Results 71 to 80 of about 614,051 (372)
Establishment and Selection of Indicator Materials for Cervi Parvum Cornu Pharmacopuncture [PDF]
Journal of Acupuncture Research, 2017 Background Recently, Cervi Parvum Cornu pharmacopuncture has been widely used. But no studies on the indicator materials for Cervi Parvum Cornu pharmacopuncture have been conducted.
Kyu-Jin Yang +10 more
doaj +1 more source
Approximating nonequilibrium processes using a collection of surrogate diffusion models [PDF]
J. Chem. Phys. (2008) no. 145103 vol. 128, 2008 The surrogate process approximation (SPA) is applied to model the nonequilibrium dynamics of a reaction coordinate (RC) associated with the unfolding and refolding processes of a deca-alanine peptide at 300 K. The RC dynamics, which correspond to the evolution of the end-to-end distance of the polypeptide, are produced by steered molecular dynamics ...
arxiv +1 more source
The Journal of Antibiotics, 1987 The biosynthesis from L-alanine of D-alanyl-D-alanine, required for the peptidoglycan layer of the cell wall of many bacterial species, is catalyzed by two enzymes in series, alanine racemase and D-alanine: D-alanine ligase. A simple in vitro method, called the combined assay, for simultaneously testing for effectors of either or both enzymes in a ...
Howard M. Katzen +2 more
openaire +4 more sources
Inhibitors of alanine racemase enzyme: a review
Journal of Enzyme Inhibition and Medicinal Chemistry, 2015 Alanine racemase is a fold type III PLP-dependent amino acid racemase enzyme catalysing the conversion of l-alanine to d-alanine utilised by bacterial cell wall for peptidoglycan synthesis. As there are no known homologs in humans, it is considered as an
M. Azam, U. Jayaram
semanticscholar +1 more source
FEBS Open Bio, EarlyView.T2DM is characterized by peripheral blood insulin resistance and progressive pancreatic β‐cell dysfunction. Here, we showed that AQP7, the only aquaglyceroporin protein, regulates autophagy and apoptosis in pancreatic β‐cells. We propose the existence of a positive feedback loop between MAPK signaling and AQP7 that regulates autophagy and apoptosis in ...
Maoqi Wang +5 more
wiley +1 more source
The content of non-essential amino acids in the grains of winter and spring varieties of oats (Avena sativa L.) under the conditions of Central Southern Bulgaria [PDF]
Agroznanje, 2013 The purpose of this survey is to study the content of non-essential amino acids in four winter (Dunav 1, Ruse 8, Resor 1, Line M-K) and five spring (Obraztsov chiflik 4, Mina, HiFi, Novosadski golozarnest and Prista 2) cultivars of oats grown in Central ...
Georgieva T., Zorovski P.
doaj +1 more source
FEBS Open Bio, EarlyView.Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui +15 more
wiley +1 more source
Alpha helix-coil phase transition: analysis of ab initio theory predictions [PDF]
, 2007 In the present paper we present results of calculations obtained with the use of the theoretical method described in our preceding paper [1] and perform detail analysis of alpha helix-random coil transition in alanine polypeptides of different length.
arxiv +1 more source
Transferring Chemical and Energetic Knowledge Between Molecular Systems with Machine Learning [PDF]
arXiv, 2022 Predicting structural and energetic properties of a molecular system is one of the fundamental tasks in molecular simulations, and it has use cases in chemistry, biology, and medicine. In the past decade, the advent of machine learning algorithms has impacted on molecular simulations for various tasks, including property prediction of atomistic systems.
arxiv
Alanine Aminotransferase-Old Biomarker and New Concept: A Review
International Journal of Medical Sciences, 2014 Measurement of serum alanine aminotransferase (ALT) is a common, readily available, and inexpensive laboratory assay in clinical practice. ALT activity is not only measured to detect liver disease, but also to monitor overall health.
Zhengtao Liu, S. Que, Jing Xu, T. Peng
semanticscholar +1 more source