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A Family of Sodium Solid‐State Electrolytes Based on the NaGaxAl1‐xCl4 Solid Solution
Advanced Materials Interfaces, EarlyView.ABSTRACT Sodium‐based metal chloride solid electrolytes are promising for sodium solid‐state batteries due to their excellent oxidation stability, which, as shown for Li halides, can coexist with high ionic conductivity. To explore cationic substitution effects, we synthesized NaGaxAl1‐xCl4 (0 ≤ x ≤ 1) via ball milling and investigated structural and ...
Hao Guo, Matteo Bianchini
wiley +1 more source
Interface‐Engineered Binary Framework Composites: Advancing Porous Materials for Precision Medicine
Advanced Materials Interfaces, EarlyView.Binary framework composites integrate two complementary porous architectures into a unified platform, enabling multifunctional design, enhanced structural tunability, and improved physicochemical performance. By combining high surface area, ordered porosity, interfacial synergy, and versatile functionalization, these hybrid materials offer new ...
Navid Rabiee +3 more
wiley +1 more source
Expert Opinion on Drug Delivery, 2016 Introduction: Amorphous solid dispersions are considered as one of the most powerful strategies to formulate poorly soluble drugs. They are made up of an active pharmaceutical ingredient (API) dispersed at the molecular level in an amorphous polymeric ...
Tu Van Duong, Guy Van Den Mooter
exaly +2 more sources
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Sustained-release amorphous solid dispersions
Drug Delivery and Translational Research, 2018The use of amorphous solid dispersions (ASD) to overcome poor drug solubility has gained interest in the pharmaceutical industry over the past decade. ASDs are challenging to formulate because they are thermodynamically unstable, and the dispersed drugs tend to recrystallize.
Julien, Maincent, Robert O, Williams
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Assessing the performance of amorphous solid dispersions
Journal of Pharmaceutical Sciences, 2012The characterization and performance of stable amorphous solid dispersion systems were evaluated in 40 research papers reporting active pharmaceutical ingredient (API) dissolution and bioavailability from various systems containing polymers. The results from these studies were broadly placed into three categories: amorphous dispersions that improved ...
Ann, Newman +2 more
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Dissolution testing of amorphous solid dispersions
International Journal of Pharmaceutics, 2013The main purpose of this study was to investigate the effect of different polymers, with varying physicochemical properties and molecular weight on the stability and dissolution of co-milled amorphous solid dispersions (ASDs) of piroxicam (PRX). The stability of amorphous PRX (aPRX) in ASDs was significantly improved by the polymers.
K, Kogermann +6 more
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Characterization of amorphous solid dispersions
Journal of Pharmaceutical Investigation, 2017The study of amorphous solid dispersions (ASDs) is currently one of the most exciting areas in pharmaceutics. Research has shown that ASDs offer unique advantages in improving the bioavailability of poorly water-soluble drugs over conventional delivery systems.
Xu Liu +3 more
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Amorphous solid dispersions of darunavir: Comparison between spray drying and electrospraying
European Journal of Pharmaceutics and Biopharmaceutics, 2018 The interest in using electrospraying as a manufacturing method for amorphous solid dispersions has grown remarkably. However, the impact of formulation and process parameters needs further clarification.
Robin Koekoekx +2 more
exaly +2 more sources
Multifractal and mechanical analysis of amorphous solid dispersions
International Journal of Pharmaceutics, 2017The formulation of lipophilic and hydrophobic compounds is a challenge for the pharmaceutical industry and it requires the development of complex formulations. Our first aim was to investigate hot-melt extrudate microstructures by means of multifractal analysis using scanning electron microscopy imaging. Since the microstructure can affect solid dosage
Adler C, Teleki A, Kuentz M
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Downstream processing of amorphous solid dispersions into orodispersible tablets
International Journal of Pharmaceutics, 2023The formulation development of amorphous solid dispersions (ASDs) towards a patient-friendly oral solid dosage form is proving to be still challenging. To increase patient's compliance orodispersible tablets (ODTs) can be seen as promising alternative.
Marcel, Kokott +3 more
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