Results 111 to 120 of about 13,748 (218)

High Mobility Group Box Protein-1 in Wound Repair

Cells, 2012
High-mobility group box 1 protein (HMGB1), a member of highly conserved non-histone DNA binding protein family, has been studied as transcription factor and growth factor.
Mauro Patrone, Marco Pedrazzi, Simona Martinotti, Elia Ranzato   +3 more
doaj   +1 more source

Mouse models of preterm birth: Suggested assessment and reporting guidelines [PDF]

, 2018
Preterm birth affects approximately 1 out of every 10 births in the United States, leading to high rates of mortality and long-term negative health consequences.
England, Sarah K, Fay, Justin C, Herington, Jennifer L, Herzog, Erik D, Jungheim, Emily S, Mahendroo, Mala, Martin-Fairey, Carmel, McCarthy, Ronald, Plosa, Erin J, Reese, Jeff, Shelton, Elaine L, Sojka, Dorothy K, Stout, Molly J   +12 more
core   +2 more sources

Plasma Elastase Screening in Hematological Disease Reveals Its Potential as a Diagnostic and Prognostic Biomarker in Hematological Malignancies

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction Neutrophil‐extracellular traps are net‐like material released by triggered neutrophils and composed of decondensed chromatin linked to nuclear proteins. Elastase, one of the fourth most represented neutrophil‐specific serine proteases stored in azurophil granules of naïve neutrophils, exerts various actions, including degradation ...
Pasqualina Scala, Anna Maria Della Corte, Angela Bertolini, Marisa Gorrese, Francesca Picone, Bianca Serio, Danilo De Novellis, Laura Mettivier, Luca Pezzullo, Maria Carmen Martorelli, Denise Morini, Matteo D'Addona, Bianca Cuffa, Carmine Selleri, Valentina Giudice   +14 more
wiley   +1 more source

Association Between Helicobacter pylori cagA, babA2 Virulence Factors and Gastric Mucosal Interleukin-33 mRNA Expression and Clinical Outcomes in Dyspeptic Patients. [PDF]

, 2015
Helicobacter pylori (H. pylori) infection has been reported in more than half of the world human population. It is associated with gastric inflammation and noticeable infiltration of the immune cells to the stomach mucosa by several cytokines secretion ...
Bagheri, Nader., Bahreini, Rasoul., Reiisi, Somayeh., Salimzadeh, Loghman., Shahi, Heshmat., shirzad, Hedayatollah.   +5 more
core   +3 more sources

The Outcome of Intracellular Selenomonas sputigena and its Impact on Gingival Keratinocytes

Molecular Oral Microbiology, EarlyView.
ABSTRACT Selenomonas sputigena is an understudied oral pathobiont associated with periodontitis and dental caries. We recently demonstrated that S. sputigena binds to gingival epithelial cells (GECs), where afterwards the bacterium causes robust in vitro pro‐inflammatory cytokine production and migration of monocytes and neutrophils.
Colin G. Hawkes, Travis J. Chiarelli, Doaa N. Abdallah, Grayson Way, Huiping Zhou, Jason A. Carlyon, Daniel P. Miller   +6 more
wiley   +1 more source

RAGE Signaling in Skeletal Biology [PDF]

, 2019
PURPOSE OF REVIEW: The receptor for advanced glycation end products (RAGE) and several of its ligands have been implicated in the onset and progression of pathologies associated with aging, chronic inflammation, and cellular stress. In particular, the
Davis, Hannah M., Essex, Alyson L., Plotkin, Lilian I.   +2 more
core   +2 more sources

Evaluation of the Cutaneous Immunological Milieu Before and After Treatment With Meglumine Antimoniate in Dogs Naturally Affected by Leishmaniosis due to Leishmania infantum

Veterinary Dermatology, EarlyView.
Background: Canine leishmaniosis (CanL) is a zoonotic disease of variable severity. The typical immune response is driven by an exaggerated humoral immune response. Protective immunity is mediated by pro‐inflammatory cytokines that enhance macrophage leishmanicidal activity. Objective: To evaluate the cutaneous and the systemic immune responses as well
M. Platenik, A. Di Loria, L. Archer, M. Saridomichelakis, A. S. Benvenuto, D. Santoro   +5 more
wiley   +1 more source

Enhanced Innate Immunity Mediated by IL-36α in Atopic Dermatitis and Differences in Cytokine Profiles of Lymphocytes in the Skin and Draining Lymph Nodes

Biomolecules
(1) Background: The IL-36 cytokines have been identified as key contributors to pustular psoriasis, and their inhibitor is already in clinical use. However, few studies have explored them in atopic dermatitis.
Ayaka Ichikawa, Mai Nishimura, Masako Ichishi, Yasutomo Imai, Yoshiaki Matsushima, Yoichiro Iwakura, Masatoshi Watanabe, Kiyofumi Yamanishi, Keiichi Yamanaka   +8 more
doaj   +1 more source

Macrophage inducible C-type lectin as a multifunctional player in immunity [PDF]

, 2017
The macrophage-inducible C-type lectin (Mincle) is an innate immune receptor on myeloid cells sensing diverse entities including pathogens and damaged cells. Mincle was first described as a receptor for the mycobacterial cell wall glycolipid, trehalose-6,
Axelrod, Beamer, Behler, Behler, Behler-Janbeck, Brown, Dambuza, Decout, Devi, Drickamer, Drummond, Ebid, Feinberg, Feinberg, Feng, Flornes, Furukawa, Graham, Greco, Greco, Haraguchi, Hardison, Hattori, Heitmann, Huber, Hupfer, Iborra, Igarashi, Indrigo, Ishikawa, Ishikawa, Jacobsen, Jegouzo, Kang, Karsten, Kawata, Kerrigan, Kerscher, Kingeter, Kiyotake, Kodar, Korsholm, Kostarnoy, Kottom, Lang, Lang, Lang, Lee, Lee, Lee, Levitz, Lobato-Pascual, Maglione, Matsumoto, Matsunaga, Miyake, Miyake, Nagata, Ostrop, Ostrop, Patin, Patin, Patin, Perley, Pitt, Rabes, Richardson, Richardson, Rivera, Roperto, Schick, Schoenen, Schoenen, Seifert, Shah, Sharma, Smith, Strasser, Suzuki, Sweet, Tima, Torrelles, Turner, Weiss, Wells, Wevers, Wilson, Wuthrich, Yamasaki, Yamasaki, Zahringer, Zhang, Zhang, Zhao, Zhou   +94 more
core   +2 more sources

Immune system benefits of pulmonary rehabilitation in chronic obstructive pulmonary disease

Experimental Physiology, EarlyView.
Abstract Chronic obstructive pulmonary disease (COPD) is a respiratory disease characterized by pulmonary and systemic inflammation. Inflammatory mediators show relationships with shortness of breath, exercise intolerance and health related quality of life. Pulmonary rehabilitation (PR), a comprehensive education and exercise training programme, is the
Asghar Abbasi, David Wang, William W. Stringer, Richard Casaburi, Harry B. Rossiter   +4 more
wiley   +1 more source