Results 111 to 120 of about 15,625 (221)

Peptidoglycan inhibits beigeing of adipose tissue

Acta Pharmaceutica Sinica B, 2022
Hong Chen, Lijun Sun, Lu Feng, Michael Mulholland, Weizhen Zhang, Yue Yin   +5 more
openaire   +3 more sources

Diffuse optical spectroscopy and imaging to detect and quantify adipose tissue browning [PDF]

, 2017
Adipose (fat) tissue is a complex metabolic organ that is highly active and essential. In contrast to white adipose tissue (WAT), brown adipose tissue (BAT) is deemed metabolically beneficial because of its ability to burn calories through heat ...
Balasundaram, G., Dinish, U. S., Olivio, M., Ong, Wee Kiat, Sriram, S., Sugii, S., Wong, C. L.   +6 more
core   +1 more source

Fighting obesity by targeting factors regulating beige adipocytes. [PDF]

, 2018
Purpose of reviewThe current review provides an update on secreted factors and mechanisms that promote a thermogenic program in beige adipocytes, and their potential roles as therapeutic targets to fight obesity.Recent findingsWe outline recent studies ...
Koliwad, Suneil K, McQueen, Allison E, Wang, Jen-Chywan   +2 more
core   +1 more source

Ontogeny and thermogenic role for sternal fat in female sheep [PDF]

, 2017
Brown adipose tissue acting through a unique uncoupling protein (UCP1) has a critical role in preventing hypothermia in new-born sheep but is then considered to rapidly disappear during postnatal life.
Albrecht, Alexander, Alexander, Atit, Bal, Barquissau, Basse, Belinda A. Henry, Bispham, Blessing, Blondin, Bloor, Cantile, Cao, Christian, Christodoulides, Clapham, Clarke, Clarke, Clarke, de Jong, Ellis, Elsen, Forner, Gburcik, Harms, Helen Budge, Henry, Henry, Henry, Henry, Horvath, Hotta, Hunt, Iain J. Clarke, John-Paul Fuller-Jackson, Kiskinis, Kooijman, Kurose, Lean, Lee, Lee, Loomis, Macotela, Mark Birtwistle, Mark Pope, Michael E. Symonds, Moldes, Møller, Nedergaard, Nedergaard, Nygaard, Ojha, Ootsuka, Petrovic, Pope, Rachael Loughnan, Ramayo-Caldas, Reham Alagal, Rosell, Rowland, Sacks, Sanchez-Gurmaches, Sanchez-Gurmaches, Scheele, Scotney, Seale, Sechen, Shan, Shinoda, Symonds, Symonds, Symonds, Symonds, Symonds, Symonds, Symonds, Timmons, van Marken Lichtenbelt, Vergnes, Virtanen, Viv Perry, Wellik, Xue, Yamamoto   +84 more
core   +2 more sources

Extracellular vesicles from adipose tissue - a potential role in obesity and type 2 diabetes? [PDF]

, 2017
Adipose tissue plays a key role in the development of insulin resistance and its pathological sequelae such as type 2 diabetes and non-alcoholic fatty liver disease. Dysfunction in the adipose tissue response to storing excess fatty acids as triglyceride
Freeman, Dilys J., Gao, Xuan, Salomon, Carlos   +2 more
core   +1 more source

Optical imaging for brown or beige adipose tissue

VIEW
AbstractCurrently, one in three adults worldwide may be obese or overweight. Obesity is characterized by an excess of energy‐storing white fat. An ingenious and sought‐after strategy against obesity is to activate energy‐consuming beige fat, which is converted from white fat or brown fat.
Jiamin Liu, Linjie Ni, Minmin Peng, Yiying Liang, Chan Lu, Hanying Zheng, Zicheng Huang, Jinde Zhang, Ronghe Chen   +8 more
openaire   +2 more sources

FTO Obesity Variant Circuitry and Adipocyte Browning in Humans [PDF]

, 2015
Background Genomewide association studies can be used to identify disease-relevant genomic regions, but interpretation of the data is challenging. The FTO region harbors the strongest genetic association with obesity, yet the mechanistic basis of this ...
Abdennur, Nezar Alexander, Beaudry, Jacqueline L., Claussnitzer, Melina, Dankel, Simon N., Drucker, Daniel J., Glunk, Viktoria, Haugen, Christine, Hauner, Hans, Hsu, Yi-Hsiang, Hui, Chi-Chung, Kellis, Manolis, Kim, Kyoung-Han, Liu, Jannel, Mellgren, Gunnar, Meuleman, Wouter, Puviindran, Vijitha, Quon, Gerald, Sousa, Isabel S., Svensson, Per-Arne   +18 more
core   +1 more source

An epigenome atlas of mouse adipocytes

Molecular Metabolism
Objective: Epigenetic modifications including histone post translational modifications can influence gene expression in adipocytes, potentially contributing to metabolic dysfunctions, obesity, and insulin resistance.
Laura C. Hinte, Adhideb Ghosh, Daniel Castellano-Castillo, Christian Wolfrum, Ferdinand von Meyenn   +4 more
doaj   +1 more source

Activation of estrogen receptor alpha induces beiging of adipocytes

Molecular Metabolism, 2018
Objectives: Brown adipose tissue (BAT) and BAT-like adipose tissues, referred to as ‘beige’ adipose tissues uncouple respiration from ATP synthesis via uncoupling protein one (UCP-1).
Roberta S. Santos, Aaron P. Frank, Luciana A. Fátima, Biff F. Palmer, Orhan K. Öz, Deborah J. Clegg   +5 more
doaj   +1 more source

Autophagy in Myf5+ progenitors regulates energy and glucose homeostasis through control of brown fat and skeletal muscle development [PDF]

, 2013
Macroautophagy (MA) regulates cellular quality control and energy balance. For example, loss of MA in aP2-positive adipocytes converts white adipose tissue (WAT) into brown adipose tissue (BAT)-like, enhancing BAT function and thereby insulin sensitivity.
Claire C Bastie, Diana Athonvarangkul, Gary J Schwartz, Haihong Zong, Jeffrey E Pessin, Luisa Coletto, Nuria Martinez‐Lopez, Rajat Singh, Srabani Sahu, Tallquist MD   +9 more
core   +2 more sources