Results 71 to 80 of about 47,878 (245)

Exploring the Antiviral Potential of Tungsten Oxide Nanoparticles Against Herpes Simplex Virus Type 1: A Promising Alternative to Acyclovir

IET Nanobiotechnology, Volume 2026, Issue 1, 2026.
Herpes simplex virus type 1 (HSV‐1) is responsible for the majority of cold sores, herpetic keratitis‐induced blindness, profound skin lesions, and encephalitis that can be fatal. Currently, acyclovir and its derivatives are the first‐line therapy for the treatment of HSV‐1 infection.
Abdulhussain Kadhim Jwaziri, Pegah Khales, Seyed Jalal Kiani, Homayoun Yaghouti, Roghayeh Babaei, Zahra Salavatiha, Ahmad Tavakoli, Akon Higuchi   +7 more
wiley   +1 more source

Bovine alphaherpesvirus type 5 replicates more efficiently than bovine alphaherpesvirus type 1 in undifferentiated human neural cells

Virus Research, 2020
Bovine herpesvirus (BoHV) types 1 and 5 are two closely related alpha-herpesviruses of cattle with neuroinvasive potential. BoHV-5 causes non-suppurative meningoencephalitis in calve whereas encephalitis caused by BoHV-1 has been occasionally reported. As an initial step to understand the biology of both BoHV types in neural cells, undifferentiated SH ...
Rosales, Juan José, Verna, Andrea Elizabeth, Marin, Maia Solange, Pérez, Sandra   +3 more
openaire   +3 more sources

Genetic characterization of the unique short segment of phocid herpesvirus type 1 reveals close relationships among alphaherpesviruses of hosts of the order Carnivora [PDF]

, 2003
To further characterize phocid herpesvirus type 1 (PhHV-1) at the molecular level, a cluster of genes comprising the complete unique short (Us) region of PhHV-1 has been cloned and sequenced.
Harder, T.C. (Timm), Martina, B.E.E. (Byron), Osterhaus, A.D.M.E. (Albert)   +2 more
core   +1 more source

Assessing Nanopore Targeted Sequencing for the Diagnosis of Pulmonary Infections: A Comparative Multidisease Approach

Canadian Journal of Infectious Diseases and Medical Microbiology, Volume 2026, Issue 1, 2026.
Pulmonary infections remain a significant global health burden, particularly in immunocompromised individuals and patients with chronic respiratory or systemic diseases. Conventional microbiological tests (CMTs), though widely used, often have limited sensitivity and delayed results, especially in polymicrobial or atypical infections.
Ying Zhao, Guannan Ma, Tianxiao Ma, Yongshuai Miao, Heya Na, Yuhui Liu, Xiaohua Li, Arif Ansori   +7 more
wiley   +1 more source

Unique structures in a tumor herpesvirus revealed by cryo-electron tomography and microscopy. [PDF]

, 2008
Gammaherpesviruses, including the human pathogens Epstein-Barr virus and Kaposi\u27s sarcoma-associated herpesvirus, are causative agents of lymphomas and other malignancies.
Atanasov, Ivo, Bortz, Eric, Dai, Wei, Jia, Qingmei, Li, Xudong, Liu, Jun, Shah, Sanket, Sun, Ren, Taylor, Kenneth A, Zhou, Z Hong   +9 more
core   +1 more source

Towards Integrated Surveillance of Marine Brucellosis: Diagnostic and Phylogenetic Assessment of Brucella ceti in Stranded Dolphins of the Western Mediterranean Sea

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Reports of brucellosis in free‐ranging cetaceans are increasing worldwide, particularly in the Mediterranean Sea. To enhance diagnostic accuracy and epidemiological understanding of cetacean brucellosis in the Western Mediterranean Sea, we analyzed bacteriological, serological, and molecular data from 30 cetaceans belonging to three different species ...
Ignacio Vargas-Castro, Sara Andrés-Barranco, José Luis Crespo-Picazo, Laura Torre-Fuentes, Mª Ángeles Jiménez-Martínez, Marta Hernández, Manuel Arbelo, Julio Álvarez, Pilar María Muñoz, Vicente Marco-Cabedo, María Jesús de Miguel, Débora López, Marta Muñoz-Baquero, Daniel García-Párraga, José Ángel Barasona, Zongfu Wu   +15 more
wiley   +1 more source

The Requirement of Glycoprotein C for Interindividual Spread Is Functionally Conserved within the Alphaherpesvirus Genus (Mardivirus), but Not the Host (Gallid)

Viruses, 2021
Marek’s disease (MD) in chickens is caused by Gallid alphaherpesvirus 2, better known as MD herpesvirus (MDV). Current vaccines do not block interindividual spread from chicken-to-chicken, therefore, understanding MDV interindividual spread provides ...
Widaliz Vega-Rodriguez, Nagendraprabhu Ponnuraj, Maricarmen Garcia, Keith W. Jarosinski   +3 more
doaj   +1 more source

Unveiling Novel Viral Diversity, Biogeography, and Host Networks in Wildlife Through High‐Throughput Sequencing Data Mining

Advanced Science, Volume 12, Issue 46, December 11, 2025.
Analysis of 57 536 high‐throughput sequencing datasets uncovers a vast, hidden world of viruses in wildlife. The researchers reveal significant geographic and host‐specific patterns of viruses, and their surprising cross‐species transmissions, such as avian flu viruses infecting goats.
Hai Wang, Yafei Meng, Xiaoyuan Chen, Xinyuan Cui, Qian Zuo, Na Han, Xianghui Liang, Xuejuan Shen, Caiwu Li, Desheng Li, Fumin Wang, Liangping He, Rujian Chen, Xingbang Lu, Wenjie You, Aiping Wu, Rui‐Ai Chen, Wu Chen, Chan Ding, Yongyi Shen   +19 more
wiley   +1 more source

Isolation and characterization of a chimpanzee alphaherpesvirus

Journal of General Virology, 2006
Although both beta- and gammaherpesviruses indigenous to great-ape species have been isolated, to date all alphaherpesviruses isolated from apes have proven to be human viruses [herpes simplex virus types 1 (HSV1) and 2 (HSV2) or varicella-zoster virus].
Emily, Luebcke, Edward, Dubovi, Darla, Black, Kazutaka, Ohsawa, Richard, Eberle   +4 more
openaire   +2 more sources

New Paradigms for the Study of Ocular Alphaherpesvirus Infections: Insights into the Use of Non-Traditional Host Model Systems

Viruses, 2017
Ocular herpesviruses, most notably human alphaherpesvirus 1 (HSV-1), canid alphaherpesvirus 1 (CHV-1) and felid alphaherpesvirus 1 (FHV-1), infect and cause severe disease that may lead to blindness.
Matthew R. Pennington, Eric C. Ledbetter, Gerlinde R. Van de Walle   +2 more
doaj   +1 more source