Results 21 to 30 of about 511,853 (298)
Clinical Epigenetics, 2023 Background Epigenetic age acceleration (EAA) and epigenetic gestational age acceleration (EGAA) are biomarkers of physiological development and may be affected by the perinatal environment.
Anne K. Bozack +6 more
doaj +1 more source
Ground reaction force estimates from ActiGraph GT3X+ hip accelerations. [PDF]
, 2014 Simple methods to quantify ground reaction forces (GRFs) outside a laboratory setting are needed to understand daily loading sustained by the body. Here, we present methods to estimate peak vertical GRF (pGRFvert) and peak braking GRF (pGRFbrake) in ...
Collins, Kelsey H +2 more
core +2 more sources
DNA Methylomes and Epigenetic Age Acceleration Associations with Poor Metabolic Control in T1D
Biomedicines, 2020 Type 1 diabetes (T1D) is an autoimmune disease that leads to insulin deficiency and hyperglycemia. Little is known about how this metabolic dysfunction, which substantially alters the internal environment, forces cells to adapt through epigenetic ...
Raúl F Pérez +6 more
doaj +1 more source
Epigenetic Age Acceleration and Hearing: Observations From the Baltimore Longitudinal Study of Aging
Frontiers in Aging Neuroscience, 2021 Objectives: Age-related hearing loss (ARHL) is highly prevalent among older adults, but the potential mechanisms and predictive markers for ARHL are lacking.
Pei-Lun Kuo +4 more
doaj +1 more source
Associations Between Blood Pressure and Accelerated DNA Methylation Aging
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022 Background Individuals of the same chronological age may exhibit diverse susceptibilities to death. However, few studies have investigated the associations between blood pressure and the accelerated aging.
Lili Xiao +7 more
doaj +1 more source
Obesity accelerates thymic aging
Blood, 2009 Abstract As the expanding obese population grows older, their successful immunologic aging will be critical to enhancing the health span. Obesity increases risk of infections and cancer, suggesting adverse effects on immune surveillance.
Hyunwon, Yang +6 more
openaire +3 more sources
Failure of immunosurveillance accelerates aging [PDF]
OncoImmunology, 2019 Immunosurveillance is generally conceived as a mechanism through which the immune system detects and eliminates (pre-)malignant cells, thus reducing the risk of developing cancer. A recent paper by Ovadya et al. demonstrates that knockout of the gene coding for perforin-1 causes accelerated accumulation of senescent cells in multiple mouse organs ...
Maria Perez-Lanzon +2 more
openaire +4 more sources
Bulk Viscosity, Decaying Dark Matter, and the Cosmic Acceleration [PDF]
, 2006 We discuss a cosmology in which cold dark-matter particles decay into relativistic particles. We argue that such decays could lead naturally to a bulk viscosity in the cosmic fluid.
A. G. Doroshkevich +7 more
core +3 more sources
The Journal of nutrition, health and aging, 2023 Abstract Obesity in the older population has increased in prevalence and incidence over the last several decades and has been associated with a decline in physical function, quality of life, and increased risk of complications from cardiometabolic diseases. Several interrelated hallmarks of aging have been proposed.
openaire +1 more source
Subfertility reflects accelerated ovarian ageing [PDF]
Human Reproduction, 2003 The aim of the study was to explore the extent to which accelerated ovarian ageing may lead to subfertility early in reproductive life and eventually cause early menopause.The population studied (n = 2393) never used oral contraceptives, hormone replacement therapy or an intrauterine device.
Kok, Helen S. +6 more
openaire +3 more sources