Results 41 to 50 of about 1,348 (124)

Progress On Sensorineural Hearing Loss: Mechanisms and Therapies

Sensory Neuroscience, Volume 2, Issue 2, June 2026.
ABSTRACT Hearing loss is the most common disabling disease among humans, which adversely affects human health. Sensorineural hearing loss (SNHL) accounting for approximately 63% of all hearing loss cases. SNHL may be classified into age‐related hearing loss (ARHL), drug‐induced hearing loss (DIHL), noise‐induced hearing loss (NIHL), and sudden ...
Yuan Zhang, Shen Li, Yangfan Zhou, Duopin Li, Junru Ding, Ruifeng Qiao, Yutian Chen, Fanglei Ye, Le Wang, Peipei Li   +9 more
wiley   +1 more source

Association between Vitamin D Level and Sensorineural Hearing Loss in Adults: Systematic Review and Meta‐Analysis

Food Science &Nutrition, Volume 14, Issue 4, April 2026.
This graphical abstract illustrates the methodology and key findings of our systematic review and meta‐analysis. We comprehensively searched 4 databases, including 5 observational studies with a total of 1936 participants. The study aimed to compare serum vitamin D levels between adults with sensorineural hearing loss (SNHL) and healthy controls.
Ahd Mortada Awad Mohmed, Tasnim Omer Mohamed Elawad, Abrar Abd Elmohaimin Ali Mohammed, Tanzeel MohamedSalih, Mohamed H. Elbadawi, Yousef Mohamed Ahmed Alslawy   +5 more
wiley   +1 more source

Inhibitory control and value-directed strategic attention in persons with mild age-related hearing loss

Aging and Health Research, 2022
Background: Growing evidence suggests changes in cognitive control in persons with age-related hearing loss (ARHL); however, the nature of these alterations especially in those with mild ARHL needs further investigation.
Shraddha A. Shende, Elizabeth A. Lydon, Fatima T. Husain, Raksha A. Mudar   +3 more
doaj   +1 more source

Brimonidine Therapy for Protection From Noise‐Induced Hearing Loss

Aging Cell, Volume 25, Issue 4, April 2026.
In this study, we demonstrate that brimonidine protects against noise‐induced hearing loss in young mice by suppressing glutamate synthesis and vesicle transport, thereby reducing excitotoxicity and preserving synaptic integrity. Such early intervention may prevent age‐related hearing loss, highlighting brimonidine's potential as a therapeutic agent ...
Jing Cai, Na Zhang, Yongdong Song, Chengfang Chen, Ligang Kong, Yu Ai, Yu Jin, Qian Gao, Daogong Zhang, Lei Xu, Haibo Wang   +10 more
wiley   +1 more source

The Impacts of Age-Related Peripheral Hearing Loss, Central Auditory Processing, and Cognition on Quality of Life in Older Adults: A Scoping Review

Journal of Ageing and Longevity
This scoping review aims to synthesize peer-reviewed literature exploring quality of life (QoL) for individuals with age-related hearing loss (ARHL), age-related central auditory processing (ARCAP) deficits, and age-related cognitive decline.
Samantha E. Vasquez, Anna J. Bierma, Brian M. Kreisman   +2 more
doaj   +1 more source

Endometrial Stromal Cell Senescence: A Non‐Negligible Factor in Recurrent Pregnancy Loss

iMetaMed, Volume 2, Issue 1, March 2026.
As populations age, links between female reproductive aging and infertility are increasingly evident. Cellular senescence, characterized by near‐irreversible cell‐cycle arrest and accumulation of damage, can impair tissue function. In the endometrium, aberrant senescence of endometrial stromal cells (EnSCs) may compromise receptivity, hinder embryo ...
Shuang Wu, Cenlan Bu, Qinzheng Xu, Xi Cheng, Junrong Zhang, Jinling Chen, Yun‐Zhao Xu   +6 more
wiley   +1 more source

Evaluation of retinal nerve fiber layer thickness in patients with age-related hearing loss

Van Tıp Dergisi, 2019
INTRODUCTION: To perform retinal nerve fibre layer (RNFL) thickness in patients with age-related hearing loss (ARHL) using Optical coherence tomography (OCT).
Hüseyin Fındık, Metin Çeliker
doaj   +1 more source

Pathogenesis of Age‐Related Hearing Loss and Therapeutic Strategies

Sensory Neuroscience, Volume 2, Issue 1, March 2026.
ABSTRACT Age‐related hearing loss (ARHL) is a degenerative disorder of the auditory system, characterized by bilateral symmetrical sensorineural hearing loss that occurs with aging. As a highly prevalent age‐related condition worldwide, ARHL significantly impairs both the quality of life and mental health of the elderly.
Yu Xiao, Jiaxin Liu, Xiaohan Zhang, Miao Chang, Cheng Cheng, Yunhao Wu, Xiaolong Fu   +6 more
wiley   +1 more source

Hearing analysis in heterozygous and homozygous klotho gene deficient mice

Journal of Otology, 2018
Objective: To understand the crucial role of the klotho gene in hearing development in mouse models. Methods: PCR was used to identify CBA mice with different genotypes, i.e. WT, heterozygous (klotho +/−) or homozygous (klotho −/−).
Na Yuan, Shiwei Qiu, Qian Wang, Wei Zhuang, Guoping Li, Tiantian Sun, Shiming Yang, Yuehua Qiao, Xi Shi   +8 more
doaj   +1 more source

Hearing Loss: From Basic to Clinical Science

Advanced Science, Volume 13, Issue 7, 3 February 2026.
Abstract Hearing loss (HL) affects over 1.5 billion people globally, with genetic factors accounting for ≈50% of congenital cases. Therefore, HL has become a global health issue, driving extensive research from basic science to clinical applications. This Special Collection includes a total of 31 papers, among which 9 are review papers, 21 are research
Renjie Chai, Hai Huang, Jing Zou
wiley   +1 more source