Results 61 to 70 of about 15,705 (275)

First Record of Mosquito-Borne Kyzylagach Virus in Central Europe

open access: yesViruses, 2020
RNA of Kyzylagach virus (KYZV), a Sindbis-like mosquito-borne alphavirus from Western equine encephalitis virus complex, was detected in four pools (out of 221 pools examined), encompassing 10,784 female Culex modestus mosquitoes collected at a fishpond ...
Silvie Šikutová   +8 more
doaj   +1 more source

The Pathogenesis of Alphaviruses [PDF]

open access: hybridISRN Virology, 2012
Alphaviruses are enveloped single-stranded positive sense RNA viruses of the family Togaviridae. The genus alphavirus contains nine viruses, which are of medical, theoretical, or economic importance, and which will be considered. Sindbis virus (SINV) and Semliki Forest (SFV), although of some medical importance, have largely been studied as models of ...
Gregory J. Atkins
openalex   +2 more sources

The low-density lipoprotein receptor promotes infection of multiple encephalitic alphaviruses

open access: yesNature Communications
Members of the low-density lipoprotein receptor (LDLR) family, including LDLRAD3, VLDLR, and ApoER2, were recently described as entry factors for different alphaviruses.
Hongming Ma   +8 more
semanticscholar   +1 more source

The interferon-induced exonuclease ISG20 exerts antiviral activity through upregulation of type I interferon response proteins [PDF]

open access: yes, 2018
The host immune responses to infection lead to the production of type I interferon (IFN), and the upregulation of interferon-stimulated genes (ISGs) reduces virus replication and virus dissemination within a host.
Diamond, Michael S   +6 more
core   +2 more sources

LDLR is used as a cell entry receptor by multiple alphaviruses

open access: yesNature Communications
Alphaviruses are arboviruses transmitted by mosquitoes and are pathogenic to humans and livestock, causing a substantial public health burden. So far, several receptors have been identified for alphavirus entry; however, they cannot explain the broad ...
Xiaofeng Zhai   +14 more
semanticscholar   +1 more source

MARCO+ lymphatic endothelial cells sequester arthritogenic alphaviruses to limit viremia and viral dissemination

open access: yesEMBO Journal, 2021
Viremia in the vertebrate host is a major determinant of arboviral reservoir competency, transmission efficiency, and disease severity. However, immune mechanisms that control arboviral viremia are poorly defined. Here, we identify critical roles for the
Kathryn S Carpentier   +12 more
semanticscholar   +1 more source

Top-Down and Bottom-Up Proteomics Methods to Study RNA Virus Biology

open access: yesViruses, 2021
RNA viruses cause a wide range of human diseases that are associated with high mortality and morbidity. In the past decades, the rise of genetic-based screening methods and high-throughput sequencing approaches allowed the uncovering of unique and ...
Yogy Simanjuntak   +4 more
doaj   +1 more source

Wild birds as carriers of antimicrobial-resistant and ESBL-producing Enterobacteriaceae [PDF]

open access: yes, 2016
open6noopenDotto, G.; Menandro, M.L.; Mondin, A.; Martini, M.; Tonellato, F.R.; Pasotto, D.Dotto, Giorgia; Menandro, MARIA LUISA; Mondin, Alessandra; Martini, Marco; Tonellato, F.
Dotto, Giorgia   +5 more
core   +1 more source

Non-replicating adenovirus based Mayaro virus vaccine elicits protective immune responses and cross protects against other alphaviruses

open access: yesPLoS Neglected Tropical Diseases, 2021
Mayaro virus (MAYV) is an alphavirus endemic to South and Central America associated with sporadic outbreaks in humans. MAYV infection causes severe joint and muscle pain that can persist for weeks to months.
J. Powers   +13 more
semanticscholar   +1 more source

Venezuelan Equine Encephalitis Complex Alphavirus in Bats, French Guiana

open access: yesEmerging Infectious Diseases, 2021
Although essential for control strategies, knowledge about transmission cycles is limited for Venezuelan equine encephalitis complex alphaviruses (VEEVs).
Carlo Fischer   +7 more
doaj   +1 more source

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