AMPA Receptor-Mediated Ca2+ Transients in Mouse Olfactory Ensheathing Cells
Ca2+ signaling in glial cells is primarily triggered by metabotropic pathways and the subsequent Ca2+ release from internal Ca2+ stores. However, there is upcoming evidence that various ion channels might also initiate Ca2+ rises in glial cells by Ca2 ...
Antonia Beiersdorfer, Christian Lohr
doaj +1 more source
Evolutionarily conserved pattern of AMPA receptor subunit glycosylation in Mammalian frontal cortex. [PDF]
Protein glycosylation may contribute to the evolution of mammalian brain complexity by adapting excitatory neurotransmission in response to environmental and social cues.
Janusz Tucholski+3 more
doaj +1 more source
Interaction of GABA and Excitatory Amino Acids in the Basolateral Amygdala: Role in Cardiovascular Regulation [PDF]
Activation of the amygdala in rats produces cardiovascular changes that include increases in heart rate and arterial pressure as well as behavioral changes characteristic of emotional arousal.
Cook, Jennifer C.+3 more
core +2 more sources
Resensitizing AMPA receptors [PDF]
JGP study suggests how the regulatory protein γ8 reopens AMPA receptor channels in the continued presence of glutamate.
openaire +2 more sources
Recurrent Anti-AMPA Receptor Limbic Encephalitis: A Case Report and Literature Review
Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor encephalitis is a relatively rare anti-neuronal surface antigen autoimmune encephalitis (LE).
Yuanyuan Fang, Dengji Pan, Hao Huang
doaj +1 more source
Direct imaging of lateral movements of AMPA receptors inside synapses [PDF]
Trafficking of AMPA receptors in and out of synapses is crucial for synaptic plasticity. Previous studies have focused on the role of endo/exocytosis processes or that of lateral diffusion of extra-synaptic receptors. We have now directly imaged AMPAR movements inside and outside synapses of live neurons using single-molecule fluorescence microscopy ...
arxiv +1 more source
Cyclin Y inhibits plasticity-induced AMPA receptor exocytosis and LTP [PDF]
Cyclin Y (CCNY) is a member of the cyclin protein family, known to regulate cell division in proliferating cells. Interestingly, CCNY is expressed in neurons that do not undergo cell division.
Cho, Eunsil+9 more
core +1 more source
Stargazin Dephosphorylation Mediates Homeostatic Synaptic Downscaling of Excitatory Synapses
Synaptic scaling is a form of homeostatic plasticity that is critical for maintaining neuronal activity within a dynamic range, and which alters synaptic strength through changes in postsynaptic AMPA-type glutamate receptors.
Susana R. Louros+3 more
doaj +1 more source
Reduced Effect of Anticonvulsants on AMPA Receptor Palmitoylation-Deficient Mice
AMPA receptors are responsible for fast excitatory synaptic transmission in the mammalian brain. Post-translational protein S-palmitoylation of AMPA receptor subunits GluA1-4 reversibly regulates synaptic AMPA receptor expression, resulting in long ...
Madoka Iizumi+4 more
doaj +1 more source
Postsynaptic Synaptotagmins Mediate AMPA Receptor Exocytosis During LTP
Strengthening of synaptic connections by NMDA (N-methyl-d-aspartate) receptor-dependent long-term potentiation (LTP) shapes neural circuits and mediates learning and memory.
Dick Wu+8 more
semanticscholar +1 more source