Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova+18 more
wiley +1 more source
The Factor H protein family: The switchers of the complement alternative pathway. [PDF]
Lucientes-Continente L+2 more
europepmc +1 more source
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma+9 more
wiley +1 more source
Bacterial outer membrane vesicles provide an alternative pathway for trafficking of Escherichia coli O157 type III secreted effectors to epithelial cells. [PDF]
Sirisaengtaksin N+4 more
europepmc +1 more source
Activation of the alternative complement pathway due to resistance of zymosan-bound.
Douglas T. Fearon, K. Frank Austen
openalex +1 more source
IL-21 initiates an alternative pathway to induce proinflammatory TH17 cells
T. Korn+7 more
semanticscholar +1 more source
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu+12 more
wiley +1 more source
An alternative pathway to plant cold tolerance in the absence of vacuolar invertase activity. [PDF]
Teper-Bamnolker P+16 more
europepmc +1 more source
Requirements of immunoglobulin and the classical and alternative complement pathways for phagocytosis and intracellular killing of multiple strains of Gram-negative aerobic bacilli [PDF]
P Leist-Welsh, A. B. Bjornson
openalex +1 more source
The acidic pathway of bile acid synthesis: Not just an alternative pathway
W. Pandak, Genta Kakiyama
semanticscholar +1 more source