Results 181 to 190 of about 1,609,187 (354)

ALTERNATIVE COMPLEMENT PATHWAY (AP) IN CHILDREN WITH NEPHROSIS (CN) [PDF]

, 1977
Michael E. Norman, Arlene Taylor, Ulf Nilsson, Mary Ann South   +3 more
openalex   +1 more source

Comprehensive profiling of lncRNAs and mRNAs enriched in small extracellular vesicles for early noninvasive detection of colorectal cancer: diagnostic panel assembly and extensive validation

Molecular Oncology, EarlyView.
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova, Marketa Pavlikova, Lucie Pifkova, Robin Jugas, Tana Machackova, Lenka Radova, Milana Sachlova, Renata Bartosova, Tetiana Samoilenko, Zuzana Feckova, Jana Orlickova, Erika Slamova, Elleni Ponechal Michu, Dagmar Al Tukmachi, Michaela Ruckova, Martina Vodinska, Jan Kotoucek, Tina Catela Ivkovic, Marie Boudna, Lucia Bohovicova, Teodor Stanek, Jana Halamkova, Martin Svoboda, Vladimir Prochazka, Tomas Grolich, Zdenek Kala, Ondrej Slaby   +26 more
wiley   +1 more source

Regulatable Complement Inhibition of the Alternative Pathway Mitigates Wet Age-Related Macular Degeneration Pathology in a Mouse Model. [PDF]

Transl Vis Sci Technol, 2023
Parsons NB, Annamalai B, Rohrer B.
europepmc   +1 more source

The critical role of DNA damage‐inducible transcript 4 (DDIT4) in stemness character of leukemia cells and leukemia initiation

Molecular Oncology, EarlyView.
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li, Zhijie Cao, Haiyan Xing, Zhenya Xue, Wenbing Liu, Jiayuan Chen, Yihan Mei, Runxia Gu, Hui Wei, Shaowei Qiu, Min Wang, Qing Rao, Jianxiang Wang   +12 more
wiley   +1 more source

Editorial: Telomere Flexibility and Versatility: A Role of Telomeres in Adaptive Potential

Frontiers in Genetics, 2021
Radmila Čapková Frydrychová, Radmila Čapková Frydrychová, James M. Mason, Vratislav Peska   +3 more
doaj   +1 more source

MASP3 Deficiency in Mice Reduces but Does Not Abrogate Alternative Pathway Complement Activity Due to Intrinsic Profactor D Activity. [PDF]

J Immunol, 2023
Gullipalli D, Miwa T, Golla M, Sato S, Angampalli S, Song WC.   +5 more
europepmc   +1 more source

Alternative Pathway of Complement Activation in Full Term and Premature Infants

, 1979
Robert C. Strunk, Lawrence J. Fenton, John A. Gaines   +2 more
openalex   +1 more source

Activation of the Alternative Complement Pathway by Blood Culture Isolates of Bacteroides fragilis [PDF]

, 1981
Keith A. Joiner, Alexandra Hawiger, Jeffrey A. Gelfand   +2 more
openalex   +1 more source

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

Molecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi, Mirjam Balbisi, Simon Sugár, Lóránd Váncza, Eszter Regős, Ilona Kovalszky, Ibolya Laczó, Tünde Harkó, Gábor Kecskeméti, Zoltán Szabó, Judit Moldvay, László Drahos, Lilla Turiák   +12 more
wiley   +1 more source

Structural studies offer a framework for understanding the role of properdin in the alternative pathway and beyond. [PDF]

Immunol Rev, 2023
Pedersen DV, Lorentzen J, Andersen GR.
europepmc   +1 more source