Results 31 to 40 of about 20,228 (237)
Substantial Increases Occur in Serum Activins and Follistatin during Lung Transplantation. [PDF]
PLoS ONE, 2016 Lung transplantation exposes the donated lung to a period of anoxia. Re-establishing the circulation after ischemia stimulates inflammation causing organ damage.
David M de Kretser +7 more
doaj +1 more source
Activin/TGFβ and BMP crosstalk determines digit chondrogenesis [PDF]
, 2008 The progress zone (PZ) is a specialized area at the distal margin of the developing limb where mesodermal cells are kept in proliferation and undifferentiated, allowing limb outgrowth.
1000010205429 +5 more
core +11 more sources
iScience, 2021 Summary: Targeting the signaling pathway of growth differentiation factor 8 (GDF8), also known as myostatin, has been regarded as a promising strategy to increase muscle mass in the elderly and in patients.
Takayuki Ozawa +7 more
doaj +1 more source
Treatment with soluble activin type IIB-receptor improves bone mass and strength in a mouse model of Duchenne muscular dystrophy [PDF]
, 2017 Background: Inhibition of activin/myostatin pathway has emerged as a novel approach to increase muscle mass and bone strength. Duchenne muscular dystrophy (DMD) is a neuromuscular disorder that leads to progressive muscle degeneration and also high ...
Heikinheimo, Kristiina +8 more
core +1 more source
Role of Activins in Hepcidin Regulation during Malaria
Infection and Immunity, 2017 Epidemiological observations have linked increased host iron with malaria susceptibility, and perturbed iron handling has been hypothesized to contribute to the potentially life-threatening anemia that may accompany blood-stage malaria infection.
Natasha Spottiswoode +10 more
semanticscholar +1 more source
BMC Biology, 2022 Background Activins and bone morphogenetic proteins (BMPs) play critical, sometimes opposing roles, in multiple physiological and pathological processes and diseases.
Szabina Szófia Szilágyi +4 more
doaj +1 more source
The orphan ligand, activin C, signals through activin receptor-like kinase 7
eLife, 2022 Activin ligands are formed from two disulfide-linked inhibin β (Inhβ) subunit chains. They exist as homodimeric proteins, as in the case of activin A (ActA; InhβA/InhβA) or activin C (ActC; InhβC/InhβC), or as heterodimers, as with activin AC (ActAC ...
Erich J Goebel +8 more
doaj +1 more source
Smad signalling in the ovary [PDF]
, 2006 has now been a decade since the first discovery of the intracellular Smad proteins, the downstream signalling molecules of one of the most important growth factor families in the animal kingdom, the transforming growth factor beta (TGF-beta) superfamily.
Jeffrey, Luke A. +3 more
core +3 more sources
TLR3 Deficiency Leads to a Dysregulation in the Global Gene-Expression Profile in Murine Oviduct Epithelial Cells Infected with Chlamydia muridarum [PDF]
, 2019 OBJECTIVE Describe the implementation and effects of Mobile Acute Care for Elders (MACE) consultation at a Veterans Affairs Medical Center (VAMC). DESIGN Retrospective cohort analysis.
Derbigny, Wilbert A, Kumar, Ramesh
core +2 more sources
Structure and activation of pro-activin A
Nature Communications, 2016 Activins are members of the TGF-β family of growth factors that are processed from precursors into the mature proteins. Here, the authors use structural biology and biochemistry to examine the protein domain organisation and gain insights into the ...
Xuelu Wang +2 more
doaj +1 more source