Results 111 to 120 of about 13,578 (213)
European Journal of Immunology, Volume 56, Issue 4, April 2026.Inhaled pretreatment of mouse lungs with immunomodulatory Pam2ODN results in lung epithelial cell epigenetic reprogramming that is associated with attenuation of house dust mite extract (HDM)‐induced cDC2s and moDCs expansion in the lung, causing tolerance against HDM sensitization and restricting Th2‐cell‐induced airway eosinophilic allergic ...
Mbaya Ntita +7 more
wiley +1 more source
Clinical &Experimental Allergy, Volume 55, Issue 3, Page 253-255, March 2025.
Robert Greig +4 more
wiley +1 more source
Allergic conjunctivitis: phenotype, pathophysiology, innate immune pathways, and treatment [PDF]
Exploration of Asthma & AllergyAllergic conjunctivitis (AC) is an inflammatory disorder of the ocular surface caused by allergic reactions to environmental substances. It presents with symptoms such as itching, redness of the eye, excessive tearing, and swelling/irritation in the eyes
Tanmay Singhal +4 more
doaj +1 more source
The Therapeutic Potential of Farm Dust Extracts in a Mouse Model of Eosinophilic Inflammation
Allergy, Volume 81, Issue 4, Page 1173-1192, April 2026.Farm dust extract (FDE) treatment reduces airway eosinophilia, mucus overproduction, and MHC‐II expression on DCs, limiting antigen presentation and Th2 inflammation. It increases PD‐L1 on DCs, promoting T cell deactivation. Additionally, FDE enhances Tregs and upregulates CTLA‐4, reinforcing suppression.
Rabia Ülkü Korkmaz +16 more
wiley +1 more source
Modeling and Simulation of the Effects of Cyclic Loading on Articular Cartilage Lesion Formation
, 2013 We present a model of articular cartilage lesion formation to simulate the effects of cyclic loading. This model extends and modifies the reaction-diffusion-delay model by Graham et al.
Ayati, Bruce P. +5 more
core
SP0049 Dna aggregates as alarmins [PDF]
Annals of the Rheumatic Diseases, 2017 DNA is a large polymeric molecule that displays powerful immunological activities and operates in the context of multi-component aggregates to alarm the immune system and stimulate innate immunity. Although DNA has important roles in normal host defense, DNA can serve as an autoantigen and autoimmunogen by itself or in association with other ...
openaire +1 more source
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Oliver Brandt +2 more
wiley +1 more source
Allergy, Volume 81, Issue 4, Page 1024-1038, April 2026.ABSTRACT The European Academy of Allergy and Clinical Immunology (EAACI) established a Task Force to assess the existing data on the relationship between eosinophilic esophagitis (EoE) and allergen immunotherapy (AIT). This systematic review and meta‐analysis aimed to study the incidence of confirmed EoE, developing as a side effect of AIT to food or ...
Carlo Maria Rossi +14 more
wiley +1 more source
Memory CD8+ T Cell Protection From Viral Reinfection Depends on Interleukin-33 Alarmin Signals
Frontiers in Immunology, 2019 Memory CD8+ cytotoxic T lymphocytes (CTLs) can protect against viral reinfection. However, the signals driving rapid memory CTL reactivation have remained ill-defined.
Claudia Baumann +10 more
doaj +1 more source