Results 31 to 40 of about 5,559,088 (293)
Biological Ageing Acceleration and Functional Capacities Across the Lifespan in the INSPIRE‐T Cohort
Background Biological clocks are promising tools for the evaluation of biological age deviations (i.e., positive/negative acceleration). Here, we explored the associations of biological age acceleration (BAA) assessed by Horvath's, Hannum's, PhenoAge ...
Juan Luis Sánchez‐Sánchez +9 more
doaj +1 more source
Age-Specific Acceleration of Cancer [PDF]
One of the great challenges of cancer research is to explain the epidemiological patterns of cancer incidence based on the molecular processes that lead to uncontrolled cellular proliferation. The epidemiological data demonstrate that the age-specific incidence of many cancers increases in an approximately linear way with age when plotted on a log-log ...
openaire +2 more sources
Is Schizophrenia a Syndrome of Accelerated Aging? [PDF]
Schizophrenia is associated with a number of anatomical and physiological abnormalities outside of the brain, as well as with a decrease in average life span estimated at 20% in the United States. Some studies suggest that this increased mortality is not entirely due to associated causes such as suicide and the use of psychotropic medications.
Brian, Kirkpatrick +4 more
openaire +2 more sources
Acceleration: An interpretive study of gifted students within a primary school setting [PDF]
The purpose of this study was to investigate the experiences of gifted Primary School aged students who had been year level accelerated in Western Australia.
Gamble, Christina
core
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
ON RADIATION-INDUCED AGING: ACCELERATED OR PREMATURE AGING
Abstract The concept of radiation-induced aging is revisited from the viewpoint of a mathematical model. The effect of radiation on carcinogenesis is treated based on the Armitage–Doll multi-stage theory. The formula obtained for cancer incidence rate indicates that radiation dose can be explained in terms of time.
Takahiro Wada +2 more
openaire +2 more sources
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin +2 more
wiley +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Additional acceleration of solar-wind particles in current sheets of the heliosphere [PDF]
Particles of fast solar wind in the vicinity of the heliospheric current sheet (HCS) or in a front of interplanetary coronal mass ejections (ICMEs) often reveal very peculiar energy or velocity profiles, density distributions with double or triple peaks,
V. Zharkova +4 more
core +2 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source

