Results 51 to 60 of about 11,917 (183)
Effect of Anandamide on Erythrocyte Survival [PDF]
Cellular Physiology and Biochemistry, 2007 The endocannabinoid anandamide (Arachidonylethanolamide, AEA) is known to induce apoptosis in a wide variety of nucleated cells. The present study explored whether anandamide induces suicidal death of erythrocytes or eryptosis, which is characterized by cell shrinkage and cell membrane scrambling with phosphatidylserine exposure at the erythrocyte ...
Peter J, Bentzen, Florian, Lang
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Liver International, Volume 46, Issue 4, April 2026.ABSTRACT Metabolic dysfunction‐associated fatty liver disease (MAFLD), recently redefined from non‐alcoholic fatty liver disease (NAFLD), highlights the central role of metabolic dysfunction in its pathophysiology. The L‐α‐lysophosphatidylinositol/G protein‐coupled receptor 55 (LPI/GPR55) axis, an element of the endocannabinoidome, has emerged as a key
Jerome Lian +3 more
wiley +1 more source
Fiyz̤, 2022 Background: Aerobic exercise, ozone therapy and cell therapy have each been independently proposed as treatments for osteoarthritis. Therefore, the present study aimed to investigate the effect of aerobic exercise with ozone and cell therapy on serum ...
Maryam Rezaei +3 more
doaj
Two Vanilloid Ligand Bindings Per Channel Are Required to Transduce Capsaicin-Activating Stimuli
Frontiers in Molecular Neuroscience, 2020 The tetrameric capsaicin receptor transient receptor potential vanilloid 1 (TRPV1) in mammals has evolved the capability to integrate pain signal arising from harmful temperature and chemical irritants. The four repetitions of TRPV1 subunits result in an
Ting-Yi Liu +4 more
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Oxygenation of Anandamide by Lipoxygenases
, 2016 The endocannabinoids anandamide and 2-arachidonoylglycerol are not only metabolized by serine hydrolases, such as fatty acid amide hydrolase, monoacylglycerol lipase, and α,β-hydrolases 6 and 12, but they also serve as substrates for cyclooxygenases, cytochrome P450s, and lipoxygenases.
Zadelhoff, G. van, Stelt, M. van der
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International Journal of Quantum Chemistry, Volume 126, Issue 5, March 5, 2026.Cannabidiol (CBD) exhibits increased reactivity, stronger CB1 receptor binding, and enhanced cytotoxicity against A431 squamous carcinoma cells compared to 5‐fluorouracil (5‐FU). Integrated DFT, molecular docking, and experimental analyses demonstrate CBD's improved stability and binding affinity, highlighting its potential as an alternative ...
Andrea Jess Josiah +5 more
wiley +1 more source
Cancer Reports, Volume 9, Issue 3, March 2026.ABSTRACT Background Fetal calf serum (FCS) is a key supplement in cell culture, providing nutrients, and growth factors that support cancer cell proliferation. Studies suggest that compound cytotoxicity profiles in vitro vary depending on FCS concentration in culture medium. The study aimed to examine how extracellular conditions influence the in vitro
Sanele Priscillia Mathibela +2 more
wiley +1 more source
Endocannabinoids and related N-acylethanolamines: biological activities and metabolism
Inflammation and Regeneration, 2018 The plant Cannabis sativa contains cannabinoids represented by Δ9-tetrahydrocannabinol, which exert psychoactivity and immunomodulation through cannabinoid CB1 and CB2 receptors, respectively, in animal tissues. Arachidonoylethanolamide (also referred to
Kazuhito Tsuboi +3 more
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Food Frontiers, Volume 7, Issue 2, March 2026.MFGM modulated gut microbiota accompanied by the increased serum RVD1 and AEA levels, which subsequently regulated the miRNA profile. This modulation alleviated neuroinflammation via suppressing the NLRP3 inflammasome signaling and microglial activation, thereby attenuating AD‐related cognitive impairment both in vivo and in vitro.
Han Gong +4 more
wiley +1 more source
Release of anandamide from blood cells [PDF]
Clinical Chemistry and Laboratory Medicine (CCLM), 2006 Abstract
Vogeser, Michael +5 more
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