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Adoptive T Cell Immunotherapy for Cancer [PDF]

open access: yesRambam Maimonides Medical Journal, 2015
Harnessing the immune system to recognize and destroy tumor cells has been the central goal of anti-cancer immunotherapy. In recent years, there has been an increased interest in optimizing this technology in order to make it a clinically feasible ...
Karlo Perica   +3 more
doaj   +4 more sources

Adoptive Immunotherapy in Chimeras with Donor Lymphocytes [PDF]

open access: yesActa Haematologica, 2003
Allogeneic stem cell transplantation has a well-defined indication in the treatment of hematological malignancies. The beneficial immune effect of allogeneic marrow transplantation has long been known, but only recently have methods been developed to ...
Chen, Xiao   +8 more
core   +6 more sources

Adoptive immunotherapy for cytomegalovirus infection [PDF]

open access: yesJournal of Applied Sciences and Environmental Management, 2005
We reported a case with interstitial pneumonia associated with cytomegalovirus (CMV) infection in whom clinical improvement was observed after the treatment with primary adoptive immunotherapy.
M D Kei Numazaki
doaj   +3 more sources

Adoptive immunotherapy against ovarian cancer [PDF]

open access: yesJournal of Ovarian Research, 2016
The standard front-line therapy for epithelial ovarian cancer (EOC) is combination of debulking surgery and platinum-based chemotherapy. Nevertheless, the majority of patients experience disease recurrence.
G. Mittica   +6 more
semanticscholar   +4 more sources

ADOPTIVE IMMUNOTHERAPY IN CANINE CHIMERAS1

open access: bronzeTransplantation, 1997
Chimerism and tolerance after bone marrow transplantation provide excellent conditions for adoptive immunotherapy with T cells of the marrow donor. We studied adoptive immunotherapy in dog leukocyte antigen-identical canine littermate chimeras. Mixed chimeras were produced by conditioning treatment with total body irradiation of a dose of 10 Gy, a ...
Hans‐Jochem Kolb   +5 more
openalex   +4 more sources

Cancer-cell stiffening via cholesterol depletion enhances adoptive T-cell immunotherapy

open access: yesNature Biomedical Engineering, 2021
Malignant transformation and tumour progression are associated with cancer-cell softening. Yet how the biomechanics of cancer cells affects T-cell-mediated cytotoxicity and thus the outcomes of adoptive T-cell immunotherapies is unknown.
Kewen Lei   +15 more
semanticscholar   +1 more source

Tracking adoptive T cell immunotherapy using magnetic particle imaging

open access: yesNanotheranostics, 2021
Adoptive cellular therapy (ACT) is a potent strategy to boost the immune response against cancer. ACT is effective against blood cancers but faces challenges in treating solid tumors.
Angelie Rivera-Rodriguez   +6 more
semanticscholar   +1 more source

A novel and effective cancer immunotherapy mouse model using antigen-specific B cells selected in vitro. [PDF]

open access: yesPLoS ONE, 2014
Immunotherapies such as adoptive transfer of T cells or natural killer cells, or monoclonal antibody (MoAb) treatment have recently been recognized as effective means to treat cancer patients.
Tatsuya Moutai   +3 more
doaj   +1 more source

Stem-like CD8 T cells mediate response of adoptive cell immunotherapy against human cancer

open access: yesScience, 2020
Stem-like T cells mediate response Adoptive cell transfer (ACT) is a type of immunotherapy that uses a patient's own T lymphocytes to recognize and attack cancer.
S. Krishna   +21 more
semanticscholar   +1 more source

Adoptive immunotherapy for posttransplantation viral infections [PDF]

open access: hybridBiology of Blood and Marrow Transplantation, 2004
Viral diseases are a major cause of morbidity and mortality after hemopoietic stem cell transplantation. Because viral complications in these patients are clearly associated with the lack of recovery of virus-specific cellular immune responses, reconstitution of the host with in vitro expanded cytotoxic T lymphocytes is a potential approach to prevent ...
Catherine M. Bollard   +4 more
openalex   +4 more sources

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