Results 11 to 20 of about 61,359 (235)
eLife, 2017 The modification of serines by molecules of ADP-ribose plays an important role in signaling that the DNA in a cell has been damaged and needs to be repaired.
Giuliana Katharina Moeller +1 more
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ADP-ribosylation of arginine [PDF]
Amino Acids, 2010 Arginine adenosine-5'-diphosphoribosylation (ADP-ribosylation) is an enzyme-catalyzed, potentially reversible posttranslational modification, in which the ADP-ribose moiety is transferred from NAD(+) to the guanidino moiety of arginine. At 540 Da, ADP-ribose has the size of approximately five amino acid residues.
Sabrina Laing +3 more
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ADP-Ribosylation in Antiviral Innate Immune Response
Pathogens, 2023 Adenosine diphosphate (ADP)-ribosylation is a reversible post-translational modification catalyzed by ADP-ribosyltransferases (ARTs). ARTs transfer one or more ADP-ribose from nicotinamide adenine dinucleotide (NAD+) to the target substrate and release ...
Qian Du, Ying Miao, Wei He, Hui Zheng
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Functional roles of ADP-ribosylation writers, readers and erasers
Frontiers in Cell and Developmental Biology, 2022 ADP-ribosylation is a reversible post-translational modification (PTM) tightly regulated by the dynamic interplay between its writers, readers and erasers.
Ping Li +4 more
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Pathogens, 2023 Poly ADP-ribose polymerases (PARPs) catalyze ADP-ribosylation, a subclass of post-translational modification (PTM). Mono-ADP-ribose (MAR) moieties bind to target molecules such as proteins and nucleic acids, and are added as part of the process which ...
Ramesh Kumar +3 more
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ADP-ribosylation of DNA and RNA
DNA Repair, 2021 ADP-ribosylation is a chemical modification of macromolecules found across all domains of life and known to regulate a variety of cellular processes. Notably, it has a well-established role in the DNA damage response. While it was historically known as a post-translational modification of proteins, recent studies have shown that nucleic acids can also ...
Groslambert, Joséphine +2 more
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Uncovering the Invisible: Mono-ADP-ribosylation Moved into the Spotlight
Cells, 2021 Adenosine diphosphate (ADP)-ribosylation is a nicotinamide adenine dinucleotide (NAD+)-dependent post-translational modification that is found on proteins as well as on nucleic acids.
Ann-Katrin Hopp, Michael O. Hottiger
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Temporal and Site-Specific ADP-Ribosylation Dynamics upon Different Genotoxic Stresses
Cells, 2021 The DNA damage response revolves around transmission of information via post-translational modifications, including reversible protein ADP-ribosylation.
Sara C. Buch-Larsen +3 more
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Selective monitoring of the protein-free ADP-ribose released by ADP-ribosylation reversal enzymes.
PLoS ONE, 2021 ADP-ribosylation is a key post-translational modification that regulates a wide variety of cellular stress responses. The ADP-ribosylation cycle is maintained by writers and erasers.
Samuel Kasson +2 more
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iScience, 2021 Summary: While protein ADP-ribosylation was reported to regulate differentiation and dedifferentiation, it has so far not been studied during transdifferentiation. Here, we found that MyoD-induced transdifferentiation of fibroblasts to myoblasts promotes
Lavinia Bisceglie +11 more
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