Results 41 to 50 of about 13,748 (218)
Wounds that heal and wounds that don't - The role of the IL-33/ST2 pathway in tissue repair and tumorigenesis [PDF]
, 2016 IL-33 is a member of the IL-1 family of cytokines. IL-33 is predominantly located within the nucleus of cells where it plays a role in gene regulation.
Brint, Elizabeth K. +3 more
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F1000Research, 2018 Schistosomiasis is a serious but neglected tropical infectious disease, afflicting more than 240 million people in 78 countries. Lack of an effective vaccine and obscuring disease mechanism could be the main hurdles to effectively control and eradicate ...
Xing He, Weiqing Pan
doaj +1 more source
Frontiers in Immunology, 2022 Calreticulin is a chaperone, normally found in the endoplasmic reticulum, but can be released by macrophages into the extracellular medium. It is also found in cerebrospinal fluid bound to amyloid beta (Aβ).
Kyle M. Reid +4 more
doaj +1 more source
Cellular networks controlling Th2 polarization in allergy and immunity [PDF]
, 2012 In contrast to the development of Th1 (type 1 T helper cells), Th17 and Treg (regulatory T cells), little is known of the mechanisms governing Th2 development, which is important for immunity to helminths and for us to understand the pathogenesis of ...
Kool, Mirjam +2 more
core +1 more source
Innate Lymphoid Cells in Helminth Infections—Obligatory or Accessory?
Frontiers in Immunology, 2019 ILCs burst onto the immunological scene with their involvement in bacterial and helminth infections. As their influence has emerged, it has become clear that they play a fundamental role in regulating barrier tissue homeostasis and the immune response ...
Stephan Löser +3 more
doaj +1 more source
Role of High-Mobility Group Box-1 in Liver Pathogenesis [PDF]
, 2019 High-mobility group box 1 (HMGB1) is a highly abundant DNA-binding protein that can relocate to the cytosol or undergo extracellular release during cellular stress or death. HMGB1 has a functional versatility depending on its cellular location.
Huda, Nazmul +3 more
core +1 more source
A Multi-marker Model for Predicting Decompensated Heart Failure in Patients with Prior Acute Myocardial Infarction [PDF]
, 2020 The aim of the study was to assess the prognostic value of determining the plasma concentration of NT-proBNP and ST2 in the patients with decompensated HF and prior acute myocardial infarction and their combination in this category of patients.Materials ...
Levandovska, K. (Khrystyna)
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Alarmins: awaiting a clinical response [PDF]
Journal of Clinical Investigation, 2012 Alarmins are endogenous molecules that are constitutively available and released upon tissue damage and activate the immune system. Current evidence indicates that uncontrolled and excessive release of alarmins contributes to the dysregulated processes seen in many inflammatory and autoimmune conditions, as well as tumorigenesis and cancer spread ...
Chan, James K +7 more
openaire +3 more sources
Medicina, 2021 Mental disorders are common in the general population; every year about 25% of the total European population is affected by a mental condition. The prevalence of psychiatric disorders might be underestimated.
Gianluca Pandolfo +6 more
doaj +1 more source
The perioperative immune response [PDF]
, 2015 PURPOSE OF REVIEW A host of immune modulators are now available in clinical practice. The perioperative period is characterized by profound alterations in host immunity, which can result in poor outcomes, which include infection, cancer recurrence and
Akira +50 more
core +1 more source