Results 91 to 100 of about 15,327 (237)

In Vitro Inhibition of Alphaviruses by Lycorine

Virologica Sinica, 2021
Chikungunya virus (CHIKV) is a mosquito-borne alphavirus. As an emerging virus, CHIKV imposes a threat to public health. Currently, there are no vaccines or antivirals available for the prevention of CHIKV infection.
Na Li, Zhen Wang, Rui Wang, Zhe-Rui Zhang, Yanan Zhang, Chenglin Deng, Bo Zhang, Lu Shang, Hanqing Ye   +8 more
semanticscholar   +1 more source

Amphibian Strategies Against Attacks by Flies: Host‐Specificity and Threats

Ecology and Evolution, Volume 16, Issue 1, January 2026.
Species interactions between Diptera flies and amphibians play a significant role in tropical ecosystems, but their ecology and evolution remain understudied. This review explores the costs flies impose on amphibians, such as pathogen transmission and disruption of communication systems, and highlights the evolutionary strategies employed by both ...
Leonardo Leite Ferraz de Campos, Luiz Carlos Pinho, Selvino Neckel‐Oliveira, Ximena E. Bernal   +3 more
wiley   +1 more source

Evidence of Differences in Cellular Regulation of Wolbachia-Mediated Viral Inhibition between Alphaviruses and Flaviviruses

Viruses
The intracellular bacterium Wolbachia is increasingly being utilised in control programs to limit the spread of arboviruses by Aedes mosquitoes. Achieving a better understanding of how Wolbachia strains can reduce viral replication/spread could be ...
Stephanie M. Rainey, Daniella A. Lefteri, Christie Darby, Alain Kohl, Andres Merits, Steven P. Sinkins   +5 more
doaj   +1 more source

Clinical, Serological, and Molecular Profile of Dengue Patients With Warning Signs During the 2024 Outbreak in Belo Horizonte, Brazil

Journal of Medical Virology, Volume 98, Issue 1, January 2026.
ABSTRACT Dengue poses a significant arboviral threat in Brazil, with 2024 recording the largest outbreak to date. This prospective observational study was conducted during the 2024 outbreak with unvaccinated patients at Eduardo de Menezes Hospital, Belo Horizonte.
Samille Henriques Pereira, Ana Paula Moreira Franco‐Luiz, Camila Tita Nogueira, Guilherme Otávio Varino Cornélio, Adelina Machado de Carvalho Nogueira, Vírginia Antunes de Andrade, Silvia Hees de Carvalho, Karen Cecília de Lima Torres, Vanessa Peruhype‐Magalhães, Olindo Assis Martins‐Filho, Jordana Grazziela Alves Coelho‐dos‐Reis, Andréa Teixeira‐Carvalho, Flávio Guimarães da Fonseca, Pedro Augusto Alves   +13 more
wiley   +1 more source

Alphavirus-Based Vaccines

Viruses, 2014
Alphavirus vectors have demonstrated high levels of transient heterologous gene expression both in vitro and in vivo and, therefore, possess attractive features for vaccine development.
Kenneth Lundstrom
doaj   +1 more source

Application of a Human Blood Brain Barrier Organ-on-a-Chip Model to Evaluate Small Molecule Effectiveness against Venezuelan Equine Encephalitis Virus

Viruses, 2022
The blood brain barrier (BBB) is a multicellular microenvironment that plays an important role in regulating bidirectional transport to and from the central nervous system (CNS).
Niloufar A. Boghdeh, Kenneth H. Risner, Michael D. Barrera, Clayton M. Britt, David K. Schaffer, Farhang Alem, Jacquelyn A. Brown, John P. Wikswo, Aarthi Narayanan   +8 more
doaj   +1 more source

Semliki Forest viiruse replikaasivalgu nsP1 uurimine [PDF]

, 2013
Väitekirja elektrooniline versioon ei sisalda publikatsioone.Semliki Forest viirus kuulub alfaviiruste perekonda sugukonnas Togaviridae. Alfaviirused on olulised patogeenid ning põhjustavad erinevaid vaevusi nii loomadele kui ka inimestele.
Karo-Astover, Liis
core  

Why enveloped viruses need cores -- the contribution of a nucleocapsid core to viral budding

, 2017
During the alphavirus lifecycle, a nucleocapsid core buds through the cell membrane to acquire an outer envelope of lipid membrane and viral glycoproteins. However, the presence of a nucleocapsid core is not required for assembly of infectious particles.
Hagan, Michael F., Lazaro, Guillermo R., Mukhopadhyay, Suchetana   +2 more
core   +1 more source

Yaoundé-like virus in resident wild bird, Ghana [PDF]

, 2012
Tissue and swab samples from 551 wild birds collected in Ghana (October-November 2007) were assayed for alphaviruses, flaviviruses, and influenza A viruses using polymerase chain (PCR) techniques.
Ampofo, William, Asante, Ivy, Bonney, Kofi, Odoom, Shirley, Peterson, A. Townsend, Puplampu, Naiki, Sánchez-Seco, María Paz, Tenorio, Antonio, Vázquez, Ana, Williams, Richard   +9 more
core   +3 more sources

Semliki Forest Virus Chimeras with Functional Replicase Modules from Related Alphaviruses Survive by Adaptive Mutations in Functionally Important Hot Spots

Journal of Virology, 2021
Alphaviruses cause debilitating symptoms and have caused massive outbreaks. There are currently no approved antivirals or vaccines for treating these infections.
Mona Teppor, E. Žusinaite, Liis Karo-Astover, Ailar Omler, Kai Rausalu, V. Lulla, A. Lulla, A. Merits   +7 more
semanticscholar   +1 more source