Results 21 to 30 of about 32,326 (184)

Genetic and Phenotypic Features of the Five Known Polyaminopathies: A Critical Narrative Review

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Polyaminopathies are a recently described family of rare genetic neurodevelopmental disorders. Polyaminopathies disrupt the biosynthesis of the primary polyamines: putrescine, spermidine, and spermine. Snyder–Robinson syndrome results from hemizygous loss‐of‐function variants in the spermine synthase (SMS) gene, resulting in decreased or ...
Elizabeth A. VanSickle   +26 more
wiley   +1 more source

Adaptive Machine Learning Framework for Optimizing the Affinity Purification of Adeno‐Associated Viral Vectors

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Adeno‐associated viral (AAV) vectors for gene therapy are becoming integral to modern medicine, providing therapeutic options for diseases once deemed incurable. Currently, viral vector purification is a critical bottleneck in the gene therapy industry, impacting product efficacy and safety as well as accessibility and cost to patients ...
Kelvin P. Idanwekhai   +9 more
wiley   +1 more source

Ucuúba Fat (Virola surinamensis) and Cellulose Nanocrystals Functionalizing Cassava (Manihot esculenta)  Starch Films

open access: yesChemFoodChem, EarlyView.
Cassava starch films were functionalized with Ucuúba fat and cellulose nanocrystals to tailor wettability, optical, mechanical, and barrier properties. Integrating Amazonian bioresources with nanotechnology enables sustainable edible coatings with tunable performance for fresh food preservation and enhanced UV protection.
Geovana Cristina Pinto Rodrigues   +4 more
wiley   +1 more source

Design and implementation of a 3D‐printed modular distillation tower for experimental teaching in chemical engineering

open access: yesThe Canadian Journal of Chemical Engineering, EarlyView.
Abstract Several authors have reported the disconnection between the skills, abilities, and attitudes of graduates from STEM careers with the current needs of the labour market. In science and engineering fields, research has found the need for interdisciplinary approaches that encourage meaningful learning.
Úrsula Manríquez‐Tolsá   +7 more
wiley   +1 more source

Optimal Dose and Safety of Intravenous Favipiravir in Hospitalized Patients With COVID‐19: A Dose‐Escalating, Randomized Controlled Phase Ib Study

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
AGILE (NCT04746183) is a Phase Ib/IIa platform, evaluating candidates to treat COVID‐19. Candidate Specific Trial 6 evaluated the safety and optimal dose of a novel intravenous formulation of favipiravir in a dose‐escalating, open‐label, randomized, controlled, Bayesian adaptive Phase Ib trial.
Tim Rowland   +48 more
wiley   +1 more source

Dual process for improved recovery of essential oil and pectin from citrus waste

open access: yesJournal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND Citrus essential oils (EO), particularly orange essential oil (OEO) and pectin, are high‐value chemical products widely used across various industries, including pharmaceuticals, food and beverages, detergents, and cosmetics. These compounds are present in the residual by‐products generated by juice production industries, and their ...
Jorge Welti‐Chanes   +3 more
wiley   +1 more source

Optical Coherence Tomography as an Emerging Technique for Identifying Pediatric Middle Ear Effusion

open access: yesThe Laryngoscope, EarlyView.
This prospective study evaluated optical coherence tomography (OCT) as a diagnostic tool for identifying middle ear effusion (MEE) in 164 pediatric patients. OCT was determined to have a sensitivity of 74% and a specificity of 93%, comparable to otoscopy and tympanometry, with moderate agreement (κ = 0.41) between clinical and non‐clinical raters.
Roger Neuberger   +7 more
wiley   +1 more source

Diseño y construcción de un prototipo de esterilización empleando radiación UV-C para alimentos industrializados

open access: yesCedamaz, 2023
Los alimentos que se comercializan en empaques pueden estar contaminados con distintos tipos de microorganismos que producen enfermedades. El desarrollo de esta investigación brinda una solución para la esterilización de alimentos industrializados ...
Jefferson Gaona-González   +5 more
doaj   +1 more source

ALIMENTOS FUNCIONAIS

open access: yesREVISE - Revista Integrativa em Inovações Tecnológicas nas Ciências da Saúde, 2020
O artigo registra as conferências do evento congresso internacional de inovação tecnológica nas ciências da saúde: a sustentabilidade das práticas integrativas a agroecologia, mais especificamente a conferência Alimentos Funcionais. A conferência apontou a qualidade de vida humana na interação entre meio ambiente e alimento nos temas: local dos ...
openaire   +2 more sources

Urbanization and food transition in the Brazilian Amazon: From wild to domesticated meat

open access: yesPeople and Nature, EarlyView.
Abstract Urbanization is expected to influence food transitions, resulting in a shift from wild foods to more domesticated foods. Concomitantly, food insecurity and urban demand for natural resources, including wildlife, are expected to increase overall, even when the per capita consumption is expected to decrease.
Willandia A. Chaves   +7 more
wiley   +1 more source

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