Results 81 to 90 of about 15,327 (237)

Encephalitic Alphaviruses Exploit Caveola-Mediated Transcytosis at the Blood-Brain Barrier for Central Nervous System Entry

open access: yesmBio, 2020
VEEV, WEEV, and eastern equine encephalitis virus (EEEV) are emerging infectious diseases in the Americas, and they have caused several major outbreaks in the human and horse population during the past few decades.
H. Salimi   +8 more
semanticscholar   +1 more source

MARCO+ lymphatic endothelial cells sequester arthritogenic alphaviruses to limit viremia and viral dissemination

open access: yesEMBO Journal, 2021
Viremia in the vertebrate host is a major determinant of arboviral reservoir competency, transmission efficiency, and disease severity. However, immune mechanisms that control arboviral viremia are poorly defined. Here, we identify critical roles for the
Kathryn S Carpentier   +12 more
semanticscholar   +1 more source

LDL receptor in alphavirus entry: structural analysis and implications for antiviral therapy

open access: yesNature Communications
Various low-density lipoprotein receptors (LPRs) have been identified as entry factors for alphaviruses, and structures of the corresponding virion-receptor complexes have been determined. Here, we analyze the similarities and differences in the receptor
Ningning Wang   +10 more
doaj   +1 more source

Ross River virus disease in two Dutch travellers returning from Australia, February to April 2015 [PDF]

open access: yes, 2015
We report two cases of Ross River virus (RRV) infection in Dutch travellers who visited Australia during February to April 2015. These cases coincided with the largest recorded outbreak of RRV disease in Australia since 1996. This report serves to create
Bloembergen, P.   +8 more
core   +5 more sources

Bee products as alternatives in the treatment of viral infections

open access: yesJournal of the Science of Food and Agriculture, Volume 106, Issue 1, Page 33-54, 15 January 2026.
Abstract Medicines used in the treatment of viral infections usually reduce symptoms. There is a need to develop drugs that inhibit the viruses and do not merely relieve the symptoms. Natural bee products possess many pharmacological properties and are widely used in folk medicine. There are many studies on the antibacterial effects of bee products but
Michał Otręba   +3 more
wiley   +1 more source

Plasmid DNA-based Alphavirus Vaccines

open access: yesVaccines, 2019
Alphaviruses have been engineered as vectors for high-level transgene expression. Originally, alphavirus-based vectors were applied as recombinant replication-deficient particles, subjected to expression studies in mammalian and non-mammalian cell lines,
Kenneth Lundstrom
doaj   +1 more source

Payload‐Driven Design of Polymeric Carriers for Nucleic Acid Delivery: Insights from Structure–Function Relationships

open access: yesAdvanced Science, Volume 13, Issue 4, 19 January 2026.
Polymeric carriers provide versatile platforms for nucleic acid delivery. This review introduces a novel perspective inspired by protein structural organization to explore structure–function relationships of polymeric carriers, highlighting requirements of different nucleic acid payloads.
Hanieh Moradian   +3 more
wiley   +1 more source

Expression of Sindbis virus structural proteins via recombinant vaccinia virus: synthesis, processing, and incorporation into mature Sindbis virions [PDF]

open access: yes, 1985
We have obtained a vaccinia virus recombinant which contains a complete cDNA copy of the 26S RNA of Sindbis virus within the thymidine kinase gene of the vaccinia virus genome.
Franke, Christine A.   +3 more
core  

New insights into control of arbovirus replication and spread by insect RNA interference pathways [PDF]

open access: yes, 2012
Arthropod-borne (arbo) viruses are transmitted by vectors, such as mosquitoes, to susceptible vertebrates. Recent research has shown that arbovirus replication and spread in mosquitoes is not passively tolerated but induces host responses to control ...
Andersson   +55 more
core   +3 more sources

Epidemic Alphaviruses: Ecology, Emergence and Outbreaks

open access: yesMicroorganisms, 2020
Over the past century, the emergence/reemergence of arthropod-borne zoonotic agents has been a growing public health concern. In particular, agents from the genus Alphavirus pose a significant risk to both animal and human health.
Sasha R. Azar   +4 more
semanticscholar   +1 more source

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