Results 121 to 130 of about 15,705 (275)

An All‐in‐One Metabarcoding Approach to Mosquito and Arbovirus Xenosurveillance

Molecular Ecology Resources, Volume 25, Issue 8, November 2025.
ABSTRACT Next‐generation sequencing (NGS) has the potential to transform mosquito‐borne disease surveillance but remains under‐utilised. This study introduces a comprehensive multi‐loci metabarcoding‐based MX (molecular xenomonitoring) approach to mosquito and arbovirus surveillance, enabling parallel identification of mosquito vectors, circulating ...
Brian J. Johnson, Melissa C. Graham, Elina Panahi, Carla Julia S. P. Vieira, Nisa Suraj Nath, Paul Mason, Jamie Gleadhill, Darran Thomas, Michael B. Onn, Martin A. Shivas, Damien Shearman, Jonathan M. Darbro, Gregor J. Devine   +12 more
wiley   +1 more source

IFIT1 differentially interferes with translation and replication of alphavirus genomes and promotes induction of type I interferon [PDF]

, 2015
Alphaviruses are a group of widely distributed human and animal pathogens. It is well established that their replication is sensitive to type I IFN treatment, but the mechanism of IFN inhibitory function remains poorly understood.
Atasheva, Svetlana, Diamond, Michael S, Frolov, Ilya, Frolova, Elena I, Kim, Dal Young, Rasalouskaya, Aliaksandra, Reynaud, Josephine M, Weaver, Scott C, White, James P   +8 more
core   +4 more sources

Behaviour and Dispersal of Mobile Salmon Lice When Detached From the Host

Journal of Fish Diseases, Volume 48, Issue 11, November 2025.
ABSTRACT Sea lice can flourish when salmon are farmed in open sea‐cages, necessitating treatments to control outbreaks and reduce larval export. However, mobile ectoparasitic stages can be dislodged during crowding or other procedures, and potentially reinfest farmed or wild fish.
Luke T. Barrett, Mari F. Jensen, Sussie Dalvin, Frode Oppedal   +3 more
wiley   +1 more source

Broad Antiviral Activity of Ginkgolic Acid against Chikungunya, Mayaro, Una, and Zika Viruses

Viruses, 2020
The alphaviruses Chikungunya (CHIKV), Mayaro (MAYV), Una (UNAV), and the flavivirus Zika (ZIKV) are emerging or re-emerging arboviruses which are responsible for frequent epidemic outbreaks. Despite the large impact of these arboviruses on health systems,
Dalkiria Campos, Susana Navarro, Yessica Yadira Llamas-González, Madelaine Sugasti, José González-Santamaría   +4 more
doaj   +1 more source

Evolution-guided functional analyses reveal diverse antiviral specificities encoded by IFIT1 genes in mammals. [PDF]

, 2016
IFIT (interferon-induced with tetratricopeptide repeats) proteins are critical mediators of mammalian innate antiviral immunity. Mouse IFIT1 selectively inhibits viruses that lack 2'O-methylation of their mRNA 5' caps.
Daugherty, Matthew D, Geballe, Adam P, Malik, Harmit S, Schaller, Aaron M   +3 more
core   +1 more source

Negeviruses Reduce Replication of Alphaviruses during Coinfection

bioRxiv, 2020
Negeviruses are a group of insect-specific viruses (ISVs), viruses known to infect only insects. They have been discovered over a wide geographical and species range. ABSTRACT Negeviruses are a group of insect-specific viruses (ISVs) that have been found
Edward I. Patterson, Tiffany F Kautz, M. Contreras-Gutiérrez, H. Guzmán, R. Tesh, G. Hughes, N. Forrester   +6 more
semanticscholar   +1 more source

Comparing Genome Sequencing Methods to Reconstruct the Spread of Piscine Myocarditis Virus in Ireland

Journal of Fish Diseases, Volume 48, Issue 11, November 2025.
ABSTRACT Piscine myocarditis virus (PMCV), a double‐stranded RNA virus, is the causative agent of cardiomyopathy syndrome (CMS) in Atlantic salmon Salmo salar, which was first reported in Ireland in 2012. PMCV continues to be a disease threat to Atlantic salmon aquaculture in Ireland, and as such, it is of growing importance to understand how the virus
Andrew J. Tighe, Jens Carlsson, Neil M. Ruane   +2 more
wiley   +1 more source

Sensitivity of Alphaviruses to G3BP Deletion Correlates with Efficiency of Replicase Polyprotein Processing

Journal of Virology, 2020
Old World alphaviruses comprise several medically relevant viruses, including chikungunya virus and Ross River virus. Recurrent outbreaks and the lack of antivirals and vaccines demand ongoing research to fight the emergence of these infectious diseases.
Benjamin Götte, Age Utt, R. Fragkoudis, A. Merits, G. McInerney   +4 more
semanticscholar   +1 more source

Serum Biomarkers in Atlantic Salmon for Differential Diagnosis of Cardiomyopathy Syndrome and Pancreas Disease: Proteomic Identification of Serum Fibrinogen to Enhance Troponin Immunoassay as Optimal Diagnostic Approach

Journal of Fish Diseases, Volume 48, Issue 11, November 2025.
ABSTRACT Cardiac viral diseases are among the major causes of economic losses in Atlantic salmon (Salmo salar L.) aquaculture. These include cardiomyopathy syndrome (CMS) caused by piscine myocarditis virus (PMCV) and pancreas disease (PD) caused by Atlantic salmonid alphavirus (SAV).
Francesca Riva, Lauren Elaine Black, Kim D. Thompson, Philippe Sourd, Andrei Bordeianu, Christopher C. Chadwick, Hooman Moghadam, Jorge Del‐Pozo, Janina Costa, Richard Burchmore, Nicola Brady, Lewis Moore, Suzanne McGill, Mark McLaughlin, Peter David Eckersall   +14 more
wiley   +1 more source

Defined mutations in the 5' nontranslated sequence of Sindbis virus RNA [PDF]

, 1990
We have constructed 24 deletion mutants which contain deletions of from 1 to 15 nucleotides in the 5' nontranslated region of Sindbis virus RNA and tested the effect of these mutations on virus replication.
Niesters, Hubert G. M., Strauss, James H.   +1 more
core   +2 more sources