Results 131 to 140 of about 8,493 (176)

Antidotes to Experimental cc-Amanitin Poisoning

Nature New Biology, 1972
THE two most important toxic cyclopeptides isolated from the mushroom Amanita phalloides (death cap) are phalloidin and α-amanitin1, 2. The latter is considered to be responsible for the fatal cases of poisoning. Up to now, protection has been demonstrated either with a non-toxic chemical analogue (antamanide) isolated from the toadstool itself and ...
openaire   +2 more sources

α-Amanitin: Inactivation by bovine lactoperoxidase

Experientia, 1979
The principle amatoxin, alpha-amanitin, is found to be extremely sensitive toward lactoperoxidase catalyzed degradation, rather than iodination, of the indole nucleus. Extensive attenuation of inhibitor potency against eukaryotic DNA-dependent RNA polymerase II accompanies the treatment of alpha-amanitin with lactoperoxidase, iodide and hydrogen ...
P W, Morris, K M, Kelley, W G, Logas
openaire   +2 more sources

Unique amanitin resistance of RNA synthesis in isolated nuclei from Amanita species accumulating amanitins

Archives of Microbiology, 1979
In order to understand the basis upon which amanitin-accumulating species of Amanita are able to develop in the presence of these specific inhibitors of RNA synthesis, the in vitro RNA synthesizing activities of nuclei isolated from amanitin-accumulating species.
B C, Johnson, J F, Preston
openaire   +2 more sources

New Aspects of Amanitin and Phalloidin Poisoning

1996
The green death cap Amanita phalloides produces two families of toxic peptides, the amatoxins and the phallotoxins. Amatoxins are by far the more dangerous toxins and account for all fatalities occurring in human mushroom poisoning.
H, Faulstich, T, Wieland
openaire   +2 more sources

Rapid detection of α-amanitin and β-amanitin in rat plasma by ultra-performance liquid chromatography–tandem mass spectrometry and its application to the toxicokinetic study of Lepiota brunneoincarnata

Forensic Toxicology, 2021
Youjia Yu, Feng Chen, Yue Cao
exaly  

Amanitine

2018
C. Vidal, W.-R. Külpmann
openaire   +1 more source

Production of high purity beta amanitin

2012
Amaç: Beta amanitin nadiren bilimsel araştırmalarda kullanılmakta ve kullanımı gün geçtikçeartmaktadır. Piyasada bu ürün %90 saflıkta ticari olarak satılmaktadır. Bu araştırmada yükseksaflıkta beta amanitin üretme yöntemi tanımlanmıştır.Yöntem: Saflaştırma işlemi Amanita phalloides mantarlarından ekstraksiyonla yapılmıştır.Öncelikle bu mantarlar ...
YAYKAŞLI, Kürşat Oğuz, KARAHAN, Selim, BAYRAM, Recep, SARITAŞ, Ayhan, YAYKAŞLI, Emine, KAYA, Ertuğrul   +5 more
openaire   +3 more sources

α-amanitin induces autophagy through AMPK-mTOR-ULK1 signaling pathway in hepatocytes

Toxicology Letters, 2023
Genmeng Yang, Chi-Kwan Leung, Ruilin Zhang   +2 more
exaly  

amanitine, n.

2023
openaire   +1 more source

A Convergent Total Synthesis of the Death Cap Toxin α-Amanitin

Angewandte Chemie - International Edition, 2020
Roderich D. Süssmuth, Mary-Ann J Siegert   +1 more
exaly