Expressão de proteínas SMAD, mediadores da sinalização de TGF-beta/activina, em tecidos de tiroide humana [PDF]
OBJECTIVE: To investigate the expression of SMAD proteins in human thyroid tissues since the inactivation of TGF-β/activin signaling components is reported in several types of cancer.
EBINA, Kátia N. +7 more
core +2 more sources
Role of activins in embryo implantation and diagnosis of ectopic pregnancy: a review
Embryo implantation is a major prerequisite for the successful establishment of pregnancy. Ectopic implantation outside the intrauterine cavity and the development of ectopic pregnancy (EP) is a major cause of maternal morbidity and occasionally ...
Bassem Refaat
semanticscholar +1 more source
The impact of menopause on bone, zoledronic acid, and implications for breast cancer growth and metastasis [PDF]
Recent data from the AZURE, ABCSG-12, and ZO-FAST clinical trials have challenged our understanding of the potential anticancer activity of zoledronic acid (ZOL). Although the results of these studies may appear to be conflicting on the surface, a deeper
Arrington +104 more
core +1 more source
Activins and their related proteins in colon carcinogenesis: insights from early and advanced azoxymethane rat models of colon cancer [PDF]
BACKGROUND: Activin-A may exert pro- or anti-tumorigenic activities depending on cellular context. However, little is known about its role, or the other mature activin proteins, in colorectal carcinoma (CRC). This study measured the expression of activin
Adel Galal El-Shemi +5 more
core +1 more source
Background Toxicity of chemotherapy on skeletal muscles and the heart may significantly contribute to cancer cachexia, mortality, and decreased quality of life.
Juha J. Hulmi +9 more
doaj +1 more source
Differential expression of follistatin and FLRG in human breast proliferative disorders
Background Activins are growth factors acting on cell growth and differentiation. Activins are expressed in high grade breast tumors and they display an antiproliferative effect inducing G0/G1 cell cycle arrest in breast cancer cell lines.
Amaral Vania F +11 more
doaj +1 more source
The activins and inhibins are glycoproteins with a role in the follicular development of vertebrates, that are found in follicular fluid and somatic follicular cells, with a different pattern among taxa.
N.B. Cruz-Cano +5 more
doaj +1 more source
Recognizing menopause in women with amenorrhea induced by cytotoxic chemotherapy for endocrine-responsive early breast cancer. [PDF]
Cytotoxic anticancer treatment may induce amenorrhea or menopause to a variable extent. These side effects may not only impair or impede fertility but also cause sexual dysfunction, bone loss, and menopausal symptoms, with a strikingly negative effect on
Appetecchia, M +5 more
core +1 more source
Prognostic value of activin A level in patients with advanced lung cancer and sarcopenia
The aim of this work is to determine the prognostic role of activin A in patients with advanced lung cancer and sarcopenia. Materials and methods.
V. V. Kechedzhyiev
doaj +1 more source
Aims. To measure the effect of pegylated interferon-α therapy on serum activin-A, activin-B, and follistatin and their correlation with viral load and liver fibrosis in chronic hepatitis C (CHC). Methods.
Bassem Refaat +3 more
doaj +1 more source

