Distinct serum endocannabinoid profiles in treatment-naïve Han Chinese children with ADHD: a case–control pilot study [PDF]
Frontiers in NeurologyObjectiveAlthough peripheral endocannabinoid system (ECS) signatures have been implicated in ADHD among European and American populations, evidence from Asian pediatric cohorts remains scarce.
Wenjuan Liao +7 more
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Exploiting nanotechnologies and TRPV1 channels to investigate the putative anandamide membrane transporter. [PDF]
PLoS ONE, 2010 Considerable efforts have been made to characterize the pathways regulating the extracellular levels of the endocannabinoid anandamide. However, none of such pathways has been so argued as the existence of a carrier-mediated transport of anandamide ...
Alessia Ligresti +10 more
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High-fat diet-induced insulin resistance does not increase plasma anandamide levels or potentiate anandamide insulinotropic effect in isolated canine islets. [PDF]
PLoS ONE, 2015 BACKGROUND:Obesity has been associated with elevated plasma anandamide levels. In addition, anandamide has been shown to stimulate insulin secretion in vitro, suggesting that anandamide might be linked to hyperinsulinemia.
Orison O Woolcott +18 more
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The insertion and transport of anandamide in synthetic lipid membranes are both cholesterol-dependent. [PDF]
PLoS ONE, 2009 Anandamide is a lipid neurotransmitter which belongs to a class of molecules termed the endocannabinoids involved in multiple physiological functions. Anandamide is readily taken up into cells, but there is considerable controversy as to the nature of ...
Eric Di Pasquale +3 more
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Cell Reports, 2020 Summary: Endocannabinoids protect against seizures, but their mechanism of action is still unclear, as they can have effects independent of known cannabinoid receptors. Using Drosophila melanogaster, which lacks canonical cannabinoid receptors, we report
Jack A. Jacobs, Amita Sehgal
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Reduced endothelium-dependent relaxation to anandamide in mesenteric arteries from young obese Zucker rats. [PDF]
PLoS ONE, 2013 Impaired vascular function, manifested by an altered ability of the endothelium to release endothelium-derived relaxing factors and endothelium-derived contracting factors, is consistently reported in obesity.
Nubia S Lobato +8 more
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Anandamide induces sperm release from oviductal epithelia through nitric oxide pathway in bovines. [PDF]
PLoS ONE, 2012 Mammalian spermatozoa are not able to fertilize an egg immediately upon ejaculation. They acquire this ability during their transit through the female genital tract in a process known as capacitation.
Claudia Osycka-Salut +6 more
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Anandamide-ceramide interactions in a membrane environment: Molecular dynamic simulations data
Data in Brief, 2017 Anandamide is a lipid neurotransmitter that interacts with various plasma membrane lipids. The data here consists of molecular dynamics simulations of anandamide, C18-ceramide and cholesterol performed in vacuo and within a hydrated palmitoyl-oleoyl ...
Coralie Di Scala +6 more
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Biomolecules, 2018 Anandamide is a lipid neurotransmitter derived from arachidonic acid, a polyunsaturated fatty acid. The chemical differences between anandamide and arachidonic acid result in a slightly enhanced solubility in water and absence of an ionisable group for ...
Coralie Di Scala +4 more
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Anandamide capacitates bull spermatozoa through CB1 and TRPV1 activation. [PDF]
PLoS ONE, 2011 Anandamide (AEA), a major endocannabinoid, binds to cannabinoid and vanilloid receptors (CB1, CB2 and TRPV1) and affects many reproductive functions.
María Gracia Gervasi +7 more
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