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Adoptive T Cell Immunotherapy for Cancer [PDF]
Rambam Maimonides Medical Journal, 2015 Harnessing the immune system to recognize and destroy tumor cells has been the central goal of anti-cancer immunotherapy. In recent years, there has been an increased interest in optimizing this technology in order to make it a clinically feasible ...
Karlo Perica +3 more
doaj +4 more sources
Adoptive Immunotherapy in Chimeras with Donor Lymphocytes [PDF]
Acta Haematologica, 2003 Allogeneic stem cell transplantation has a well-defined indication in the treatment of hematological malignancies. The beneficial immune effect of allogeneic marrow transplantation has long been known, but only recently have methods been developed to ...
Chen, Xiao +8 more
core +6 more sources
Adoptive immunotherapy for cytomegalovirus infection [PDF]
Journal of Applied Sciences and Environmental Management, 2005 We reported a case with interstitial pneumonia associated with cytomegalovirus (CMV) infection in whom clinical improvement was observed after the treatment with primary adoptive immunotherapy.
M D Kei Numazaki
doaj +3 more sources
Adoptive immunotherapy against ovarian cancer [PDF]
Journal of Ovarian Research, 2016 The standard front-line therapy for epithelial ovarian cancer (EOC) is combination of debulking surgery and platinum-based chemotherapy. Nevertheless, the majority of patients experience disease recurrence.
G. Mittica +6 more
semanticscholar +4 more sources
ADOPTIVE IMMUNOTHERAPY IN CANINE CHIMERAS1
Transplantation, 1997 Chimerism and tolerance after bone marrow transplantation provide excellent conditions for adoptive immunotherapy with T cells of the marrow donor. We studied adoptive immunotherapy in dog leukocyte antigen-identical canine littermate chimeras. Mixed chimeras were produced by conditioning treatment with total body irradiation of a dose of 10 Gy, a ...
Hans‐Jochem Kolb +5 more
openalex +4 more sources
Cancer-cell stiffening via cholesterol depletion enhances adoptive T-cell immunotherapy
Nature Biomedical Engineering, 2021 Malignant transformation and tumour progression are associated with cancer-cell softening. Yet how the biomechanics of cancer cells affects T-cell-mediated cytotoxicity and thus the outcomes of adoptive T-cell immunotherapies is unknown.
Kewen Lei +15 more
semanticscholar +1 more source
Tracking adoptive T cell immunotherapy using magnetic particle imaging
Nanotheranostics, 2021 Adoptive cellular therapy (ACT) is a potent strategy to boost the immune response against cancer. ACT is effective against blood cancers but faces challenges in treating solid tumors.
Angelie Rivera-Rodriguez +6 more
semanticscholar +1 more source
A novel and effective cancer immunotherapy mouse model using antigen-specific B cells selected in vitro. [PDF]
PLoS ONE, 2014 Immunotherapies such as adoptive transfer of T cells or natural killer cells, or monoclonal antibody (MoAb) treatment have recently been recognized as effective means to treat cancer patients.
Tatsuya Moutai +3 more
doaj +1 more source
Stem-like CD8 T cells mediate response of adoptive cell immunotherapy against human cancer
Science, 2020 Stem-like T cells mediate response Adoptive cell transfer (ACT) is a type of immunotherapy that uses a patient's own T lymphocytes to recognize and attack cancer.
S. Krishna +21 more
semanticscholar +1 more source
Adoptive immunotherapy for posttransplantation viral infections [PDF]
Biology of Blood and Marrow Transplantation, 2004 Viral diseases are a major cause of morbidity and mortality after hemopoietic stem cell transplantation. Because viral complications in these patients are clearly associated with the lack of recovery of virus-specific cellular immune responses, reconstitution of the host with in vitro expanded cytotoxic T lymphocytes is a potential approach to prevent ...
Catherine M. Bollard +4 more
openalex +4 more sources