherichia coli [PDF]
Journal of Sciences, Islamic Republic of Iran, 2021 Activin A is a member of transforming growth factor β (TGF-β) superfamily. It plays numerous roles in the body such as cell growth regulation and differentiation, wound repairing and modulation of inflammatory responses.
Zahra Hajihassan +2 more
doaj +1 more source
ارزیابی تأثیر فاکتور رشد Activin A و کوچک مولکول IDE1 در تکثیر و خودنوزایی سلولهای زایای بدوی جوجه در شرایط کشت آزمایشگاهی [PDF]
زیستشناسی کاربردی, 2023 مقدمه: چالش اصلی سلولها سلولهای زایای بدوی (PGC)، عدم تکثیر و خودنوزایی آنها در محیط کشت است. یک روش برای القای پرتوانی سلولهای PGC، دستکاری مسیرهای پیامرسانی درونسلولی ازجمله TGF-β است که استفاده از فاکتورهای رشد و کوچک مولکولها یکی از روشهای ...
معصومه زارع +3 more
doaj +1 more source
Activin A regulates activation of mouse neutrophils by Smad3 signalling [PDF]
Open Biology, 2017 Activin A, a member of the transforming growth factor beta superfamily, acts as a pro-inflammatory factor in acute phase response, and influences the pathological progress of neutrophil-mediated disease.
Yan Qi +5 more
doaj +1 more source
Enhanced Expression of Recombinant Activin A in Escherichia coli by Optimization of Induction Parameters [PDF]
Journal of Sciences, Islamic Republic of Iran, 2018 Activin A is a member of the transforming growth factor β super family. Because of its extensive clinical usages, its recombinant production is beneficial. In this study, activin A was expressed in E. coli using the pET 21a expression vector.
Z. Hajihassan, N. Biroonro
doaj +1 more source
Serum levels of Activin A: Marker of insulin resistance and cardiovascular risk in prediabetics
Journal of Family Medicine and Primary Care, 2022 Background: A substantial proportion of health burden in diabetic individuals can be attributed to cardiovascular complications. The increasing risk of cardiovascular complications along the spectrum of dysglycemia warrants the need to devise novel ...
Ajay Chauhan +3 more
doaj +1 more source
Activin-A: active in inflammation in COPD [PDF]
European Respiratory Journal, 2014 Chronic obstructive pulmonary disease (COPD) is characterised by irreversible airflow limitation in which chronic inflammation of the airways plays a major role. The persistent inflammation is triggered by inhaled toxic substances, such as cigarette smoke.
Tania, Navessa P. +2 more
openaire +2 more sources
Laboratory Markers in the Prediction of Premature Birth
Journal of Preventive, Diagnostic and Treatment Strategies in Medicine, 2023 The problem of premature birth (PB) remains topical for the practicing obstetrician-gynecologist. The study of marker proteins indicating an increased risk of PB is one of the relevant areas of interest in modern obstetrics.
Evgenia Igorevna Popova +5 more
doaj +1 more source
A Novel Signal Peptide Derived from Bacillus Licheniformis α-Amylase Efficiently Targets Recombinant Human Activin A to the Periplasm of Escherichia coli [PDF]
Journal of Cell and Molecular Research, 2018 Human activin A is a member of the transforming growth factor-β superfamily consists of two similar beta subunits. Activin A is expressed by different cells and displays numerous biological activities such as control of neuronal cell proliferation and ...
Zahra Hajihassan +2 more
doaj +1 more source