Results 81 to 90 of about 47,878 (245)

The Enduring Legacy of Randall Cohrs: A Meeting of the Minds in the Rocky Mountains

Viruses, 2022
Randall Cohrs established the Colorado Alphaherpesvirus Latency Society (CALS) in 2011 [...]
Charles Grose, Joel Rovnak, Ravi Mahalingam   +2 more
doaj   +1 more source

HSV‐1 US3: A Master Mimic Hijacking Host Kinase Networks for Viral Dominance

Journal of Medical Virology, Volume 97, Issue 12, December 2025.
ABSTRACT Herpes simplex virus type 1 (HSV‐1) encodes the serine/threonine kinase US3, a central regulator of host–virus interactions that promotes viral replication, latency, and reactivation. Despite limited sequence homology to cellular kinases such as Akt or PKA, US3 phosphorylates diverse substrates to manipulate multiple pathways.
Imran Hossain, Christella J. Nelson, Ojasvi Dutta, Harikrishnan Mohan, Mehedi Hasan, Konstantin G. Kousoulas   +5 more
wiley   +1 more source

In Vivo Egress of an Alphaherpesvirus from Axons [PDF]

Journal of Virology, 2002
ABSTRACT Many alphaherpesviruses establish a latent infection in the peripheral nervous systems of their hosts. This life cycle requires the virus to move long distances in axons toward the neuron's cell body during infection and away from the cell body during reactivation.
Mark J, Tomishima, Lynn W, Enquist
openaire   +2 more sources

Histopathological and genetic characterisation of Marek's disease in Sebright chickens from Brazil

Veterinary Record Case Reports, Volume 13, Issue 4, December 2025.
Abstract Marek's disease is a lymphoproliferative condition caused by Gallid alphaherpesvirus 2 (Marek's disease virus), affecting primarily birds of the order Galliformes. This study reports a case of Marek's disease in Sebright chickens in Rio de Janeiro, Brazil.
Thomas Salles Dias, Catia Dejuste de Paula, Andrea Soffiatti Grael, Carlos Henrique Campelllo Costa, Aniesse Silva Aguiar, Dayse Lima da Costa Abreu   +5 more
wiley   +1 more source

Bovine Alphaherpesvirus 1, Bovine Alphaherpesvirus 5 and Bubaline Alphaherpesvirus 1 in Palatine Tonsils from Water Buffaloes in Northern Brazil and Possible Links with the Origin of Bovine Alphaherpesvirus Type 5

Viruses
Herpesviruses are significant pathogens of ruminants. In water buffaloes (Bubalus bubalis), however, herpesviruses have not been thoroughly studied. Although bubaline alphaherpesvirus 1 (BuAHV1) and bovine alphaherpesvirus 1 (BoAHV1) have already been recovered from water buffaloes, to date, no reports on the occurrence of bovine alphaherpesvirus 5 ...
Bruna Paredes-Galarza, Martha T. Oliveira, Francine B. Timm, Nicole V. Stone, Lina Violet-Lozano, Richard S. Salvato, Nícolas D. Müller, Bruno A. Prandi, Raíssa Gasparetto, Michelen Gonçalves, María A. S. Teixeira, Márcio A. O. Moura, Gabriela Riet-Correa, Valíria D. Cerqueira, Pedro S. Bezerra, Fabrício S. Campos, Ana C. Franco, Paulo M. Roehe   +17 more
openaire   +3 more sources

Alphaherpesviruses and the Cytoskeleton in Neuronal Infections

Viruses, 2011
Following infection of exposed peripheral tissues, neurotropic alphaherpesviruses invade nerve endings and deposit their DNA genomes into the nuclei of neurons resident in ganglia of the peripheral nervous system.
Gregory A. Smith, Kevin P. Bohannon, Sofia V. Zaichick   +2 more
doaj   +1 more source

Differentially-Charged Liposomes Interact with Alphaherpesviruses and Interfere with Virus Entry

Pathogens, 2020
Exposure of phosphatidylserine (PS) in the outer leaflet of the plasma membrane is induced by infection with several members of the Alphaherpesvirinae subfamily. There is evidence that PS is used by the equine herpesvirus type 1 (EHV-1) during entry, but
Oleksandr Kolyvushko, Juliane Latzke, Ismail Dahmani, Nikolaus Osterrieder, Salvatore Chiantia, Walid Azab   +5 more
doaj   +1 more source

Assembly and Egress of an Alphaherpesvirus Clockwork [PDF]

, 2017
All viruses produce infectious particles that possess some degree of stability in the extracellular environment yet disassemble upon cell contact and entry. For the alphaherpesviruses, which include many neuroinvasive viruses of mammals, these metastable virions consist of an icosahedral capsid surrounded by a protein matrix (referred to as the ...
openaire   +2 more sources

Alphaherpesvirus DNA replication in dissociated human trigeminal ganglia [PDF]

Journal of NeuroVirology, 2016
Analysis of the frequency and PCR-quantifiable abundance of herpes simplex virus type 1 (HSV-1) and varicella zoster virus (VZV) DNA in multiple biological replicates of cells from dissociated randomly distributed human trigeminal ganglia (TG) of four subjects revealed an increase in both parameters and in both viruses during 5 days of culture, with no
Randall J, Cohrs, Hussain, Badani, Nathan, Bos, Charles, Scianna, Ian, Hoskins, Nicholas L, Baird, Don, Gilden   +6 more
openaire   +2 more sources

Molecular characterization of equine herpes viruses type 1 and 4 among Arabian horse populations in Egypt during the period between 2021-2022

Open Veterinary Journal
Background: Equine herpesvirus type 1 (EHV-1) is a major cause of abortion and respiratory disease. Equine herpesvirus type 4 (EHV-4), on the other hand, is exclusively associated with respiratory disease in horse populations worldwide, particularly in ...
Ahmed A.H. Ali, Fatma Abdallah, Omayma A. Shemies, Gamilat A.H. Kotb, Maged R. Nafea   +4 more
doaj   +1 more source